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MDD XR Plus 100 Tablet

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Composition FOR MDD Plus

Desvenlafaxine(100mg),Clonazepam(0.5mg)

food interaction for MDD Plus

alcohol interaction for MDD Plus

pregnancy interaction for MDD Plus

lactation interaction for MDD Plus

food
alcohol
pregnancy
lactation
MDD XR Plus 100 Tablet may be taken with or without food, but it is better to take it at a fixed time.
None
CAUTION
It is unsafe to consume alcohol with MDD XR Plus 100 Tablet.
UNSAFE
MDD XR Plus 100 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
MDD XR Plus 100 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR MDD Plus

Desvenlafaxine(100mg)

Uses

Desvenlafaxine is used in the treatment of depression.

How it works

Desvenlafaxine works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance.

Common side effects

Anxiety, Constipation, Decreased appetite, Dizziness, Insomnia (difficulty in sleeping), Nausea, Agitation, Blurred vision, Decreased libido, Diarrhea, Dilatation of pupil, Dryness in mouth, Fatigue, Headache, Sleepiness, Tremors, Vertigo, Weakness, Sweating, Vasodilation, Dyslipidemia, Anorgasmia (decreased orgasm), Abnormal dreams, Nervousness, Tachycardia, Weight gain, Musculoskeletal (bone, muscle or joint) pain, Fainting, Hypotension (low blood pressure), Urinary retention, SIADH (water retention due to excessive ADH), Torsade de pointes, Blood system abnormalities, Lymphatic system abnormalities, Convulsion, Dystonia (involuntary muscle contractions)
Clonazepam(0.5mg)

Uses

Clonazepam is used in the treatment of anxiety disorder and epilepsy/seizures.

How it works

Clonazepam is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Common side effects

Constipation, Blurred vision, Headache, Agitation, Skin rash, Urinary retention, Muscle weakness, Sleep disturbance, Abnormal behavior, Sleepiness, Cognitive impairment, Abnormality of voluntary movements, Depression, Nervousness, Upper respiratory tract infection, Allergic reaction, Influenza, Pain during periods, Difficulty in speaking, Emotional lability, Decreased libido, Change in body weight, Edema (swelling), Hypotension (low blood pressure), Migraine, Paresthesia (tingling or pricking sensation), Abdominal discomfort, Upset stomach, Infection, Acne, Discomfort when urinating, Eye irritation, Visual disturbance, Palpitations, Hair loss, Decreased appetite, Anemia (low number of red blood cells), Decreased white blood cell count (lymphocytes), Low blood platelets, Hepatomegaly (enlarged liver), Increased liver enzymes, Dehydration, Fever, Insomnia (difficulty in sleeping), Psychosis, Excitation, Irritability, Aggression, Hostility, Anxiety, Nightmares, Vivid dreams, Hypotonia (decreased muscle tone), Abnormal eye movements, Nystagmus (involuntary eye movement), Vertigo, Memory impairment, Dizziness, Fatigue, Drowsiness

SUBSTITUTES FOR MDD Plus

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Expert advice FOR MDD Plus

  • Desvenlafaxine helps in treating depression and anxiety.
  • It may also  be used to treat nerve pain from diabetes and some other forms of chronic pain.
  • It may take 2 to 4 weeks for Desvenlafaxine to start working. Keep taking it as prescribed.
  • It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Desvenlafaxine as it may cause excessive drowsiness and increase the risk of liver damage.
  • It may cause an increase in blood pressure, especially during the first month of treatment. Monitor your blood pressure regularly.
  • It may cause a sensation of restlessness, especially when you first start taking it. Inform your doctor if this happens to you.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Do not stop taking the medication suddenly without talking to your doctor.

