Obeticholic acid
Information about Obeticholic acid
Obeticholic acid uses
Obeticholic acid is used in the treatment of primary biliary cirrhosis.
How obeticholic acid works
Obeticholic acid stimulates Farnesoid X receptor (FXR), a chemical that regulates synthesis and transport of bile acid, lipid metabolism and regulation of glucose levels. Obeticholic acid inhibits bile acid synthesis and increases bile acid secretions. This reduces the bile acid pool in the liver and hence prevents its toxic effects. Therefore, it helps to improve liver function.
Common side effects of obeticholic acid
Itching, Fatigue, Abdominal pain, Abdominal discomfort, Rash, Joint pain, Oropharyngeal pain, Dizziness, Constipation, Peripheral edema, Palpitations, Fever, Thyroid disorders, Eczema