Pyrazinamide

Information about Pyrazinamide

Pyrazinamide uses

Pyrazinamide is used in the treatment of tuberculosis.

How pyrazinamide works

Pyrazinamide is an antitubercular medicine. In the body, it gets converted to pyrazinoic acid. This pyrazinoic acid inhibits fatty acid synthase I (bacterial enzyme), which is essential for bacterial growth. Thus, it works as a bacteriocidal to prohibit their growth and treats tuberculosis.

Common side effects of pyrazinamide

Hepatitis (viral infection of liver), Joint pain, Skin rash, Nausea, Vomiting, Abdominal pain, Sideroblastic anemia, Fever, General discomfort, Liver tenderness, Hepatomegaly (enlarged liver), Enlarged spleen, Decreased appetite, Flushing (sense of warmth in the face, ears, neck and trunk), Discomfort when urinating

Available Medicine for Pyrazinamide

Pyzina
₹51 to ₹111
Lupin Ltd
4 variant(s)
P Zide
₹45 to ₹97
Cadila Pharmaceuticals Ltd
4 variant(s)
Macrozide
₹26 to ₹110
Macleods Pharmaceuticals Pvt Ltd
5 variant(s)
Pza Ciba
₹10 to ₹74
Novartis India Ltd
5 variant(s)
Mzide
₹49 to ₹81
Marc Laboratories Pvt Ltd
3 variant(s)
Pyra
₹17 to ₹112
Kopran Ltd
3 variant(s)
Pyranij
₹39 to ₹62
Sunij Pharma Pvt Ltd
2 variant(s)
Pyramid
₹54 to ₹58
Que Pharma Pvt Ltd
2 variant(s)
Isomide
₹49
Zee Laboratories
1 variant(s)
Cavizide
₹31 to ₹46
Wockhardt Ltd
2 variant(s)

Expert advice for Pyrazinamide

Pyrazinamide along with other medications effectively treats tuberculosis.
Do not to forget a dose, as this increases the risk of the bacteria becoming resistant to the medicine, and also increases the risk of getting side effects.
Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Avoid drinking alcohol while taking Pyrazinamide as this may increase the risk of side effects on the liver.
Use a reliable contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking Pyrazinamide as it may make hormonal contraceptives such as the pill less effective.

Frequently asked questions for Pyrazinamide

Pyrazinamide

Q. What is Pyrazinamide and what is it used for?

Pyrazinamide is an antibiotic. It is used in combination with other antibiotics in the treatment of tuberculosis

Q. Is Pyrazinamide bactericidal?

Pyrazinamide is both a bacteriostatic and a bactericidal antibiotic. It stops the growth of bacteria (bacteriostatic) in certain cases and kills (bactericidal) the tuberculosis causing bacteria in other cases

Q. How does Pyrazinamide work/treat tuberculosis?

Pyrazinamide kills or stops growth of bacteria that causes tuberculosis (Mycobacterium tuberculosis). The exact mechanism of action for Pyrazinamide is not known