Frequently asked questions FOR MDD Plus

Desvenlafaxine

Q. How long does it take for Desvenlafaxine to work?
The symptoms of depression like change in appetite and sleep patterns may show improvement within 1-2 weeks of starting Desvenlafaxine. However, it may take about 5-6 weeks to see the full benefits of Desvenlafaxine.
Q. Is Desvenlafaxine good for anxiety?
It has been shown to be effective in relieving symptoms of anxiety, though it is not approved for anxiety. It is used in anxiety disorders only when advised by the doctor.
Q. What time of the day is best to take Desvenlafaxine?
Desvenlafaxine can be taken either in the morning or in the evening. For best results, take this medicine at the same time each day. This will also help you remember to take it.
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Q. Can Desvenlafaxine be cut?
Desvenlafaxine should be swallowed whole with water. It should not be cut, chewed, crushed or dissolved. Take it exactly as directed by your doctor.
Q. How can Desvenlafaxine help treat depression?
Desvenlafaxine belongs to a class of medicines known as serotonin and norepinephrine reuptake inhibitors (SNRIs). Serotonin and norepinephrine are chemical messengers in the brain which help maintain mental balance. Desvenlafaxine works by increasing the levels of these two hormones in the brain.
Q. Will I gain weight while taking Desvenlafaxine?
Weight gain may occur with Desvenlafaxine, though not in everyone. In case you notice weight gain after taking Desvenlafaxine, consult your doctor or a nutritionist. Take a low calorie food, including more vegetables and fruits in your diet and exercise regularly.
Q. Will Desvenlafaxine affect my sex drive?
Taking Desvenlafaxine may cause a decrease in sexual desire and ability. It may also cause a delay in orgasm and ejaculation and sometimes ejaculation failure. Discuss with your doctor if you experience any of these symptoms while taking Desvenlafaxine.

Clonazepam

Q. Is Clonazepam a sleeping pill?
Clonazepam belongs to a class of medicines called benzodiazepines and is used to treat anxiety, stop seizures (fits) or relax tense muscles. This can also help relieve difficulty sleeping (insomnia), and is usually prescribed for a short period of time, if used to treat sleeping problems. You should take it in the dose and duration advised by the doctor.
Q. Does Clonazepam cause sleepiness? If yes, then should I stop driving while taking Clonazepam?
Yes, Clonazepam causes drowsiness very commonly. It also causes forgetfulness and affects muscular function which may adversely affect your ability to drive. Sometimes, drowsiness persists even on the following day. So, in case Clonazepam makes you sleepy and affects your alertness, you should avoid driving.
Q. For how long should I take Clonazepam?
The duration of treatment with Clonazepam is mainly as short as possible. Your doctor will evaluate you after 4 weeks of treatment in order to assess the need for continuation of treatment, especially if you do not have any symptoms. Before taking you off this medicine, your doctor may gradually decrease your dose to prevent any withdrawal side effects. Follow your doctor’s instructions carefully to get the most benefit.
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Q. Is it safe to take Clonazepam and alcohol together?
No, it is not at all recommended to take alcohol with Clonazepam since it can cause breathing problems, sleepiness and heart problems. Taking Clonazepam with alcohol may make you sleepy and your breathing may become so shallow that you may not wake up. This may even lead to death.
Q. Is Clonazepam addictive?
People taking Clonazepam in high doses or for a long term may become addicted to it. Also, people with a history of alcoholism and drug abuse are more likely to become addicted to Clonazepam. Therefore, Clonazepam should be taken for the shortest possible time and in the lowest effective dose.
Q. Can I stop taking Clonazepam if I start feeling better?
No, do not stop taking Clonazepam suddenly as you may experience withdrawal effects like depression, nervousness, difficulty in sleeping, irritability, sweating, upset stomach or diarrhea. Stopping it suddenly may even bring back the symptoms and make them harder to treat. You may also experience mood changes, anxiety, restlessness and changes in sleep patterns. These effects may occur even after taking low doses for a short period of time.
Q. Are there any foods we need to avoid while taking Clonazepam?
Yes, you should avoid taking foods containing caffeine such as tea, coffee, chocolates etc., while taking Clonazepam. This is because caffeine stimulates your brain and Clonazepam calms the brain. So, taking too much caffeine can affect the calming ability of this medicine and worsen your condition. Also, you should avoid taking alcohol while on treatment with Clonazepam. Alcohol can cause excessive sleepiness and make you more drowsy and inattentive. Talk to your doctor if you have any other doubts regarding your diet while taking Clonazepam.

Content on this page was last updated on 11 November, 2024, by Dr. Varun Gupta (MD Pharmacology)