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Difen Plus 50mg/325mg Tablet

Orison Pharmaceuticals
Tablet
Rs.18.30for 1 strip(s) (10 tablets each)
1
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Composition FOR Difen Plus

Diclofenac(50mg),Pantoprazole(325mg)

food interaction for Difen Plus

alcohol interaction for Difen Plus

pregnancy interaction for Difen Plus

lactation interaction for Difen Plus

food
alcohol
pregnancy
lactation
Difen Plus 50mg/325mg Tablet is to be taken empty stomach.
None
CAUTION
It is unsafe to consume alcohol with Difen Plus 50mg/325mg Tablet.
UNSAFE
Difen Plus 50mg/325mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
Difen Plus 50mg/325mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
SAFE IF PRESCRIBED

SALT INFORMATION FOR Difen Plus

Diclofenac(50mg)

Uses

Diclofenac is used for pain relief. It relieves pain in conditions like headache, mild migraine, muscle pain, dental pain, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, or painful menses.

How it works

Diclofenac is a non-steroidal anti-inflammatory drugs (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).

Common side effects

Nausea, Headache, Dizziness, Vomiting, Flatulence, Constipation, Diarrhea, Abdominal pain, Dyspepsia, Gastrointestinal bleeding, Gastrointestinal ulcer, Rash, Application site irritation, Injection site pain, Chest pain, Hypersensitivity, Angioneurotic edema, Platelet disorders, Convulsion, Visual disturbance, Ringing in ear, Colitis, Stevens-Johnson syndrome, Myocardial infarction
Pantoprazole(325mg)

Uses

Pantoprazole is used in the treatment of heartburn, gastroesophageal reflux disease (acid reflux) and peptic ulcer disease.

How it works

Pantoprazole is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which in turn relieves acid-related indigestion and heartburn.

Common side effects

Diarrhea, Flatulence, Headache, Nausea, Vomiting, Dizziness, Abdominal pain, Blurred vision, Constipation, Joint pain, Injection site reaction, Edema (swelling), Dryness in mouth, Hepatitis (viral infection of liver), Decreased white blood cell count, Low blood platelets, Rash, Red spots or bumps, Fundic gland polyps, Jaundice, Systemic lupus erythematosus, Clostridium difficile associated diarrhea, Change in body weight, Increased triglyceride level in blood, Rhabdomyolysis

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Expert advice FOR Difen Plus

  • You have been prescribed Diclofenac to relieve pain and inflammation.
  • Take it with food or milk to prevent upset stomach.
  • Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
  • It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration.
  • Avoid consuming alcohol while taking Diclofenac as it can cause excessive drowsiness and increase your risk of stomach problems.
  • Inform your doctor if you have a history of heart disease or stroke.
  • Your doctor may regularly monitor your kidney function, liver function and levels of blood components, if you are taking this medicine for long-term treatment.

Frequently asked questions FOR Difen Plus

Diclofenac

Q. Is Diclofenac a good painkiller?
Diclofenac is effective in relieving pain and inflammation. It is used for various sorts of pain such as sprains, strains and other injuries. It is also helpful in various types of arthritis, gout, pain and inflammation following surgery.
Q. Is Diclofenac a narcotic?
No, Diclofenac is not a narcotic. It belongs to non-steroidal anti-inflammatory drugs (NSAIDs) group of medicines.
Q. Does Diclofenac get you high?
No, Diclofenac does not get you high. It does not have an abuse potential (drug-seeking behavior) and does not cause physical or psychological dependence. However, if you do not feel well, consult your doctor.
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Q. Can Diclofenac damage your kidneys?
Long-term use and high doses of Diclofenac may cause renal problems such as protein or blood in urine and painful urination. Patients who are at maximum risk of developing kidney problems include people who are dehydrated, have heart failure, impaired kidney function, hypertension, elderly, who are on medicines which cause excess urination (diuretics), or medicines which have significant impact on kidney function. Hence, for such patients kidney function monitoring is recommended.
Q. Does Diclofenac make you drowsy?
Diclofenac can cause drowsiness and also dizziness, fatigue (tiredness) and visual disturbances. However, it is not very common and may not affect everyone. If you experience these symptoms avoid driving or operating heavy machinery.
Q. What is the most important information I need to know about Diclofenac?
It is important to know that Diclofenac may increase your chance of having a heart attack or stroke. The risk is more if you take higher doses and have been using the medicine for a longer time. Also, taking Diclofenac may cause ulcers, bleeding, or holes in your stomach and intestine. These problems may happen without warning symptoms at any time during treatment and may even cause death. Therefore, if you encounter any such problems, consult your doctor immediately.
Q. Can Diclofenac be taken during pregnancy?
You should not take Diclofenac during the last 3 months of pregnancy as it may cause harmful effects on your baby. Use of Diclofenac can also lead to reduced labor (premature delivery). Hence, it is advised to avoid using Diclofenac during the first 6 months of pregnancy also. In some cases, Diclofenac may be prescribed in pregnant women only if the benefits outweigh the risks involved with its use in pregnant women. If not sure, consult your doctor regarding its use.

