Parona Plus 12.5mg/0.5mg Tablet CR

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Composition FOR Parona Plus

Paroxetine(12.5mg),Clonazepam(0.5mg)

food interaction for Parona Plus

alcohol interaction for Parona Plus

pregnancy interaction for Parona Plus

lactation interaction for Parona Plus

food
alcohol
pregnancy
lactation
Parona Plus 12.5mg/0.5mg Tablet CR may be taken with or without food, but it is better to take it at a fixed time.
None
CAUTION
It is unsafe to consume alcohol with Parona Plus 12.5mg/0.5mg Tablet CR.
UNSAFE
Parona Plus 12.5mg/0.5mg Tablet CR is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
UNSAFE
Parona Plus 12.5mg/0.5mg Tablet CR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Parona Plus

Paroxetine(12.5mg)

Uses

Paroxetine is used in the treatment of depression, Panic disorder and anxiety disorder.

How it works

Paroxetine is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms of depression and also relieves symptoms of panic and obsessive disorders.

Common side effects

Dryness in mouth, Dizziness, Tremors, Insomnia (difficulty in sleeping), Delayed ejaculation, Decreased libido, Weight gain, Abdominal pain, Abnormal dreams, Headache, Weakness, Diaphoresis, Gastrointestinal intolerance, Drowsiness, High blood pressure, Tachycardia, Joint pain, Itching, Ringing in ear, Impotence, Genital tract disease, Difficulty in urination, Agitation, Hypersensitivity, Seizure, Involuntary muscle movement, Increased liver enzymes, Dilatation of pupil, Cough, Adrenergic syndrome, Diabetes, Blood system abnormalities, Lymphatic system abnormalities, Visual disturbance
Clonazepam(0.5mg)

Uses

Clonazepam is used in the treatment of anxiety disorder and epilepsy/seizures.

How it works

Clonazepam is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Common side effects

Constipation, Blurred vision, Headache, Agitation, Skin rash, Urinary retention, Muscle weakness, Sleep disturbance, Abnormal behavior, Sleepiness, Cognitive impairment, Abnormality of voluntary movements, Depression, Nervousness, Upper respiratory tract infection, Allergic reaction, Influenza, Pain during periods, Difficulty in speaking, Emotional lability, Decreased libido, Change in body weight, Edema (swelling), Hypotension (low blood pressure), Migraine, Paresthesia (tingling or pricking sensation), Abdominal discomfort, Upset stomach, Infection, Acne, Discomfort when urinating, Eye irritation, Visual disturbance, Palpitations, Hair loss, Decreased appetite, Anemia (low number of red blood cells), Decreased white blood cell count (lymphocytes), Low blood platelets, Hepatomegaly (enlarged liver), Increased liver enzymes, Dehydration, Fever, Insomnia (difficulty in sleeping), Psychosis, Excitation, Irritability, Aggression, Hostility, Anxiety, Nightmares, Vivid dreams, Hypotonia (decreased muscle tone), Abnormal eye movements, Nystagmus (involuntary eye movement), Vertigo, Memory impairment, Dizziness, Fatigue, Drowsiness

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Expert advice FOR Parona Plus

  • It can take 2-3 weeks for Paroxetine to start working.
  • Do not stop treatment suddenly as this may cause upset stomach, flu-like withdrawal symptoms and sleep disturbance.
  • If your doctor asks you to stop Paroxetine, you should reduce the dose slowly over 4 weeks.
  • Avoid consuming alcohol when taking Paroxetine, as it may cause excessive drowsiness and calmness.
  • The addiction/dependence potential of Paroxetine is very less.

