food interaction for Cibutol Plus

alcohol interaction for Cibutol Plus

pregnancy interaction for Cibutol Plus

lactation interaction for Cibutol Plus

food
alcohol
pregnancy
lactation
Cibutol Plus 300mg/800mg Tablet is to be taken empty stomach.
Avoid Cibutol Plus 300mg/800mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
CAUTION
Consuming alcohol while taking Cibutol Plus 300mg/800mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
UNSAFE
Cibutol Plus 300mg/800mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Cibutol Plus 300mg/800mg Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
SAFE IF PRESCRIBED

SALT INFORMATION FOR Cibutol Plus

Isoniazid(300mg)

Uses

Isoniazid is used in the treatment of tuberculosis. It is also used to treat inactive (latent) TB .

How it works

Isoniazid is an antibiotic. It works by killing the bacteria that causes tuberculosis.

Common side effects

Peripheral neuropathy (tingling and numbness of feet and hand), Hepatitis (viral infection of liver), Hemolytic anemia, Aplastic anemia, Agranulocytosis (deficiency of granulocytes in the blood), Skin rash, Lethargy, Psychosis, Joint pain, Anemia (low number of red blood cells), Optic neuritis, Deafness, Ringing in ear, Vertigo, Fever, Hypoglycemia (low blood glucose level), Breast enlargement in male, Toxic epidermal necrolysis, Increased white blood cell count (eosinophils), Increased liver enzymes, Pellagra, Drug-induced lupus syndrome, Constipation, Nausea, Pancreatic inflammation
Ethambutol(800mg)

Uses

Ethambutol is used in the treatment of tuberculosis.

How it works

Ethambutol is an antibiotic. It works by slowing the growth of bacteria that causes tuberculosis.

Common side effects

Vomiting, Nausea, Rash, Increased uric acid level in blood, Optic neuritis, Hepatitis (viral infection of liver), Low blood platelets, Decreased white blood cell count (lymphocytes), Decreased white blood cell count (neutrophils), Hypersensitivity, Gout precipitation, Peripheral neuropathy (tingling and numbness of feet and hand), Pneumonitis

SUBSTITUTES FOR Cibutol Plus

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Expert advice FOR Cibutol Plus

  • Your doctor has prescribed Isoniazid to cure your infection and improve symptoms.
  • It is best taken on an empty stomach.
  • You must also take a vitamin B6 supplement while on Isoniazid.
  • Tell your doctor immediately if you experience vision changes, loss of appetite, tiredness, stomach pain, nausea or vomiting, yellow skin or eyes or dark-colored urine.

Frequently asked questions FOR Cibutol Plus

Isoniazid

Q. Is Isoniazid an antibiotic?
Isoniazid is an antibiotic used in the prevention and treatment of tuberculosis or TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body)
Q. Is Isoniazid chemotherapy/chemotherapy drug?
Isoniazid is a primary antibiotic used for treatment of tuberculosis. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer
Q. Is Isoniazid bacteriostatic or bactericidal?
Isoniazid is a bacteriostatic antibiotic. It stops or suppresses growth of tuberculosis causing bacteria by interfering with the formation of protective outer covering (cell wall) which is essential for their growth
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Q. Is Isoniazid safe?
Yes. Isoniazid is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Q. Is Isoniazid a MAOI?
Isoniazid has very weak inhibitory activity on enzymes monoamine oxidases (MAO); however it is not used as a monoamine oxidase inhibitor (MAOI)
Q. Is Isoniazid a sulfa drug?
No. The chemical structure and mechanism of action of Isoniazid is different from sulfa drugs
Q. Is Isoniazid an inducer or inhibitor?
Isoniazid is an inhibitor (decreases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body
Q. Can I take isoniazid with ibuprofen/Benadryl/Nyquil/Aleve/Mucinex/amoxicillin?
There no known serious drug interactions of isoniazid with ibuprofen, paracetamol (trade name: Tylenol), naproxen (trade name: Aleve), amoxicillin or any active drug present in Nyquil or Mucinex. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Q. Does Isoniazid cause weight loss/weight gain/hair loss/diarrhea/affect menstruation?
Changes in body weight (gain/loss), hair loss, diarrhea or changes in menstruation are not among the known side effects of Isoniazid. You may experience few of these side effects while on multi drug (including Isoniazid) treatment for tuberculosis
Q. Does Isoniazid cause acne/make you tired/cause constipation?
You may experience unusual tiredness, constipation or acne while on treatment with Isoniazid. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Q. Does Isoniazid affect birth control?
Isoniazid has no known interaction with commonly used oral contraceptives (birth control pills). However, multidrug treatment for tuberculosis contains active drug rifampin that decreases the effectiveness of oral contraceptives and hampers birth control.

Ethambutol

Q. My child vomited after taking Ethambutol. What should be done?
If your child vomited within 30 minutes of taking Ethambutol, give the same dose again. If vomiting occurred 30 minutes after taking Ethambutol, you need not repeat the dose. If your child vomits again after taking Ethambutol, consult your doctor.
Q. For how long does Ethambutol stay in your system?
Ethambutol stays for about 24 hours in your system. This duration varies from person to person and maybe different for patients with kidney problems.
Q. Will Ethambutol work if I have developed tuberculosis for the second time?
Yes, it will work if you had taken proper treatment and got cured when you developed tuberculosis for the first time. If you have any doubt, ask your doctor.
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Q. Is it necessary to take so many TB drugs simultaneously? Is there no single medicine which can provide a cure for tuberculosis?
Yes, it is important that you take all the prescribed TB drugs together for the recommended duration, else you will not be cured. A single drug is not prescribed to treat TB because it may increase the risk of developing multi-drug resistant tuberculosis, which is very difficult to treat.
Q. What is drug resistance? Can I become resistant to Ethambutol?
Sometimes it happens that bacteria gets modified in your body and stops reacting to the medicine. As a result, the medicine stops working. This is called drug resistance. Drug resistance is uncommon if Ethambutol is used in combination with other TB drugs.
Q. Can Ethambutol treatment be taken for more than two months?
Yes, Ethambutol can be continued for more than 2 months, depending on your condition and as per your doctor’s advice. If after 2 months, your investigations show that the TB bacteria are still active, you may have to take Ethambutol for 1 more month. In case you are resistant to other TB drugs, you may have to take Ethambutol and other TB drugs (for which you are not drug resistant) for longer than 2 months.
Q. What are the warning signals which should prompt me to stop taking Ethambutol?
You should consult your doctor and consider stopping the medicine immediately if you develop any vision problems like blurred vision, color blindness or any kidney problems like decreased amount of urine and swelling of your legs and feet. You may even develop liver troubles like nausea, vomiting and yellowish color of skin and eyes. Beware of all these symptoms and consult your doctor immediately.

Content on this page was last updated on 21 December, 2023, by Dr. Varun Gupta (MD Pharmacology)