Mifepristone + Misoprostol

Information about Mifepristone + Misoprostol

Mifepristone + misoprostol uses

Mifepristone+Misoprostol is used for medical abortion.

How mifepristone + misoprostol works

This is a combination of two medicines: Mifepristone and Misoprostol, which causes abortion. Mifepristone blocks the effects of progesterone, a natural female hormone that is needed for the pregnancy to sustain. Without this hormone, the lining of the uterus (womb) breaks down as it does during a menstrual period and stops the growth of the pregnancy. Misoprostol increases contractions of the uterus to cause abortion.

Common side effects of mifepristone + misoprostol

Nausea, Vomiting, Diarrhea, Weakness, Fever, Chills, Headache, Heavy bleeding, Uterine cramps, Salpingitis, Hemorrhagic shock, Skin rash, Hot flushes, Hypotension (low blood pressure), Bacterial infection, Septic shock

Available Medicine for Mifepristone + Misoprostol

  • ₹393
    Mankind Pharma Ltd
    1 variant(s)
  • ₹425 to ₹575
    Biochem Pharmaceutical Industries
    2 variant(s)
  • ₹353 to ₹476
    Aristo Pharmaceuticals Pvt Ltd
    2 variant(s)
  • ₹385 to ₹600
    Cadila Pharmaceuticals Ltd
    2 variant(s)
  • ₹424
    Macleods Pharmaceuticals Pvt Ltd
    1 variant(s)
  • ₹399
    Mankind Pharma Ltd
    1 variant(s)
  • ₹390
    Intas Pharmaceuticals Ltd
    1 variant(s)
  • ₹595
    DKT India Ltd
    1 variant(s)
  • ₹541
    Lincoln Pharmaceuticals Ltd
    1 variant(s)
  • ₹510
    Torrent Pharmaceuticals Ltd
    1 variant(s)

Expert advice for Mifepristone + Misoprostol

  • Mifepristone + Misoprostol helps terminate a pregnancy.
  • Use caution while driving or doing anything that requires concentration as it can cause dizziness and sleepiness.
  • It does not affect fertility. Use contraception to avoid pregnancy.
  • For pregnancy termination:
    • Take it no later than 63 days after the first day of your last menstrual period.
    • Take Misoprostol 36 – 48 hours after taking Mifepristone.
    • Rest for at least 3 hours after taking the Misoprostol.
    • Take it only as prescribed by the doctor. Miscarriages, if incomplete, may result in serious medical complications leading to hospitalization, surgery and possible infertility.
    • Vaginal bleeding lasting for approximately 12 days may occur after taking this medicine. Inform your doctor immediately if excessive bleeding occurs or if you suffer from severe abdominal pain.

Frequently asked questions for Mifepristone + Misoprostol

Mifepristone + Misoprostol

Q. What is Mifepristone+Misoprostol and what is it used for?
Mifepristone+Misoprostol are the medicines, used for medical termination of pregnancy. They are only used to terminate a pregnancy which should not be more than 63 days old, counting from the first day of the last menstrual period.
Q. How and in what dose should I take Mifepristone+Misoprostol?
Mifepristone+Misoprostol should only be taken as per the advice of the doctor. The course is started with Mifepristone. Misoprostol is advised after 36-48 hours of taking Mifepristone. However, Misoprostol should only be taken under the supervision of a gynecologist, at a clinic or hospital setting.
Q. What should I expect after completing my course of Mifepristone+Misoprostol?
After taking Mifepristone, you may or may not experience vaginal bleeding. However, you may experience abdominal cramping, diarrhea, stomach pain, and nausea immediately after taking Misoprostol. You may also have vaginal bleeding within 4 hours of taking Misoprostol. You may also be asked to stay at the clinic or healthcare center for at least 3 hours after taking this medicine. After 14 days of taking Mifepristone (pill you took before Misoprostol), your gynecologist may run some blood tests or perform ultrasonography to confirm whether pregnancy has been terminated or not.
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Q. Can Mifepristone+Misoprostol affect my future chances of getting pregnant?
No, studies have shown that this medicine does not impair the fertility of the women. Your future chances of getting pregnant are as equal as those who have not taken this medicine.
Q. What are the common side effects of taking Mifepristone+Misoprostol?
The common side effects of using Mifepristone+Misoprostol are abdominal pain, abdominal cramping, nausea, diarrhea, dizziness, uterine contractions, pelvic pain, and shivering. If you experience a very heavy vaginal bleeding or if any of these side effects bother you please consult with your gynecologist.

Content on this page was last updated on 12 September, 2022, by Dr. Varun Gupta (MD Pharmacology)