Depsol Plus 2 mg/25 mg Tablet

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Composition FOR Depsol Plus

Diazepam(2mg),Imipramine(25mg)

food interaction for Depsol Plus

alcohol interaction for Depsol Plus

pregnancy interaction for Depsol Plus

lactation interaction for Depsol Plus

food
alcohol
pregnancy
lactation
Depsol Plus 2 mg/25 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
None
CAUTION
It is unsafe to consume alcohol with Depsol Plus 2 mg/25 mg Tablet.
UNSAFE
Depsol Plus 2 mg/25 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
Depsol Plus 2 mg/25 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Depsol Plus

Diazepam(2mg)

Uses

Diazepam is used in the treatment of short term anxiety, alcohol withdrawal, muscle spasm and epilepsy.

How it works

Diazepam is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Common side effects

Drowsiness, Fatigue, Confusion, Depression, Dizziness, Dryness in mouth, Headache, Impaired concentration, Slurred speech, Urinary retention, Abnormality of voluntary movements, Sensory motor disorders, Tremors, Withdrawal symptoms, Anterograde amnesia, Balance disorder (loss of balance), Respiratory depression, Allergic skin condition, Gastrointestinal disorder, Salivary hypersecretion, Myasthenia (weakness and rapid fatigue of muscle), Blood dyscrasias, Insomnia (difficulty in sleeping), Loss of consciousness, Psychiatric disturbances, Paradoxical reactions, Emotional lability, Change in alertness, Heart failure, Hypotension (low blood pressure), Increased appetite, Abnormal liver function tests, Vision disorder, Apnea (absence of breathing), Anaphylactic reaction
Imipramine(25mg)

Uses

Imipramine is used in the treatment of depression and bed-wetting. It is used in patients intolerant of or unresponsive to other treatment options for depression.

How it works

Imipramine is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Common side effects

Orthostatic hypotension (sudden lowering of blood pressure on standing), Gastrointestinal disturbance, Nervousness, Sleep disorder, Tiredness, Cardiac conduction abnormalities, High blood pressure, Tachycardia, Hallucination, Black tongue, Parotid gland swelling, Unusual production of breast milk in women and men, Bone marrow suppression

SUBSTITUTES FOR Depsol Plus

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Expert advice FOR Depsol Plus

  • Diazepam helps treat short term anxiety.
  • Safety of this medicine is not established for long-term use. Do not use it for more than 4 weeks. 
  • The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Avoid consuming alcohol as it may increase dizziness and drowsiness.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.

Frequently asked questions FOR Depsol Plus

Diazepam

Q. Is Diazepam an antidepressant? What is it used for?
Diazepam is not an antidepressant and belongs to a group of medicines called benzodiazepine. It is used to treat severe anxiety (an emotional state where you may sweat, tremble, feel anxious and have a fast heartbeat) or agitation. It is also used to treat trembling, muscle spasm due to tetanus or poisoning, seizures or fits, confusional states or anxiety associated with alcohol withdrawal. It also helps in relaxing patients before minor operations or procedures.
Q. How long does it take for Diazepam to start working?
It depends on what you are taking Diazepam for. If you are taking it to treat anxiety, you should start feeling better within a few hours, but it may take a week or two before the full benefits become evident. Similarly, if you are taking it to relieve muscle spasm you may notice a difference after 15 minutes. Your muscles will start relaxing when you keep taking Diazepam regularly for a few days.
Q. Does Diazepam cause sleepiness? If yes, then should I stop driving while taking Diazepam?
Yes, Diazepam causes drowsiness very commonly. It also causes forgetfulness and affects muscular function which may adversely affect your ability to drive. Sometimes, drowsiness persists even on the following day. So, in case Diazepam makes you sleepy and affects your alertness, you should avoid driving.
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Q. Is it safe to take Diazepam and alcohol together?
No, it is not at all recommended to take alcohol with Diazepam since it can cause breathing problems, sleepiness and heart problems. Taking Diazepam with alcohol may make you sleepy and your breathing may become so shallow that you may not wake up. This may even lead to death.
Q. Is Diazepam addictive?
People taking Diazepam in high doses or for a long term may become addicted to it. Also, people with a history of alcoholism and drug abuse are more likely to become addicted to Diazepam. Therefore, Diazepam should be taken for the shortest possible time and in the lowest effective dose.
Q. Can I stop taking Diazepam if I start feeling better?
No, do not stop taking Diazepam suddenly as you may experience withdrawal effects like depression, nervousness, difficulty in sleeping, irritability, sweating, upset stomach or diarrhea. Stopping it suddenly may even bring back the symptoms and make them harder to treat. You may also experience mood changes, anxiety, restlessness and changes in sleep patterns. These effects may occur even after taking low doses for a short period of time.
Q. For how long should I take Diazepam?
The duration of treatment with Diazepam is mainly as short as possible. Your doctor will evaluate you after 4 weeks of treatment in order to assess the need of continuation of treatment, especially if you do not have any symptoms. In general, the treatment does not last any longer than 8-12 weeks which includes the gradual reduction of dose process.
Q. Does Diazepam have any effect on contraception?
Diazepam does not affect the functioning of any type of contraception including the birth control pills and emergency contraception. Birth control pills can keep Diazepam in your body for a long time and increase its effect. You can also experience bleeding in between your periods if you take Diazepam and birth control pills together. But your contraceptive method will still work.
Q. Is it safe to take clozapine and Diazepam together?
No, it is not recommended to take clozapine and Diazepam together because the effects of both medicines may get added together. This can result in severe drop in blood pressure, breathing problems (respiratory depression) and can even stop your heart which can lead to death.
Q. Is Diazepam safe to be used in elderly patients?
The dose in elderly is generally half of the dose recommended to young people. This is because Diazepam causes muscle relaxation which can make the patient fall down, which may further lead to fractures.

Imipramine

Q. What is Imipramine used for?
Imipramine is mainly used to treat depression. It is also used to treat bed wetting in children older than 6 years of age. It works by restoring the chemical imbalance in the brain, thereby enhancing mood and behavior.
Q. What are the side effects of Imipramine?
Imipramine may cause side effects like increased heart rate, blurred vision, dryness in mouth, difficulty in urination, constipation and orthostatic hypotension (sudden decrease in blood pressure on standing). Consult your doctor if these side effects do not go away or worry you.
Q. Can I just stop taking Imipramine?
No, you must not stop taking Imipramine suddenly even if you are feeling good as it may worsen your condition. Continue taking Imipramine for the duration prescribed by your doctor to get maximum benefit. If any of the side effects are bothering you, consult your doctor. In case you have completed your course of treatment, your doctor will reduce your dose gradually before taking you off this medicine completely.
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Q. Can a pregnant woman take Imipramine?
No, pregnant women should avoid taking Imipramine, unless recommended by the doctor. Studies have shown significant risks to the developing baby and it is given only if the benefits are clearly more than the risks involved. Taking this medicine during the last trimester of the pregnancy may cause symptoms such as breathing problems, weakness, irritability, changes in blood pressure, tremors, and spasms in the newborn. Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant or breastfeeding.
Q. Does Imipramine make you sleepy?
Yes, Imipramine may make you feel sleepy. Therefore, it is advised that you should not drive, use any heavy machinery or do any work that requires concentration while taking Imipramine. Also, refrain from taking alcohol if you are being treated with Imipramine as it will increase your drowsiness.

Content on this page was last updated on 11 November, 2024, by Dr. Varun Gupta (MD Pharmacology)