Palonosetron

Information about Palonosetron

Palonosetron uses

Palonosetron is used to prevent nausea and vomiting.

How palonosetron works

Palonosetron is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

Common side effects of palonosetron

Constipation, Headache, Diarrhea, Dizziness, Increased potassium level in blood, Metabolic disorder, Decreased calcium level in blood, Decreased potassium level in blood, Decreased appetite, Increased glucose level in blood, Anxiety, Sleepiness, Insomnia (difficulty in sleeping), Paresthesia (tingling or pricking sensation), Eye irritation, Hiccup, Dyspepsia, Abdominal pain, Dryness in mouth, Flatulence, Joint pain, Dermatitis, Rash, Itching, Urinary retention, Glycosuria, Prolonged QT interval, Shock, Injection site reactions (pain, swelling, redness)

Available Medicine for Palonosetron

  • ₹168
    Zuventus Healthcare Ltd
    1 variant(s)
  • ₹132 to ₹164
    Themis Medicare Ltd
    2 variant(s)
  • ₹96 to ₹327
    Intas Pharmaceuticals Ltd
    2 variant(s)
  • ₹113
    Ajanta Pharma Ltd
    1 variant(s)
  • ₹140
    Dr Reddy's Laboratories Ltd
    1 variant(s)
  • ₹151
    Glenmark Pharmaceuticals Ltd
    1 variant(s)
  • ₹192
    United Biotech Pvt Ltd
    1 variant(s)
  • ₹96
    Alkem Laboratories Ltd
    1 variant(s)
  • ₹140
    Sun Pharmaceutical Industries Ltd
    1 variant(s)
  • ₹149
    Lupin Ltd
    1 variant(s)

Expert advice for Palonosetron

  • You have been prescribed Palonosetron for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.
  • It comes in many different forms that do not need to be swallowed, such as a film that is placed on  the tongue or as a dissolving pill.
  • It is fast-acting and starts working within 30 minutes.
  • If you vomit within one hour of taking a dose, take another dose.
  • Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.

Frequently asked questions for Palonosetron

Palonosetron

Q. How quickly does Palonosetron work?
Palonosetron starts working within half an hour to 2 hours. It dissolves rapidly into the bloodstream and starts showing its effect.
Q. What are the side effects of Palonosetron?
The most common side effects of Palonosetron are constipation and headache. However, these are usually not bothersome and resolve on their own after sometime. If these persist or worry you, please consult your doctor.
Q. When should you take Palonosetron?
Palonosetron can be taken with or without food with a glass full of water. The first dose of Palonosetron is usually taken before the start of your surgery, chemotherapy, or radiation treatment. Follow your doctor's dosing instructions very carefully.
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Q. Is Palonosetron a steroid?
No, Palonosetron is an antiemetic and not a steroid. Palonosetron is a selective 5-HT3 receptor antagonist prescribed for the treatment of nausea and vomiting caused after a surgery or due to cancer chemotherapy.
Q. Does Palonosetron work for seasickness?
No, Palonosetron does not work for seasickness. This is because Palonosetron has very little effect on the nausea associated with motion sickness.

Content on this page was last updated on 13 June, 2023, by Dr. Varun Gupta (MD Pharmacology)