Frequently asked questions FOR Parona Plus

Paroxetine

Q. After how many days of taking Paroxetine will I start feeling better?
You may start to see an improvement in your symptoms after 1-2 weeks of starting the treatment. In case you do not see any improvement, do not stop the medicine and consult your doctor. It may take around 4-6 weeks to see the full benefits of the medicine.
Q. I feel that my symptoms have worsened after having started taking Paroxetine. Can I stop it on my own or do I need to consult the doctor?
No, do not stop taking Paroxetine abruptly, without consulting your doctor. This is a common problem with Paroxetine that initially you may feel that your symptoms have worsened but the benefits start appearing after 1-2 weeks. If the worsening does not improve even after 1-2 weeks, you must consult your doctor.
Q. Can Paroxetine affect my sex life?
Yes, Paroxetine use may affect your sex life. It can cause decreased sexual desire and inability to reach orgasm in both men and women. Additionally, men may even experience abnormal erection and ejaculation.
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Q. What is the effect of Paroxetine on children?
Paroxetine should not be used in children under 18 years of age. The reason being, patients under 18 have an increased risk of experiencing side effects such as suicidal thoughts, aggression, oppositional behavior and anger when they take Paroxetine. If your doctor has prescribed Paroxetine for your child and you are worried about these side effects, discuss it with your doctor.
Q. I have been taking tamoxifen for breast cancer. Can I take Paroxetine with it?
No, you should not take Paroxetine if you are receiving tamoxifen. Tamoxifen often causes hot flashes (episodes of feeling extremely hot), which can be treated with Paroxetine. But Paroxetine may reduce the effectiveness of tamoxifen and can lead to recurrence of breast cancer.
Q. Do I need to be careful while taking Paroxetine if I am a diabetic?
Yes, you need to be careful while taking this medicine if you are a diabetic. Paroxetine may alter your blood sugar levels and your dose of insulin or antidiabetic medicines may need adjustment. Talk to your doctor regarding this and keep a regular check on your blood sugar levels.

Clonazepam

Q. Is Clonazepam a sleeping pill?
Clonazepam belongs to a class of medicines called benzodiazepines and is used to treat anxiety, stop seizures (fits) or relax tense muscles. This can also help relieve difficulty sleeping (insomnia), and is usually prescribed for a short period of time, if used to treat sleeping problems. You should take it in the dose and duration advised by the doctor.
Q. Does Clonazepam cause sleepiness? If yes, then should I stop driving while taking Clonazepam?
Yes, Clonazepam causes drowsiness very commonly. It also causes forgetfulness and affects muscular function which may adversely affect your ability to drive. Sometimes, drowsiness persists even on the following day. So, in case Clonazepam makes you sleepy and affects your alertness, you should avoid driving.
Q. For how long should I take Clonazepam?
The duration of treatment with Clonazepam is mainly as short as possible. Your doctor will evaluate you after 4 weeks of treatment in order to assess the need for continuation of treatment, especially if you do not have any symptoms. Before taking you off this medicine, your doctor may gradually decrease your dose to prevent any withdrawal side effects. Follow your doctor’s instructions carefully to get the most benefit.
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Q. Is it safe to take Clonazepam and alcohol together?
No, it is not at all recommended to take alcohol with Clonazepam since it can cause breathing problems, sleepiness and heart problems. Taking Clonazepam with alcohol may make you sleepy and your breathing may become so shallow that you may not wake up. This may even lead to death.
Q. Is Clonazepam addictive?
People taking Clonazepam in high doses or for a long term may become addicted to it. Also, people with a history of alcoholism and drug abuse are more likely to become addicted to Clonazepam. Therefore, Clonazepam should be taken for the shortest possible time and in the lowest effective dose.
Q. Can I stop taking Clonazepam if I start feeling better?
No, do not stop taking Clonazepam suddenly as you may experience withdrawal effects like depression, nervousness, difficulty in sleeping, irritability, sweating, upset stomach or diarrhea. Stopping it suddenly may even bring back the symptoms and make them harder to treat. You may also experience mood changes, anxiety, restlessness and changes in sleep patterns. These effects may occur even after taking low doses for a short period of time.
Q. Are there any foods we need to avoid while taking Clonazepam?
Yes, you should avoid taking foods containing caffeine such as tea, coffee, chocolates etc., while taking Clonazepam. This is because caffeine stimulates your brain and Clonazepam calms the brain. So, taking too much caffeine can affect the calming ability of this medicine and worsen your condition. Also, you should avoid taking alcohol while on treatment with Clonazepam. Alcohol can cause excessive sleepiness and make you more drowsy and inattentive. Talk to your doctor if you have any other doubts regarding your diet while taking Clonazepam.

Content on this page was last updated on 10 November, 2024, by Dr. Varun Gupta (MD Pharmacology)