Saroglitazar

Information about Saroglitazar

Saroglitazar uses

Saroglitazar is used in the treatment of Noncirrhotic Non-Alcoholic Steatohepatitis, Non-alcoholic fatty liver disease and diabetic dyslipidemia.

How saroglitazar works

Saroglitazar contains Saroglitazar, a dual action peroxisome proliferator-activated receptor (PPAR) inhibitor that aids in the management of high cholesterol, especially triglycerides, as well as blood sugar levels in people with type 2 diabetes. It acts by a unique mechanism in which it reduces the synthesis and secretion of triglycerides (a type of lipid or cholesterol in blood). It also improves insulin sensitivity of the body for better utilization of the existing insulin and hence lowers the blood sugar levels.

Common side effects of saroglitazar

Weakness, Fever, Gastritis, Headache, Chest discomfort, Oral dysesthesia, Pharyngitis, Muscle weakness, Hyperchlorhydria, Nausea

Available Medicine for Saroglitazar

  • ₹441 to ₹1989
    Zydus Cadila
    2 variant(s)
  • ₹442
    Zydus Cadila
    1 variant(s)
  • ₹441
    Lupin Ltd
    1 variant(s)
  • ₹441
    Torrent Pharmaceuticals Ltd
    1 variant(s)

Expert advice for Saroglitazar

  • Saroglitazar has beneficial effects in controlling both high cholesterol mainly triglycerides and sugar levels in diabetic patients.
  • It is best to take Saroglitazar before the first meal of the day.
  • You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Saroglitazar.

Frequently asked questions for Saroglitazar

Saroglitazar

Q. Who should not take Saroglitazar?
Saroglitazar should not be taken by people who are allergic to Saroglitazar or any of its ingredients. If you are not sure, please consult your doctor.
Q. Is there a chance of weight gain with Saroglitazar?
It has been observed from clinical research conducted on Saroglitazar that there is no significant risk of weight gain in patients taking Saroglitazar. However, if a patient experiences a rapid increase in weight, any other difficulty, or fluid accumulation in the body then it should be immediately informed to the doctor for further assessment or change of therapy.
Q. Is Saroglitazar is helpful in increasing good cholesterol?
Yes, it has been found that Saroglitazar helps improve the good cholesterol or HDL-C and at the same time helps reduce the bad cholesterol like LDL, triglycerides etc. Though the effectiveness of this medicine varies from patient to patient still it has been found to be effective in controlling the high triglyceride levels in the blood. Consult your doctor before you start taking this medication.
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Q. What other lifestyle changes should I make to manage nonalcoholic steatohepatitis (NASH)
Lifestyle changes play a major role in managing nonalcoholic steatohepatitis (NASH). A healthy body weight helps you manage this condition very effectively. Avoid taking excess salt in your diet and find ways to reduce or manage stress in your life as it increases body weight too. Practice yoga or meditation or take up a hobby. Ensure that you have a sound sleep every night as this also helps to reduce stress levels. Stop smoking and alcohol consumption. Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables and fat-free products. Consult your doctor if you need any further guidance to get the maximum benefit of Saroglitazar and to keep yourself healthy.
Q. Can I take Saroglitazar in pregnancy?
There is no clarity on the use of Saroglitazar in pregnancy and it may be unsafe to take it in pregnancy. However, if you are pregnant or planning to conceive, consult your doctor before taking Saroglitazar. You may take it only if prescribed by your doctor.
Q. Is it safe for lactating mothers to take Saroglitazar?
No, it is not safe for lactating mothers to take Saroglitazar because there is no evidence of its safety for usage during breastfeeding. The other reason for not using this medicine is that it is not known whether Saroglitazar gets excreted via breast milk. Consult your doctor before taking this medicine if you are breastfeeding to make sure there is no harm to your baby.

Content on this page was last updated on 21 June, 2021, by Dr. Varun Gupta (MD Pharmacology)