Sertraline

Information about Sertraline

Sertraline uses

Sertraline is used in the treatment of depression, post traumatic stress disorder, obsessive-compulsive disorder, Panic disorder, Premenstrual dysphoric disorder, Anxiety and Premenstrual syndrome (PMS).

How sertraline works

Sertraline is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms of depression and also relieves symptoms of obsessive-compulsive disorder, panic disorder, premenstrual dysphoric disorder, and anxiety.

Common side effects of sertraline

Insomnia (difficulty in sleeping), Nausea, Diarrhea, Tremors, Abdominal pain, Decreased libido, Dizziness, Ejaculation disorder, Headache, Sleepiness, Agitation, Weight loss, Palpitations, High blood pressure, Dyslipidemia, Neuropsychiatric symptoms, Increased liver enzymes, Menstrual disorder, Dilatation of pupil, Respiratory disorder, Diabetes, Blood circulation disorder, Lymphatic system abnormalities, Joint pain, Nosebleeds

Available Medicine for Sertraline

  • ₹43 to ₹335
    Torrent Pharmaceuticals Ltd
    4 variant(s)
  • ₹63 to ₹310
    Pfizer Ltd
    5 variant(s)
  • ₹69 to ₹193
    Eris Lifesciences Ltd
    3 variant(s)
  • ₹74 to ₹207
    Sun Pharmaceutical Industries Ltd
    3 variant(s)
  • ₹57 to ₹134
    La Renon Healthcare Pvt Ltd
    3 variant(s)
  • ₹66 to ₹177
    Intas Pharmaceuticals Ltd
    4 variant(s)
  • ₹55 to ₹140
    Talent India
    3 variant(s)
  • ₹56 to ₹146
    Shine Pharmaceuticals Ltd
    5 variant(s)
  • ₹76 to ₹138
    Torrent Pharmaceuticals Ltd
    2 variant(s)
  • ₹76 to ₹177
    Ipca Laboratories Ltd
    3 variant(s)

Expert advice for Sertraline

  • Do not drive or do anything requiring concentration until you know how Sertraline affects you.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • The addiction/dependence potential of Sertraline is very less.
  • Inform your doctor if you experience decreased sex drive or difficulty having an orgasm.
  • Do not stop taking the medication suddenly without talking to your doctor.

Frequently asked questions for Sertraline

Sertraline

Q. Does Sertraline cause weight gain?
Sertraline commonly causes weight gain as the patient is unable to stop the urge to eat. Additionally, use of Sertraline may also lead to weight loss, though it occurs rarely. The reason for weight loss could be loss of appetite. Consult your doctor in case of any concerns regarding your weight.
Q. How long does it take for Sertraline to work?
You may start noticing an improvement in symptoms within 7 days of taking Sertraline. However, it may take longer to show full response and will vary from person to person.
Q. How long do I need to take Sertraline?
You should continue taking Sertraline as long as your doctor recommends to take it which may be for several months. Doctors usually recommend the medicine for 6 months to a year after you no longer feel depressed. It is important to know that stopping the medication before the suggested time may cause depression to come back.
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Q. When is the best time to take Sertraline?
Sertraline is usually taken once a day and can be taken at any time of the day. It can be taken with or without food. Take it as per your convenience but preferably at the same time each day. Some people who have sleep difficulty after taking Sertraline, they should take it in the morning. Whereas, some take it at night to limit the side effects of nausea and vomiting.
Q. Does Sertraline cause sleepiness?
Yes, Sertraline may commonly cause sleepiness. In case you feel dizzy, sleepy or tired after taking Sertraline, you should avoid driving or using heavy machinery. This generally happens within the first few days and weeks after starting Sertraline, which may disappear after 2-3 months of use of Sertraline.
Q. What does Sertraline do for anxiety?
Sertraline belongs to selective serotonin reuptake inhibitor (SSRI) class of medicines. It increases the levels of serotonin which is an important chemical and a neurotransmitter. This increase in serotonin levels can help to improve and regulate your mood, resulting in an improvement in the symptoms of anxiety.
Q. Can I stop taking Sertraline if I am better now?
No, you should not stop taking Sertraline without consulting your doctor. This is because sudden discontinuation of Sertraline may cause withdrawal symptoms. Hence, it is important to gradually reduce the dose with time (over several weeks or months).
Q. What are the withdrawal symptoms of Sertraline?
The withdrawal symptoms of Sertraline include dizziness, nausea, numbness or tingling in the hands or feet, trouble sleeping, feeling agitated or anxious, headaches and shaking. However, these symptoms are generally mild to moderate and disappear after 1-2 weeks of discontinuing Sertraline.
Q. What are the symptoms of overdose of Sertraline?
The symptoms of overdose of Sertraline include nausea, dizziness, fever, vomiting, confusion, shakiness, and a rapid heartbeat. Whereas, serious side effects include fainting, delirium, heart problems, and changes in blood pressure. If you experience such symptoms immediately contact your doctor or seek emergency medical services in a nearby hospital.

Content on this page was last updated on 13 June, 2023, by Dr. Varun Gupta (MD Pharmacology)