Pirfenidone
Information about Pirfenidone
Pirfenidone uses
Pirfenidone is used in the treatment of idiopathic pulmonary fibrosis.
How pirfenidone works
Pirfenidone is an antifibrotic medication. It works by reducing fibrosis (scarring) and swelling in the lungs. This makes breathing easier.
Common side effects of pirfenidone
Headache, Dizziness, Insomnia (difficulty in sleeping), Loss of appetite, Weight loss, Upper respiratory tract infection, Sinus inflammation, Tiredness
Available Medicine for Pirfenidone
Expert advice for Pirfenidone
- Pirfenidone reduces scarring and swelling in the lungs, and helps you breathe better.
- It is best to take this medicine with food and at the same time each day.
- This medication may make you more sensitive to sun. Use sunscreen and wear protective clothing when outdoors.
- Stop smoking during treatment with Pirfenidone as it can reduce the effect of the treatment.
- It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
- It may cause weight loss. Monitor your weight regularly.
- Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin (jaundice).
Frequently asked questions for Pirfenidone
Pirfenidone
Q. Is Pirfenidone a steroid?
No, Pirfenidone is not a steroid. It belongs to pyridines group of medicines. It is used to treat idiopathic pulmonary fibrosis (IPF) in adults. In IPF, the tissues of the lungs get scarred and swell with time, which creates problem in breathing. This medicine helps reduce these effects to make you breathe better.
Q. What are the side effects of Pirfenidone?
Most common side effects of Pirfenidone include skin sensitivity to sunlight, nausea, tiredness, diarrhea, indigestion or upset stomach, loss of appetite, and headache. Other common side effects include infections of the throat or the airways, bladder infections, weight loss, difficulty sleeping, dizziness, sleepiness, changes in taste, hot flushes, shortness of breath, and cough. Additionally, one may experience stomach problems such as acid reflux, vomiting, bloating, abdominal pain and discomfort, heart burn, constipation, skin problems such as itchy skin, skin redness or red skin, dry skin, skin rash, muscle pain, aching joints/joint pains, weakness, chest pain, and sunburn. It is possible that after using Pirfenidone blood tests may show increased levels of liver enzymes.
Q. What monitoring will I need during treatment with Pirfenidone?
Your doctor will check your liver function before starting treatment with Pirfenidone. This test will be repeated monthly for the first 6 months and then it will be done after every three months. In addition to that, your doctor will also monitor your lung function periodically in order to see the response to Pirfenidone.