Nitisinone

Information about Nitisinone

Nitisinone uses

Nitisinone is used in the treatment of Hereditary Tyrosinemia Type 1.

How nitisinone works

Nitisinone works by preventing the breaking down of an amino acid called tyrosine and by keeping other toxic substances from building up and causing harm to your liver or kidneys.

Common side effects of nitisinone

Elevated tyrosine levels, Low blood platelets, Decreased white blood cell count (lymphocytes), Conjunctivitis, Corneal opacity, Corneal inflammation, Photophobia, Eye pain, Eyelid inflammation, Cataract, Granulocytopenia, Nosebleeds, Itching, Exfoliative dermatitis, Dry skin, Maculopapular rash, Hair loss

Available Medicine for Nitisinone

  • ₹30000 to ₹50000
    Laurus Labs Limited
    3 variant(s)

Expert advice for Nitisinone

  • This formulation contains glycerol and may cause headaches, upset stomach, and diarrhea. Consult your doctor if these symptoms become severe.
  • Nitisinone may cause vision problems, eye pain, eye redness, burning sensation and increased sensitivity of eyes to light. Seek immediate medical help in such cases.
  • You may be prescribed tests to monitor your platelet and white blood cell counts regularly while taking Nitisinone. 
  • Take Nitisinone on an empty stomach at least 1 hour before or 2 hours after a meal.
  • You must avoid certain foods for your treatment to be effective. Follow the diet plan created for you by your doctor.
  • If you are unable to swallow a capsule whole, open it and sprinkle the medicine into a spoonful of water. Swallow the mixture right away without chewing. Do not save it for later use.

Frequently asked questions for Nitisinone

Nitisinone

Q. Which foods are high in tyrosine and should be avoided while taking Nitisinone?
While taking Nitisinone, it is advisable to avoid tyrosine-rich foods, such as soybean, chicken, lamb, pork, fish, cheese, eggs, nuts, and beans.
Q. What is the best time to take Nitisinone?
It is advisable to take this medicine at least one hour before or two hours after a meal.
Q. Can Nitisinone cause visual disturbances?
Yes, this medicine can cause visual disturbances, and thus avoid driving or operating any machinery after consuming this drug.
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Q. I am experiencing diarrhea and stomach pain after starting the treatment with Nitisinone?
This medicine may upset the stomach and cause diarrhea due to the glycerol component of the formulation. Inform your doctor if the symptoms persist for a long or worsen.

Content on this page was last updated on 19 May, 2023, by Dr. Varun Gupta (MD Pharmacology)