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Istamet 50mg/500mg Tablet

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Rs.165for 1 strip(s) (15 tablets each)
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Composition FOR Istamet

Sitagliptin(50mg),Metformin(500mg)

food interaction for Istamet

alcohol interaction for Istamet

pregnancy interaction for Istamet

lactation interaction for Istamet

food
alcohol
pregnancy
lactation
Istamet 50mg/500mg Tablet is to be taken with food.
None
CAUTION
It is unsafe to consume alcohol with Istamet 50mg/500mg Tablet.
UNSAFE
Istamet 50mg/500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Istamet 50mg/500mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Istamet

Sitagliptin(50mg)

Uses

Sitagliptin is used in the treatment of type 2 diabetes mellitus. It is used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

How it works

Sitagliptin is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and postmeal sugar levels.

Common side effects

Headache, Nasopharyngitis (inflammation of the throat and nasal passages), Joint pain, Nausea, Diarrhea, Hypoglycemia (low blood glucose level), Conjunctivitis, Cough, Vomiting, Constipation, Pancreatic inflammation, Fatigue, Urinary tract infection, Sinus inflammation, Rash, Itching, Bullous pemphigoid
Metformin(500mg)

Uses

Metformin is used in the treatment of type 2 diabetes mellitus and polycystic ovarian syndrome (PCOS).

How it works

Metformin is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from the intestines, and increasing the body's sensitivity to insulin.

Common side effects

Diarrhea, Headache, Vomiting, Nausea, Flatulence, Indigestion, Vitamin B12 deficiency, Abdominal discomfort, Hepatitis (viral infection of liver), Drug eruptions, Lactic acidosis, Hypoglycemia (low blood glucose level)

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Expert advice FOR Istamet

  • Sitagliptin should be taken at the same time every day since this helps you remember to take it.
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety.
  • Be careful while driving or operating machinery until you know how Sitagliptin affects you.
  • Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea and/or vomiting.
  • Sitagliptin should be taken at the same time every day since this helps you remember to take it.
  • Be careful while driving or operating machinery until you know how Sitagliptin affects you.
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with this medicine.
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety.
  • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.
  • Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea and/or vomiting.
  • Monitor your blood sugar level regularly while taking this medicine.

Frequently asked questions FOR Istamet

Sitagliptin

Q. Does Sitagliptin cause weight gain?
No, Sitagliptin is not known to cause weight gain by itself. However, keeping a healthy weight is an important part of managing diabetes. Consult your doctor if you experience weight gain while taking Sitagliptin.
Q. Is Sitagliptin bad for your kidneys?
No, Sitagliptin is not bad for your kidneys if your kidney function is normal. However, it is important to inform your doctor if you have, or ever had, any kidney problems. If you have kidney problems, you may need dose modification.
Q. Do I still have to manage my diet and exercise while on Sitagliptin?
Yes, it is important to manage your diet and exercise while taking Sitagliptin. In addition to medicine, making healthy food choices and being physically active are also important to effectively manage blood sugar levels. You may consult a dietitian and follow a diet chart that suits you best. A well-balanced diet is one part of a healthy lifestyle for people with type 2 diabetes. Additionally, thirty minutes of exercise such as a brisk walk is recommended.
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Q. Can my blood sugar levels go too low on Sitagliptin?
Yes, it is possible that your blood sugar levels may become very low (hypoglycemia). The chances are higher if you are on any other antidiabetic medicine or insulin along with Sitagliptin. Additionally, blood sugar levels can take a huge dip if you skip meals, exercise more than usual, or if you have taken an overdose of Sitagliptin. If you experience a sudden fall in your sugar levels, inform your doctor. The doctor may suggest dose modification to prevent your blood sugar levels from decreasing significantly (hypoglycemia). Follow your doctor’s advice and monitor your blood sugar levels regularly.
Q. What is the most important information I should know about Sitagliptin?
Sitagliptin is safe to use if taken in the dose and duration prescribed by the doctor. However, in rare cases, some serious side effects can also be observed. In some people, Sitagliptin may cause inflammation of the pancreas (pancreatitis) which could be severe and can even lead to death. If you experience severe and persistent pain in your stomach area (abdomen), stop the medication and immediately contact your doctor. Sitagliptin can also cause heart failure. This means the heart is not able to pump blood well enough, therefore, inform your doctor if you have or ever had heart problems before you start taking Sitagliptin. In addition to that, problems related to kidneys should also be discussed with the doctor.
Q. How long do I need to take Sitagliptin?
Sitagliptin only helps to manage your blood sugar levels but does not cure your diabetes. Keep taking Sitagliptin as long as your doctor recommends it. You may have to take it lifelong. It is important to keep your blood sugar levels under control as any fluctuations in your blood sugar levels may cause serious problems. Therefore, do not stop taking it without talking to your doctor.
Q. What if I miss a dose of Sitagliptin?
If you miss a dose, take it as soon as you remember. If in case you do not remember until it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not take two doses of Sitagliptin at the same time.
Q. Is Sitagliptin safe to be taken for a long term?
Yes, it is safe to take Sitagliptin for a long time. Its long-term use, which can continue for months, years or even lifelong, has not shown any harmful effects. Keep taking Sitagliptin as long as your doctor recommends it. Remember, Sitagliptin only helps to keep your blood sugar levels under control but does not cure your diabetes.
Q. What will happen if I accidentally take more than the prescribed dose of Sitagliptin?
If you have accidentally taken more than the prescribed dose of Sitagliptin, your blood sugar levels may become too low (hypoglycemia). This hypoglycemia may be mild or severe. Monitor your blood sugar levels more frequently for the next 24 hours. Mild episodes of hypoglycemia (with symptoms like anxiety, sweating, weakness, tremors, fast heartbeat) can usually be corrected with the help of sugary foods such as sugar or glucose candy, fruit juice and glucose/glucon-D. However, it is important to consult your doctor to decide the further course of treatment. More severe episodes of hypoglycemia may even lead to a seizure (fit) or unconsciousness. This can be life-threatening and immediate medical help may be required.

