Q. What is the difference between Xopi 40mg Injection and ketoprofen?
Both Xopi 40mg Injection and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Xopi 40mg Injection. Ketoprofen gel also showed excellent tolerability.
Q. What is the difference between Xopi 40mg Injection and tramadol?
Xopi 40mg Injection is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Q. What is the difference between Xopi 40mg Injection and nimesulide?
Both Xopi 40mg Injection and nimesulide are pain killers. However, Xopi 40mg Injection is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Q. Can Xopi 40mg Injection be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Xopi 40mg Injection or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Xopi 40mg Injection.
Q. Are Xopi 40mg Injection and aspirin same?
No. Xopi 40mg Injection and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Q. Can Xopi 40mg Injection be used along with dexamethasone?
No. Xopi 40mg Injection should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Q. Can Xopi 40mg Injection be used with methocarbamol?
Yes. Methocarbamol can be used with Xopi 40mg Injection as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Can Xopi 40mg Injection be used along with paracetamol?
Yes. Paracetamol can be used with Xopi 40mg Injection as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Is Xopi 40mg Injection a NSAID?
Yes. Xopi 40mg Injection is a non-steroidal anti-inflammatory drug (NSAID).
Q. Is Xopi 40mg Injection a sulfa drug?
Xopi 40mg Injection is a sulphur containing compound. Xopi 40mg Injection can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Q. Is Xopi 40mg Injection a blood thinner?
No. Xopi 40mg Injection is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Q. Is Xopi 40mg Injection a muscle relaxant?
No. Xopi 40mg Injection is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Q. Is Xopi 40mg Injection a narcotic?
No. Xopi 40mg Injection is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Q. Can Xopi 40mg Injection be used in hypertension?
No. Xopi 40mg Injection is not a medication to control hypertension. It is important to note that Xopi 40mg Injection decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Xopi 40mg Injection.
Q. Can Xopi 40mg Injection be used along with Losartan?
No. Xopi 40mg Injection should not be combined with Losartan. It is important to note that Xopi 40mg Injection decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Xopi 40mg Injection.
Q. Can Xopi 40mg Injection be used with Lisinopril?
No. Xopi 40mg Injection should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Xopi 40mg Injection.
Q. Can Xopi 40mg Injection be used with calcium channel blocker?
Yes. Xopi 40mg Injection can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Q. Can Xopi 40mg Injection be used with Tizanidine?
Yes, Xopi 40mg Injection can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Q. Why is beta cyclodextrin added to Xopi 40mg Injection?
Yes. Xopi 40mg Injection can be combined with beta-cyclodextrin. Research has shown that combining Xopi 40mg Injection with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Q. Are there any alternatives of Xopi 40mg Injection?
Yes. There are alternatives to Xopi 40mg Injection. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Q. What are the contraindications for Xopi 40mg Injection?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Q. Can Xopi 40mg Injection be used in the treatment of allergy?
No. Xopi 40mg Injection is not a drug to treat allergy. It is a pain killer.
Q. How long does Xopi 40mg Injection work?
Xopi 40mg Injection is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Q. Can you get high by using Xopi 40mg Injection?
No. Xopi 40mg Injection is not known to cause high. It is a non-narcotic painkiller.
Q. Can Xopi 40mg Injection be used to treat menstrual cramp?
Xopi 40mg Injection is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Q. Can I use Xopi 40mg Injection for a migraine?
Xopi 40mg Injection is not approved for the treatment of migraine. Research studies have shown that Xopi 40mg Injection is effective in significantly decreasing the pain associated with migraine without aura.
Q. Is Xopi 40mg Injection effective in back pain management?
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Xopi 40mg Injection as the cause of back pain can be different for different person.
Q. Is Xopi 40mg Injection affective in gout management?
Yes. Xopi 40mg Injection can be given for the treatment of acute gout. Research studies have shown Xopi 40mg Injection to be highly effective in the treatment of acute gout.
Q. Can you donate blood when on the medication with Xopi 40mg Injection?
Yes. You can donate blood when on Xopi 40mg Injection. Do inform your doctor before donating blood.
Q. Can I use Xopi 40mg Injection if I am a diabetic?
Xopi 40mg Injection in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Xopi 40mg Injection so taking piroxicam can lead to increased risk of renal failure by many folds.
Q. Can I use Xopi 40mg Injection if I have a deranged renal function?
No. Xopi 40mg Injection should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Q. Can Xopi 40mg Injection lead to skin reactions?
Yes. Xopi 40mg Injection is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Q. Can I use Xopi 40mg Injection if I am pregnant?
No. Xopi 40mg Injection should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Q. Can I use Xopi 40mg Injection if I have peptic ulcer disease?
No. Xopi 40mg Injection is contraindicated in cases of active peptic ulcer disease. Xopi 40mg Injection is known to cause gastric ulceration and bleeding.
Q. Can I use Xopi 40mg Injection if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. Can Xopi 40mg Injection lead to difficulty in conception?
Yes. Xopi 40mg Injection can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Can Xopi 40mg Injection be used with diuretics?
No. Xopi 40mg Injection should not be used with diuretics. Xopi 40mg Injection reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can Xopi 40mg Injection be used with lithium?
No. Xopi 40mg Injection should not be used with lithium. Xopi 40mg Injection leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Q. Can Xopi 40mg Injection be used with warfarin?
No. Xopi 40mg Injection should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Q. What increases the chances of getting a gastric ulcer when I am already taking Xopi 40mg Injection?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Xopi 40mg Injection?
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Q. What are the serious side effects of Xopi 40mg Injection?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
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