Pantoprazole

Q. What is Pantoprazole used for?
Pantoprazole is used for the treatment of peptic ulcer disease, reflux esophagitis or gastroesophageal reflux disease (GERD). Pantoprazole prevents acidity associated with use of painkillers. It is also used to treat a disease associated with excessive acid production in the stomach known as Zollinger Ellison syndrome (ZES). It works by reducing the amount of acid made by your stomach and thus relieves your symptoms.
Q. How long does it take for Pantoprazole to work?
You should start to feel better within 2 to 3 days. It may take up to 4 weeks for Pantoprazole to work properly so you may still have some symptoms during this time.
Q. Is Pantoprazole safe?
Yes, Pantoprazole is relatively safe. Most of the people who take Pantoprazole do not get a side effect. It is advised to be taken as directed by the doctor for maximum benefits.
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Q. Can I take Pantoprazole for a long term?
Pantoprazole is usually prescribed for short term use only. However, if need arises, such as for treating peptic ulcer disease and Zollinger Ellison syndrome (ZES), Pantoprazole may be prescribed for a long term duration as well. Long term use may carry an increased risk for side effects and must be discussed with the doctor. Please use Pantoprazole as advised by your doctor and under their supervision.
Q. What are the long term side effects of Pantoprazole?
If Pantoprazole is used for more than 3 months, certain long term side effects may be seen. The most important of these is low magnesium levels in your blood which may make you feel tired, confused, dizzy, shaky or dizzy. You may also have muscle twitches or irregular heartbeat. If the use is further prolonged for more than a year, you may have an increased risk of bone fractures, stomach infections and vitamin B12 deficiency. Vitamin B12 deficiency can make you anemic, as a result of which you may feel more tired, weak, or pale. Additionally you may have palpitations, shortness of breath, lightheadedness, indigestion, loss of appetite, flatulence (gas) or nerve problems such as numbness, tingling and problem in walking.
Q. What is the best time to take Pantoprazole?
Usually, Pantoprazole is taken once a day, first thing in the morning. If you take Pantoprazole twice a day, take 1 dose in the morning and 1 dose in the evening. The tablets should be swallowed whole (remember not be chewed or crushed) and taken at least 1 hour before a meal with some water.
Q. Is a single dose of Pantoprazole sufficient?
No, a single dose may not be sufficient. However, with only a few doses of Pantoprazole you may get relief with the symptoms. Pantoprazole is usually needed only for a short term or upto 2 weeks for heartburn, indigestion, acid reflux. However, if need arises, such as for treating peptic ulcer disease and Zollinger Ellison syndrome (ZES), Pantoprazole may be prescribed for a long term duration as well. Please consult your doctor if you do not feel better even after taking Pantoprazole regularly for 2 weeks as prescribed.
Q. Can I stop taking Pantoprazole if I feel better?
If you have been taking Pantoprazole for a long time, stopping it abruptly may lead to increased acid production, thereby worsening your symptoms. Therefore, you must discuss with your doctor about any dose changes or if you wish to come off Pantoprazole.
Q. Does Pantoprazole cause weight gain?
Although rare but long-term treatment with Pantoprazole may cause weight gain. The reason could be the relief from reflux symptoms which could make you eat more. Consult your doctor for any weight-related concern.
Q. Can I take alcohol with Pantoprazole?
No, alcohol intake is not advised with Pantoprazole. Alcohol itself does not affect the working of Pantoprazole, but it can increase the acid production. This may further cause worsening of your symptoms.
Q. Can I take antacids along with Pantoprazole?
Yes, you can take antacids along with Pantoprazole. Take it 2 hours before or after you take Pantoprazole.
Q. What dietary changes should I make to get relief from acidity?
Pantoprazole is best taken 1 hour before a meal. You should avoid spicy and fatty foods while taking this medicine. You must refrain from caffeinated drinks such as tea, coffee and cola. Alcohol intake should also be avoided as it may worsen your symptoms.
Q. Are painkillers safe to take along with Pantoprazole?
Yes, it is safe to take painkillers along with Pantoprazole. Pantoprazole prevents acidity and stomach ulcers associated with the intake of painkillers. Pantoprazole is taken 1 hour before a meal. On the other hand, painkillers are usually taken with, or after a meal to avoid stomach upset.

Content on this page was last updated on 29 November, 2023, by Dr. Varun Gupta (MD Pharmacology)