Nexchio IT 40mg/150mg Tablet

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Rs.194for 1 strip(s) (10 tablets each)
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Composition FOR Nexchio IT

Esomeprazole(40mg),Itopride(150mg)

food interaction for Nexchio IT

alcohol interaction for Nexchio IT

pregnancy interaction for Nexchio IT

lactation interaction for Nexchio IT

food
alcohol
pregnancy
lactation
Nexchio IT 40mg/150mg Tablet is to be taken empty stomach.
Take Nexchio IT 40mg/150mg Tablet 30 minutes before food.
None
CAUTION
Caution is advised when consuming alcohol with Nexchio IT 40mg/150mg Tablet. Please consult your doctor.
CAUTION
Nexchio IT 40mg/150mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Nexchio IT 40mg/150mg Tablet during breastfeeding is not available. Please consult your doctor.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Nexchio IT

Esomeprazole(40mg)

Uses

Esomeprazole is used in the treatment of gastroesophageal reflux disease (acid reflux) and peptic ulcer disease.

How it works

Esomeprazole is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in relief of acid related indigestion and heartburn.

Common side effects

Headache, Dizziness, Dryness in mouth, Nausea, Abdominal pain, Flatulence, Diarrhea, Increased liver enzymes, Sleepiness, Vomiting, Paresthesia (tingling or pricking sensation), Insomnia (difficulty in sleeping), Vertigo, Itching, Rash, Red spots or bumps, General discomfort, Peripheral edema, Dermatitis, Agitation, Confusion, Depression, Increased sweating, Interstitial nephritis, Bronchospasm, Joint pain, Muscle pain, Hepatitis (viral infection of liver), Stomatitis (Inflammation of the mouth), Gastrointestinal candidiasis, Blurred vision, Taste change
Itopride(150mg)

Uses

Itopride is used in the treatment of heartburn and nausea.

How it works

Itopride is a prokinetic. It works on the region in the brain that controls vomiting. It also acts on the upper digestive tract to increase the movement of the stomach and intestines, allowing food to move more easily through the stomach.

Common side effects

Diarrhea, Headache, Abdominal pain, Chest pain, Constipation, Decreased white blood cell count, Dizziness, Fatigue, Increased saliva production, Sleep disorder, Increased prolactin level in blood, Irritability, Back pain, Increased blood urea, Increased creatinine level in blood, Rash, Erythema (skin redness), Itching

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Expert advice FOR Nexchio IT

  • It is a well-tolerated medicine and provides relief for a long time.
  • Some healthy tips to prevent acidity from happening:
    • Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
    • Avoid alcohol and smoking.
    • Avoid eating late at night or before bedtime.
  • Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
  • Long-term use of Esomeprazole can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
  • Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.

Frequently asked questions FOR Nexchio IT

Esomeprazole

Q. What is the best time to take Esomeprazole?
Usually, Esomeprazole is taken once a day, first thing in the morning. If you take Esomeprazole twice a day, take 1 dose in the morning and 1 dose in the evening. The tablets should be swallowed whole (remember not be chewed or crushed) and taken at least 1 hour before a meal with some water.
Q. Can I take antacids along with Esomeprazole?
Yes, you can take antacids along with Esomeprazole. Take it 2 hours before or after you take Esomeprazole.
Q. Can I take Esomeprazole with domperidone?
Yes, Esomeprazole can be safely taken with domperidone as no harmful effects have been reported clinically. A fixed-dose combination of these two medicines is also available. Domperidone works by increasing the gut motility and Esomeprazole decreases the acid production in the stomach. So, this combination is very effective in the treatment of reflux esophagitis associated with acidity, heartburn, intestinal and stomach ulcers.
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Q. Can I take Esomeprazole for a long term?
Esomeprazole is usually prescribed for short term use only. However, if need arises, such as for treating peptic ulcer disease and Zollinger Ellison syndrome (ZES), Esomeprazole may be prescribed for a long term duration as well. Long term use may carry an increased risk for side effects and must be discussed with the doctor. Please use Esomeprazole as advised by your doctor and under their supervision.
Q. Can I stop taking Esomeprazole if I feel better?
If you have been taking Esomeprazole for a long time, stopping it abruptly may lead to increased acid production, thereby worsening your symptoms. Therefore, you must discuss any dose changes or if you wish to come off Esomeprazole.
Q. Can Esomeprazole cause weight gain?
Weight gain is reported in less than 1% of the patients taking Esomeprazole but the exact cause is unknown. One possible explanation is higher food intake once the reflux symptoms are relieved. Lifestyle modifications such as proper diet and exercise can help to prevent weight gain.
Q. Is Esomeprazole safe to use?
Yes, Esomeprazole is relatively safe to use. Most of the people who take Esomeprazole do not get a side effect. It is advised to be taken as directed by the doctor for maximum benefit.
Q. What are the long term side effects of Esomeprazole?
If Esomeprazole is used for more than 3 months, certain long term side effects may be seen. The most important of these is low magnesium levels in your blood which may make you feel tired, confused, dizzy, shaky or dizzy. You may also have muscle twitches or irregular heartbeat. If the use is further prolonged for more than a year, you may have an increased risk of bone fractures, stomach infections and vitamin B12 deficiency. Vitamin B12 deficiency can make you anemic, as a result of which you may feel more tired, weak, or pale. Additionally you may have palpitations, shortness of breath, lightheadedness, indigestion, loss of appetite, flatulence (gas) or nerve problems such as numbness, tingling and problem in walking.
Q. Can I take Esomeprazole with ranitidine?
Yes, Esomeprazole can be taken with ranitidine. According to research reports, there are no significant interactions seen between Esomeprazole and ranitidine. However, you must take them together only if prescribed by the doctor.
Q. Can I take alcohol with Esomeprazole?
No, alcohol intake is not advised with Esomeprazole. Alcohol itself does not affect the working of Esomeprazole, but it can increase the acid production. This may further cause worsening of your symptoms

Itopride

Q. Is Itopride safe in pregnancy?
Due to lack of safety data, Itopride should not be used during pregnancy or in women suspected with pregnancy until and unless the benefits outweigh the risks. Discuss with your doctor who will analyze your condition and decide whether you can take Itopride during pregnancy or not.
Q. How long can I take Itopride?
Itopride is recommended to be taken thrice daily before meals. The duration of therapy will depend on the response of the patient towards the therapy. The exact dose and duration will be decided by your doctor depending on individual need and response.
Q. Is Itopride bad for kidneys?
Itopride and its metabolites are mainly excreted via the kidneys. Therefore, people with any kidney problems should remain careful while taking Itopride. Regular tests for kidney function are required and if side effects related to kidneys (creatinine increased) occur, the medicine is generally discontinued or the dose is reduced.
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Q. Who should not take Itopride?
Itopride should not be given to patients in whom there is an increase in gastrointestinal movements. It is harmful in patients having mechanical obstruction or perforation of the gastrointestinal tract or gastrointestinal bleeding.
Q. Should I take Itopride before or after meals?
Food does not interfere with the working of Itopride. This medicine is generally recommended to be taken before meals.

Content on this page was last updated on 29 November, 2023, by Dr. Varun Gupta (MD Pharmacology)