Pizotifen

Information about Pizotifen

Pizotifen uses

Pizotifen is used to prevent migraine.

How pizotifen works

Migraine headaches are thought to result from the dilatation of blood vessels in the head. Pizotifen is a serotonin antagonist. It works by maintaining the level of serotonin (chemical messenger) in the brain and also prevents loss of tone and dilation of blood vessels, thus preventing the migraine headache.

Common side effects of pizotifen

Dryness in mouth, Increased appetite, Dizziness, Drowsiness, Fatigue, Nausea, Insomnia (difficulty in sleeping), Hypersensitivity, Increase in body weight, Constipation, Paresthesia (tingling or pricking sensation), Seizure, Urticaria, Rash, Muscle pain, Joint pain, Facial swelling, Depression, CNS stimulation, Anxiety, Hallucination, Sleep disorder, Increased liver enzymes, Jaundice, Hepatitis (viral infection of liver), Muscle cramp

Available Medicine for Pizotifen

  • ₹39
    Kamron Laboratories Ltd
    1 variant(s)

Expert advice for Pizotifen

  • You have been prescribed Pizotifen for the prevention of migraine headaches.
  • Do not take it to treat an acute attack of migraine.
  • Some tips that may help avoid a migraine attack:
    • Have your meals at the same time every day
    • Avoid bright lights and extreme temperatures
    • Avoid loud music and noisy places
    • Avoid chocolates,  cheese, processed food, alcohol and smoking
    • Get sufficient sleep and avoid stress
  • It should be taken at night-time before going to bed.
  • It may cause sleepiness. Don't drive or do anything that requires mental focus until you know how Pizotifen affects you.
  • You may experience weight gain while on treatment. Monitoring of body weight is required on a regular basis.
  • Notify your doctor if you develop skin rash, muscle aches, tremors, difficulty moving, or abnormal uncontrolled movement.

Frequently asked questions for Pizotifen

Pizotifen

Q. Does Pizotifen cause weight gain?
Yes, Pizotifen causes weight gain. This is because of an increase in appetite. If there is an increase in hunger than usual, you can include fresh low-calorie foods in your diet. These are much healthier than processed high-calorie foods. Your doctor can give you advice about diet as some kind of foods are known to trigger migraine.
Q. Does Pizotifen cause dry mouth?
Yes, it may cause dry mouth because it has anti-cholinergic side effects, though these effects are relatively weak.
Q. Can Pizotifen affect blood pressure?
No, Pizotifen does not affect the blood pressure. However, if more than the recommended dose of Pizotifen is taken, low blood pressure may occur.
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Q. Does Pizotifen make you sleepy?
Yes, Pizotifen makes you sleepy, drowsy, and dizzy. Avoid driving and operating heavy machinery while using Pizotifen.
Q. What should I tell my doctor before starting Pizotifen?
Inform your doctor if you are taking any medicines. You should tell your doctor if you have glaucoma (increased pressure in the eyes), difficulty in passing urine (water) due to prostate trouble or any other cause. The doctor should also be informed if you had or have convulsions, fits, or seizures, and kidney-related problems. Let your doctor know if you are pregnant, trying to become pregnant or are breastfeeding. Any intolerance to some sugars should be told as well because Pizotifen tablets have lactose, a type of sugar.
Q. How long do I need to take Pizotifen?
Pizotifen should be taken as prescribed by the doctor. This medicine only helps to prevent migraine, it does not treat migraine attack. Do not stop the medicine and take it regularly, even if you feel well.
Q. Can I take Pizotifen with paracetamol or ibuprofen?
Yes, Pizotifen can be taken with paracetamol or ibuprofen, as it does not interfere with the working of paracetamol or ibuprofen. Similarly, these medicines do not interfere with the working of pizotifen. However, consult with your doctor before taking any medicine.
Q. What can happen if I take more than the recommended dose of Pizotifen?
If you have taken more than the recommended dose of pizotifen you may experience drowsiness, dizziness, confusion, fits or excitement (particularly in children). You may also feel difficulty in breathing or controlling movements, fast heartbeat, low blood pressure, dry mouth, feeling or being sick, blueness of the skin, coma or respiratory paralysis. Inform your doctor and seek immediate medical help.

Content on this page was last updated on 10 October, 2022, by Dr. Varun Gupta (MD Pharmacology)