Pregabalin

Information about Pregabalin

Pregabalin uses

Pregabalin is used in the treatment of neuropathic pain, fibromyalgia and epilepsy/seizures.

How pregabalin works

Pregabalin is an antiepileptic medication. When given for epilepsy, it is believed to work by reducing the abnormal electrical activity in the brain, thus preventing seizures. It is also used to treat nerve pain where it blocks pain by interfering with pain signals travelling through the damaged nerves and the brain. For treatment of anxiety, it is believed to work by stopping the release of certain chemical messengers (neurotransmitters) that make you feel anxious.

Common side effects of pregabalin

Sleepiness, Weight gain, Dryness in mouth, Blurred vision, Dizziness, Headache, Peripheral edema, Fluctuating blood pressure, Hypoglycemia (low blood glucose level), Gastrointestinal intolerance, Low blood platelets, Abnormal gait, Joint pain, Visual disturbance, Nasopharyngitis (inflammation of the throat and nasal passages), Bronchitis (inflammation of the airways), Anaphylactic reaction, Abnormal ECG, Stevens-Johnson syndrome, Heart failure, Blood cell abnormalities, Increased creatine phosphokinase (CPK) level in blood, Infection, Gastrointestinal disturbance

Available Medicine for Pregabalin

  • ₹884 to ₹1153
    Pfizer Ltd
    2 variant(s)
  • ₹68 to ₹365
    Torrent Pharmaceuticals Ltd
    11 variant(s)
  • ₹129 to ₹340
    Sun Pharmaceutical Industries Ltd
    6 variant(s)
  • ₹30 to ₹415
    Intas Pharmaceuticals Ltd
    11 variant(s)
  • ₹165 to ₹349
    Torrent Pharmaceuticals Ltd
    5 variant(s)
  • ₹155 to ₹295
    Sun Pharmaceutical Industries Ltd
    5 variant(s)
  • ₹101 to ₹205
    La Renon Healthcare Pvt Ltd
    5 variant(s)
  • ₹80 to ₹340
    Icon Life Sciences
    5 variant(s)
  • ₹143 to ₹353
    Unichem Laboratories Ltd
    4 variant(s)
  • ₹141 to ₹226
    Micro Labs Ltd
    3 variant(s)

Expert advice for Pregabalin

  • Pregabalin should be taken as per the dose and duration prescribed by your doctor. 
  • It may cause sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • It may cause blurring or loss of vision. Inform your doctor immediately if you notice any vision changes.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • Do not stop taking the medication suddenly without talking to your doctor as it may worsen your underlying condition.

Frequently asked questions for Pregabalin

Pregabalin

Q. What is Pregabalin and what is it used for?
Pregabalin belongs to the anticonvulsants class of medicines. It is used to treat seizures. It is also helpful in treating nerve pain (neuropathic pain) which could be due to diabetes, shingles, or injury. It is also used in fibromyalgia (a long-lasting condition that may cause pain, tiredness, muscle stiffness and tenderness as well as difficulty falling or staying asleep. In some cases, your doctor may prescribe this medicine for the treatment of anxiety.
Q. Pregabalin has varied roles. Does it work in the same way for each disease?
No, Pregabalin works in different ways for different diseases. In epilepsy, it stops seizures by reducing the abnormal electrical activity in the brain. In chronic pain, it blocks pain messages travelling from brain to spine.
Q. I have been prescribed Pregabalin for pain due to shingles. When can I expect relief from pain?
It may take a few weeks to see full benefits while taking Pregabalin. However, people have experienced relief from pain after a week of starting Pregabalin.
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Q. How long do I need to take Pregabalin?
Duration for the use of Pregabalin depends on the condition for which you are taking this medicine. If you are taking it for epilepsy, and it is effectively helping you then, you may have to continue it for years. If you are taking it for neuropathic or fibromyalgia pain, it is likely that once your symptoms improve you will have to continue taking it for several months. This will ensure that the problem does not come back. It is advised not to stop taking this medicine without consulting your doctor.
Q. Is it necessary to continue taking Pregabalin even if I feel fine?
Yes, you should not stop taking Pregabalin even if you feel fine. If you are taking it for epilepsy and stop its consumption suddenly, you may have seizures that will not stop. Stopping it suddenly may result in withdrawal symptoms and you may experience anxiety, difficulty in sleeping, feeling sick, pain and sweating. These can be prevented if the dose of Pregabalin is reduced gradually.
Q. Is Pregabalin addictive?
Addiction to Pregabalin is more common in people who take it for unauthorized reasons. Taking Pregabalin more than the recommended doses or taking it for long periods of time may also cause addiction. In addition to that, any person who has a history of drug abuse should never use Pregabalin. In case you feel you are becoming physically dependent on Pregabalin, inform your doctor immediately.
Q. Can I take Diazepam and Pregabalin together?
Yes, Pregabalin and Diazepam can be used together. But, there might be a chance of increased side effects since both these medicines act on the brain to depress excessive activity.
Q. Can the use of Pregabalin cause weight gain?
Yes, Pregabalin may cause weight gain because it increases your hunger. Regular physical exercise and a balanced diet with low-calorie food may help you keep your weight stable. Consult a dietician if you have any further concerns to keep your weight stable.

Content on this page was last updated on 03 April, 2024, by Dr. Varun Gupta (MD Pharmacology)