Amnurite P 10mg/75mg Tablet

Tablet
Rs.193for 1 strip(s) (10 tablets each)
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Composition FOR Amnurite P

Amitriptyline(10mg),Pregabalin(75mg)

food interaction for Amnurite P

alcohol interaction for Amnurite P

pregnancy interaction for Amnurite P

lactation interaction for Amnurite P

food
alcohol
pregnancy
lactation
Amnurite P 10mg/75mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
None
CAUTION
It is unsafe to consume alcohol with Amnurite P 10mg/75mg Tablet.
UNSAFE
Amnurite P 10mg/75mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Amnurite P 10mg/75mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Amnurite P

Amitriptyline(10mg)

Uses

Amitriptyline is used in the treatment of depression, neuropathic pain and migraine.

How it works

Amitriptyline contains Amitriptyline, a tricyclic antidepressant. It has anticholinergic and sedative properties. It prevents the reuptake, and hence the inactivation of neurotransmitters called noradrenaline and serotonin, that are present at the nerve terminals in our brain. Reuptake prevention of these monoamine neurotransmitters potentiate their action in the brain. This appears to be associated with the antidepressant activity and helps in regulating the mood. It also stops the transmission of pain signals from nerves to the brain thereby relieving neuropathic pain (pain from damaged nerves).

Common side effects

Constipation, Dryness in mouth, Orthostatic hypotension (sudden lowering of blood pressure on standing), Weight gain, Aggressive behavior, Nasal congestion (stuffy nose), Sleepiness, Dizziness, Headache, Decreased libido, Nausea, Fatigue, Confusion, Tremors, Speech disorder, Palpitations, Taste change, Paresthesia (tingling or pricking sensation), Abnormality of voluntary movements, Loss of accommodation, Atrioventricular block, Micturition disorders, Erectile dysfunction, Abnormal ECG, Decreased sodium level in blood, Facial swelling, Hypomania, Mania, Anxiety, Insomnia (difficulty in sleeping), Convulsion, Ringing in ear, Rash, Liver impairment, Akathisia (inability to stay still), Suicidal thoughts, Arrhythmia (irregular heartbeats), Hair loss
Pregabalin(75mg)

Uses

Pregabalin is used in the treatment of neuropathic pain, fibromyalgia and epilepsy/seizures.

How it works

Pregabalin is an antiepileptic medication. When given for epilepsy, it is believed to work by reducing the abnormal electrical activity in the brain, thus preventing seizures. It is also used to treat nerve pain where it blocks pain by interfering with pain signals travelling through the damaged nerves and the brain. For treatment of anxiety, it is believed to work by stopping the release of certain chemical messengers (neurotransmitters) that make you feel anxious.

Common side effects

Sleepiness, Weight gain, Dryness in mouth, Blurred vision, Dizziness, Headache, Peripheral edema, Fluctuating blood pressure, Hypoglycemia (low blood glucose level), Gastrointestinal intolerance, Low blood platelets, Abnormal gait, Joint pain, Visual disturbance, Nasopharyngitis (inflammation of the throat and nasal passages), Bronchitis (inflammation of the airways), Anaphylactic reaction, Abnormal ECG, Stevens-Johnson syndrome, Heart failure, Blood cell abnormalities, Increased creatine phosphokinase (CPK) level in blood, Infection, Gastrointestinal disturbance

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Expert advice FOR Amnurite P

  • It may take 4 to 6 weeks for Amitriptyline to start working. Keep taking it as prescribed.
  • It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Amitriptyline as it may cause excessive sleepiness.
  • Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
  • It may cause sudden drop in your blood pressure. Rise slowly if you have been sitting or lying down.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed.

