Vinblastine

Information about Vinblastine

Vinblastine uses

Vinblastine is used in the treatment of non-Hodgkin lymphoma (NHL), breast cancer, kidney cancer and Hodgkin’s disease.

How vinblastine works

Vinblastine blocks replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells.

Common side effects of vinblastine

Nausea, Vomiting, Decreased appetite, Diarrhea, Low blood platelets, Hair loss, Anemia (low number of red blood cells), Constipation, Decreased white blood cell count (lymphocytes), High blood pressure, General discomfort, Bone pain, Tumor pain, Jaw pain, Myocardial infarction, Angina pectoris, Abnormal ECG, Photosensitivity, Vesiculation of the mouth, Pharyngitis, Hemorrhagic enterocolitis, Perforated peptic ulcer, Rectal bleeding, Paresthesia (tingling or pricking sensation), Vestibular damage, Hearing loss, Loss of deep-tendon reflexes, Peripheral neuritis, Shortness of breath, Bronchospasm, Depression, Headache, Convulsion

Available Medicine for Vinblastine

Expert advice for Vinblastine

  • Vinblastine is given as an IV infusion or injection into a vein under the supervision of a doctor.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor your blood cell count, platelet count, uric acid level and liver function.
  • Inform your doctor if you experience a skin rash, swelling of face or lips and trouble breathing.
     

Frequently asked questions for Vinblastine

Vinblastine

Q. Is Vinblastine a vesicant?
Vinblastine is a vesicant (irritant) and can cause damage to the blood vessels if it is not administered properly.
Q. How is Vinblastine administered?
Vinblastine is administered by intravenous route only.
Q. Does Vinblastine cause hair loss/infertility?
Yes, Vinblastine may cause hair loss/infertility.
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Q. How does Vinblastine prevent mitosis?
Vinblastine prevents mitosis by inhibition of microtubule formation.

Content on this page was last updated on 26 August, 2022, by Dr. Varun Gupta (MD Pharmacology)