Biovorin Injection

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Rs.316for 1 vial(s) (5 ml Injection each)
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Composition FOR Biovorin 50mg Injection

Calcium Leucovorin(50mg)

food interaction for Biovorin Injection

alcohol interaction for Biovorin Injection

pregnancy interaction for Biovorin Injection

lactation interaction for Biovorin Injection

food
alcohol
pregnancy
lactation
No interaction found/established
It is not known whether it is safe to consume alcohol with Biovorin Injection. Please consult your doctor.
CONSULT YOUR DOCTOR
Biovorin Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Biovorin Injection during breastfeeding is not available. Please consult your doctor.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Biovorin 50mg Injection

Calcium Leucovorin(50mg)

Biovorin injection uses

{med_name} is used to prevent harmful effects of methotrexate. It is also used to treat overdose of methotrexate.

How biovorin injection works

Biovorin Injection is a form of vitamin B. It works by protecting healthy cells from the toxic effects of methotrexate (anticancer medicine) while allowing it to enter and kill the cancer cells.

Common side effects of biovorin injection

Injection site reactions (pain, swelling, redness)

SUBSTITUTES FOR Biovorin Injection

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24 Substitutes
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Expert advice FOR Biovorin Injection

  • You have been prescribed Calcium Leucovorin to reduce the side effects of the medicine methotrexate.
  • Take it 24 hours after taking methotrexate. If taken at the same time, it may counteract the effect of methotrexate.
  • Inform your doctor if you are also taking certain medications such as phenytoin for your seizures as Calcium Leucovorin may counteract the antiepileptic effects.

Frequently asked questions FOR Biovorin 50mg Injection

Calcium Leucovorin

Q. What is Biovorin Injection used for?
Biovorin Injection is used to prevent harmful effects of methotrexate (cancer chemotherapy medication) when methotrexate is used to treat certain types of cancer. Biovorin Injection is also used to treat people who have accidentally received an overdose of methotrexate or similar medications. It is also used for the treatment of megaloblastic anemia due to folic acid deficiency and when oral therapy is not feasible.
Q. What is megaloblastic anemia?
Anemia is a blood disorder in which the number of red blood cells (RBCs) that carry oxygen is lower than usual. As a result, your tissues and organs don’t get enough oxygen. Megaloblastic anemia is a form of anemia characterized by very large red blood cells and a decrease in the number of those cells. Usually, megaloblastic anemia is due to vitamin B12 or folic acid deficiency. How long does it take for Biovorin Injection to work?
Q. How long does it take for Biovorin Injection to work?
Biovorin Injection starts acting on the body within 5 minutes of administration. However, this might vary with respect to dosage, the patient receiving the drug, and response to treatment.
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Q. What are some of the laboratory tests conducted before or during the treatment with Biovorin Injection?
Your doctor will prescribe blood tests to check your levels of serum methotrexate concentration (in case of methotrexate chemotherapy or overdose) to determine the optimal dose and duration of treatment with Biovorin Injection. You will also be prescribed a complete blood count to monitor the number of red blood cells (in case of megaloblastic anemia). Along with this, your calcium levels will also be monitored in order to prevent hypercalcemia (excess calcium) since Biovorin Injection contains calcium.
Q. What measures should be taken to ensure the prompt excretion of methotrexate during treatment with Biovorin Injection?
Maintenance of urine output above 2,500 mL/24hr in adults by increasing oral or intravenous fluids 12 hours before and for 36 hours after the end of methotrexate infusion. To monitor alkalinization of urine (this enhances drug excretion) so that the urinary pH is greater than 7.0 before methotrexate infusion. Foods, drinks, and drugs that may increase urinary acidity should be avoided during the therapy. Finally, blood methotrexate concentration should be measured at least 24, 48, and 72 hours after the initiation of the methotrexate infusion.

Content on this page was last updated on 28 October, 2024, by Dr. Varun Gupta (MD Pharmacology)