Metformin

Q. What does Metformin do exactly?
People with type 2 diabetes are not able to make enough insulin or respond normally to the insulin made by their bodies. When this happens, the concentration of sugar/glucose increases in the blood. Metformin acts in several ways to reduce the increased levels of sugar in blood. Metformin decreases glucose production from the liver and decreases absorption of glucose from the intestine after taking food while improving the sensitivity of the body organs and muscles towards insulin. This helps improve the uptake of glucose from the blood. It also helps your body to respond better to the insulin it makes naturally.
Q. Does Metformin cause weight loss?
Yes, Metformin has been shown to cause weight loss in people who are overweight or obese. It may also cause a modest loss in weight in those overweight and obese individuals who are at risk for diabetes. In addition, patients who are sensitive or resistant to insulin may also show weight loss. But, do not start taking this medicine for weight loss on your own. Consult your doctor for the same.
Q. What are the benefits of taking Metformin?
Metformin is one of the first medicines that is given to patients with high blood sugar levels. It helps control blood sugar levels. It promotes the body’s response to the insulin made by the pancreas, decreases the amount of sugar made by the liver and decreases the amount of sugar absorbed by the intestines. Unlike other oral antidiabetic medicines, Metformin when taken alone, rarely causes low blood sugar as it prevents the pancreas from secreting more insulin. In addition to being a great medicine to lower blood sugar levels, it also helps in controlling weight gain.
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Q. Can Metformin make you sleepy?
Metformin usually does not cause sleepiness and is well tolerated. However, the use of Metformin may rarely cause sleep disorders and insomnia. Sleepiness may be due to a very serious side effect called lactic acidosis, which particularly occurs if your kidneys are not working properly. Contact your doctor if you feel sleepy or tired while taking Metformin.
Q. How to take Metformin?
Take Metformin with or after a meal. Do not crush or chew the tablets and swallow it with a glass of water. If your doctor has prescribed one tablet a day, prefer taking it in the morning with breakfast. If you have been prescribed two tablets a day, then take one in the morning and other in the evening with dinner. In case of three doses a day, apart from morning and evening, you can take it with lunch. Taking Metformin with meals will reduce its digestive problems like indigestion, nausea, vomiting, diarrhea, stomach ache and loss of appetite.

Content on this page was last updated on 18 December, 2024, by Dr. Varun Gupta (MD Pharmacology)