food interaction for Cafonate Injection

alcohol interaction for Cafonate Injection

pregnancy interaction for Cafonate Injection

lactation interaction for Cafonate Injection

food
alcohol
pregnancy
lactation
No interaction found/established
It is not known whether it is safe to consume alcohol with Cafonate 50mg Injection. Please consult your doctor.
CONSULT YOUR DOCTOR
Cafonate 50mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Cafonate 50mg Injection during breastfeeding is not available. Please consult your doctor.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Cafonate 50mg Injection

Calcium Leucovorin(50mg)

Cafonate injection uses

{med_name} is used to prevent harmful effects of methotrexate. It is also used to treat overdose of methotrexate.

How cafonate injection works

Cafonate 50mg Injection is a form of vitamin B. It works by protecting healthy cells from the toxic effects of methotrexate (anticancer medicine) while allowing it to enter and kill the cancer cells.

Common side effects of cafonate injection

Injection site reactions (pain, swelling, redness)

SUBSTITUTES FOR Cafonate Injection

24 Substitutes
24 Substitutes
Sorted By
RelevancePrice
  • Leucovorin Injection
    (5 ml Injection in vial)
    Dabur India Ltd
    Rs. 48.40/ml of Injection
    generic_icon
    Rs. 250
    save 9% more per ml of Injection
  • Biovorin Injection
    (5 ml Injection in vial)
    Biochem Pharmaceutical Industries
    Rs. 63.20/ml of Injection
    generic_icon
    Rs. 326
    pay 18% more per ml of Injection
  • Leucorin 50mg Injection
    (5 ml Injection in vial)
    Samarth Life Sciences Pvt Ltd
    Rs. 69.40/ml of Injection
    generic_icon
    Rs. 358
    pay 30% more per ml of Injection
  • Cevoric C 50mg Injection
    (1 Injection in vial)
    Health Biotech Limited
    Rs. 242/Injection
    Injection
    Rs. 250
    pay 353% more per Injection
  • Leucowel Injection
    (5 ml Injection in vial)
    Getwell Pharma (I) Pvt Ltd
    Rs. 39.80/ml of Injection
    generic_icon
    Rs. 280
    save 25% more per ml of Injection

Expert advice FOR Cafonate Injection

  • You have been prescribed Calcium Leucovorin to reduce the side effects of the medicine methotrexate.
  • Take it 24 hours after taking methotrexate. If taken at the same time, it may counteract the effect of methotrexate.
  • Inform your doctor if you are also taking certain medications such as phenytoin for your seizures as Calcium Leucovorin may counteract the antiepileptic effects.

Frequently asked questions FOR Cafonate 50mg Injection

Calcium Leucovorin

Q. What is Cafonate 50mg Injection used for?
Cafonate 50mg Injection is used to prevent harmful effects of methotrexate (cancer chemotherapy medication) when methotrexate is used to treat certain types of cancer. Cafonate 50mg Injection is also used to treat people who have accidentally received an overdose of methotrexate or similar medications. It is also used for the treatment of megaloblastic anemia due to folic acid deficiency and when oral therapy is not feasible.
Q. What is megaloblastic anemia?
Anemia is a blood disorder in which the number of red blood cells (RBCs) that carry oxygen is lower than usual. As a result, your tissues and organs don’t get enough oxygen. Megaloblastic anemia is a form of anemia characterized by very large red blood cells and a decrease in the number of those cells. Usually, megaloblastic anemia is due to vitamin B12 or folic acid deficiency. How long does it take for Cafonate 50mg Injection to work?
Q. How long does it take for Cafonate 50mg Injection to work?
Cafonate 50mg Injection starts acting on the body within 5 minutes of administration. However, this might vary with respect to dosage, the patient receiving the drug, and response to treatment.
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Q. What are some of the laboratory tests conducted before or during the treatment with Cafonate 50mg Injection?
Your doctor will prescribe blood tests to check your levels of serum methotrexate concentration (in case of methotrexate chemotherapy or overdose) to determine the optimal dose and duration of treatment with Cafonate 50mg Injection. You will also be prescribed a complete blood count to monitor the number of red blood cells (in case of megaloblastic anemia). Along with this, your calcium levels will also be monitored in order to prevent hypercalcemia (excess calcium) since Cafonate 50mg Injection contains calcium.
Q. What measures should be taken to ensure the prompt excretion of methotrexate during treatment with Cafonate 50mg Injection?
Maintenance of urine output above 2,500 mL/24hr in adults by increasing oral or intravenous fluids 12 hours before and for 36 hours after the end of methotrexate infusion. To monitor alkalinization of urine (this enhances drug excretion) so that the urinary pH is greater than 7.0 before methotrexate infusion. Foods, drinks, and drugs that may increase urinary acidity should be avoided during the therapy. Finally, blood methotrexate concentration should be measured at least 24, 48, and 72 hours after the initiation of the methotrexate infusion.

Content on this page was last updated on 12 January, 2024, by Dr. Varun Gupta (MD Pharmacology)