Frequently asked questions FOR Amnurite P

Amitriptyline

Q. What other lifestyle changes should I make to get maximum benefit of Amitriptyline?
Antidepressants, including Amitriptyline, are just one of several approaches to treat depression. Certain lifestyle changes can help you get maximum benefit of Amitriptyline and help you recover fast. Keeping active and eating a healthy diet can make a significant difference to how quickly you recover from depression. Think positively and try to discuss your thoughts with others to reduce stress. Practice yoga or take up a hobby. Ensure that you have a sound sleep to calm your mind. Stay away from smoking or alcohol consumption as these will only worsen your depression. Take your medicines as prescribed even if you start feeling better.
Q. I have been prescribed Amitriptyline for pain. When will I start feeling better?
You may start feeling better after 2 weeks of starting Amitriptyline. However, it may take 4-6 weeks to see the full benefits of the medicine.
Q. Can I stop taking Amitriptyline when my pain is relieved?
No, do not stop taking Amitriptyline even if the pain is relieved. You should use Amitriptyline as advised by the doctor. Stopping the medicine suddenly may cause unpleasant symptoms like headache, feeling unwell, sleeplessness and irritability. Consult your doctor for the duration of the treatment since the dose of Amitriptyline needs to be reduced gradually.
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Q. Is there anything I need to be careful about while on therapy with Amitriptyline?
Amitriptyline may cause drowsiness and dizziness, especially in the beginning of the treatment. So, avoid driving or using machinery until you know how the medicine affects you. Also, it is not advisable to drink alcohol during treatment with this medicine as it might increase sleepiness.
Q. Can the use of Amitriptyline affect my sex life?
Yes, Amitriptyline can affect sex life in both men and women. It may cause decreased sexual desire or you may experience discomfort during intercourse. Men may experience inability to develop or maintain an erection during sexual activity and may be unable to have an orgasm. If you notice these symptoms, do not stop taking the medicine but consult your doctor.
Q. I have been taking Amitriptyline for depression since a week and recently I have been wanting to harm myself. What should I do? Is it because of the medicine?
You should immediately consult your doctor or go to the hospital. Your suicidal tendencies may have increased because of your disease or the medicine. Generally, Amitriptyline takes about 2 weeks to show its effect but may take longer. Therefore, when you start taking Amitriptyline, you may have thoughts about killing or harming yourself. This is more common in people who previously had suicidal tendencies or are young adults (less than 25 years old). However, the effect of medicine is different for every individual.
Q. Can Amitriptyline cause urinary problems?
Yes, Amitriptyline can cause urinary problems. It is more commonly seen in elderly patients who are more than 65 years old. The patient may face difficulty in passing urine which can further lead to a urinary tract infection. Consult your doctor immediately if you develop these symptoms.
Q. If my pain is not relieved, can I take more than the recommended dose?
No, you should use Amitriptyline strictly as prescribed by the doctor. If the dose exceeds, you may develop drowsiness, confusion, difficulty in speech, dry mouth, tiredness, difficulty in walking, fever, difficulty in breathing, blue discoloration of the skin and decreased heartbeat. Your pain may not be relieved because Amitriptyline takes about 2 weeks to show its effect, but it may take longer in some cases. The duration of treatment can differ from individual to individual. Consult your doctor if your symptoms are not relieved.
Q. Does Amitriptyline cause any effect on pregnancy or the newborn?
Do not take Amitriptyline during pregnancy unless recommended by the doctor. If you take this medicine during the last trimester of the pregnancy, the newborn may develop symptoms such as irritability, rigidity, irregular body movements, irregular breathing, poor drinking, loud crying, difficulty in urinating and constipation.
Q. How long does Amitriptyline take to work?
You may see an improvement in your symptoms after a couple of weeks, although it usually takes between 4 and 6 weeks before you feel the benefits. Do not stop taking Amitriptyline after 1 or 2 weeks just because you feel it is not helping your symptoms. Give the medicine at least 6 weeks to work.
Q. How will Amitriptyline make me feel?
Antidepressants like Amitriptyline help to gradually lift your mood. You may notice that you sleep better and are less anxious. You may worry less about little things that used to bother you. Amitriptyline will not make you feel excessively or unusually happy. It will help you feel like yourself again.

Pregabalin

Q. What is Pregabalin and what is it used for?
Pregabalin belongs to the anticonvulsants class of medicines. It is used to treat seizures. It is also helpful in treating nerve pain (neuropathic pain) which could be due to diabetes, shingles, or injury. It is also used in fibromyalgia (a long-lasting condition that may cause pain, tiredness, muscle stiffness and tenderness as well as difficulty falling or staying asleep. In some cases, your doctor may prescribe this medicine for the treatment of anxiety.
Q. Pregabalin has varied roles. Does it work in the same way for each disease?
No, Pregabalin works in different ways for different diseases. In epilepsy, it stops seizures by reducing the abnormal electrical activity in the brain. In chronic pain, it blocks pain messages travelling from brain to spine.
Q. I have been prescribed Pregabalin for pain due to shingles. When can I expect relief from pain?
It may take a few weeks to see full benefits while taking Pregabalin. However, people have experienced relief from pain after a week of starting Pregabalin.
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Q. How long do I need to take Pregabalin?
Duration for the use of Pregabalin depends on the condition for which you are taking this medicine. If you are taking it for epilepsy, and it is effectively helping you then, you may have to continue it for years. If you are taking it for neuropathic or fibromyalgia pain, it is likely that once your symptoms improve you will have to continue taking it for several months. This will ensure that the problem does not come back. It is advised not to stop taking this medicine without consulting your doctor.
Q. Is it necessary to continue taking Pregabalin even if I feel fine?
Yes, you should not stop taking Pregabalin even if you feel fine. If you are taking it for epilepsy and stop its consumption suddenly, you may have seizures that will not stop. Stopping it suddenly may result in withdrawal symptoms and you may experience anxiety, difficulty in sleeping, feeling sick, pain and sweating. These can be prevented if the dose of Pregabalin is reduced gradually.
Q. Is Pregabalin addictive?
Addiction to Pregabalin is more common in people who take it for unauthorized reasons. Taking Pregabalin more than the recommended doses or taking it for long periods of time may also cause addiction. In addition to that, any person who has a history of drug abuse should never use Pregabalin. In case you feel you are becoming physically dependent on Pregabalin, inform your doctor immediately.
Q. Can I take Diazepam and Pregabalin together?
Yes, Pregabalin and Diazepam can be used together. But, there might be a chance of increased side effects since both these medicines act on the brain to depress excessive activity.
Q. Can the use of Pregabalin cause weight gain?
Yes, Pregabalin may cause weight gain because it increases your hunger. Regular physical exercise and a balanced diet with low-calorie food may help you keep your weight stable. Consult a dietician if you have any further concerns to keep your weight stable.

Content on this page was last updated on 03 April, 2024, by Dr. Varun Gupta (MD Pharmacology)