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Amfosted 500 Injection

Injection
Rs.4133for 1 vial(s) (1 Injection each)
1
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Composition FOR Amfosted 500mg Injection

Amifostine(500mg)

food interaction for Amfosted Injection

alcohol interaction for Amfosted Injection

pregnancy interaction for Amfosted Injection

lactation interaction for Amfosted Injection

food
alcohol
pregnancy
lactation
No interaction found/established
It is not known whether it is safe to consume alcohol with Amfosted 500 Injection. Please consult your doctor.
CONSULT YOUR DOCTOR
Amfosted 500 Injection is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
UNSAFE
Information regarding the use of Amfosted 500 Injection during breastfeeding is not available. Please consult your doctor.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Amfosted 500mg Injection

Amifostine(500mg)

Amfosted injection uses

{med_name} is used to prevent dryness in the mouth after radiotherapy of head and neck cancer. It is also used to reduce the harmful effect of chemotherapy on the kidneys during treatment with cisplatin.

How amfosted injection works

Amfosted 500 Injection works by removing free radical, harmful elements produced by cisplatin (a medicine used to treat cancer) or radiation therapy in tissues.

Common side effects of amfosted injection

Hypotension (low blood pressure)

SUBSTITUTES FOR Amfosted Injection

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Expert advice FOR Amfosted Injection

  • Amifostine is given as an infusion into the vein ( IV infusion) under the supervision of a doctor only.
  • It is advisable to stay hydrated or drink plenty of fluids before taking medicine.
  • You will be monitored for blood pressure before and after every 5 minutes of infusion.
  • It may cause a decrease in calcium levels. Your doctor may monitor your calcium levels regularly and prescribe supplements if needed.

Frequently asked questions FOR Amfosted 500mg Injection

Amifostine

Q. What is Amfosted 500 Injection used for?
Amfosted 500 Injection is used to protect healthy tissues from certain side effects of cancer treatment. It may help reduce kidney damage caused by cisplatin chemotherapy and prevent moderate to severe dry mouth in selected patients receiving radiotherapy for head and neck cancer.
Q. How is Amfosted 500 Injection given?
Amfosted 500 Injection is given as an injection into a vein by a healthcare professional. It is administered before the scheduled chemotherapy or radiotherapy session, depending on the reason for treatment.
Q. Why is my blood pressure monitored during Amfosted 500 Injection infusion?
Amfosted 500 Injection can cause a sudden fall in blood pressure. Your blood pressure may be checked before, during and after the infusion to identify and manage this reaction promptly.
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Q. Why should I drink fluids before receiving Amfosted 500 Injection?
Adequate hydration helps reduce the risk of low blood pressure during the infusion. Your healthcare team will assess your fluid status and advise you on how much fluid you should receive, particularly if you have heart or kidney problems.
Q. Can Amfosted 500 Injection affect calcium levels?
Yes. Amfosted 500 Injection may lower the calcium level in your blood. Your doctor may monitor your calcium levels, particularly if you receive repeated doses or have other risk factors. Calcium supplements may be prescribed if needed.
Q. Can Amfosted 500 Injection cause nausea and vomiting?
Yes. Nausea and vomiting are common side effects and may sometimes be severe. Your doctor may give you medicines to prevent or control them before the infusion.
Q. Can Amfosted 500 Injection be given with blood pressure medicines?
Amfosted 500 Injection may cause a drop in blood pressure. Medicines used to treat high blood pressure may increase this risk. Inform your doctor about all medicines you take so that your treatment can be planned safely.
Q. What should I do if I feel dizzy during the Amfosted 500 Injection infusion?
Inform your healthcare professional immediately if you feel dizzy, faint or unusually weak during the infusion. These may be signs of low blood pressure. Do not try to stand or walk without assistance.
Q. What symptoms should I report immediately during or after the infusion?
Immediately inform your healthcare team if you experience severe dizziness, fainting, difficulty breathing, chest discomfort, skin rash or swelling. These may indicate a serious drop in blood pressure or an allergic reaction.

Content on this page was last updated on 04 November, 2026, by Dr. Mekhala Chandra (MD, MBBS)