Lamivudine

Information about Lamivudine

Lamivudine uses

Lamivudine is used in the treatment of chronic hepatitis B virus (HBV) infection.

How lamivudine works

Lamivudine is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

Common side effects of lamivudine

Headache, Fever, Cough, Fatigue, Joint pain, Low blood platelets, Pancreatic inflammation, Insomnia (difficulty in sleeping), Peripheral neuropathy (tingling and numbness of feet and hand), Decreased white blood cell count (neutrophils), Gastrointestinal disturbance, Rash, Hair loss, Muscle disorders, General discomfort, Anemia (low number of red blood cells), Increased liver enzymes, Lactic acidosis, Rhabdomyolysis, Pure red cell aplasia, Hepatitis (viral infection of liver), Elevated levels of serum amylase, Angioedema (swelling of deeper layers of skin)

Available Medicine for Lamivudine

  • ₹99 to ₹205
    Cipla Ltd
    4 variant(s)
  • ₹80 to ₹91
    Hetero Drugs Ltd
    3 variant(s)
  • ₹670
    Emcure Pharmaceuticals Ltd
    1 variant(s)
  • ₹1350
    Glaxo SmithKline Pharmaceuticals Ltd
    1 variant(s)
  • ₹538
    Macleods Pharmaceuticals Pvt Ltd
    1 variant(s)
  • ₹91
    Alkem Laboratories Ltd
    1 variant(s)
  • ₹81
    Taj Pharma India Ltd
    1 variant(s)
  • ₹99
    Shantha Biotech
    1 variant(s)
  • ₹103 to ₹117
    Sain Medicaments Pvt Ltd
    2 variant(s)
  • ₹76 to ₹101
    Sun Pharmaceutical Industries Ltd
    2 variant(s)

Expert advice for Lamivudine

  • You have been prescribed Lamivudine for the treatment of chronic hepatitis B virus (HBV) infection.
  • In combination with other medicines, it is used for the treatment of HIV infections.
  • Take it with food, as this increases the absorption of the medicine into the body.
  • Lamivudine may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • You may still develop infections or other illnesses associated with viral infection while taking this medication.
  • You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them.
  • During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepatitis B virus and blood cells in your blood.

Frequently asked questions for Lamivudine

Lamivudine

Q. How should I take Lamivudine?
Lamivudine should be taken in the dose and duration advised by the doctor. This medicine can be taken with or without food. However, it is better to take it at a fixed time of the day to avoid the chances of missing a dose.
Q. Is Lamivudine effective?
Lamivudine is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Lamivudine too early, the symptoms may return or worsen.
Q. What is drug resistance? Can I develop drug resistance with Lamivudine?
Drug resistance is a state where the medicine which was once effective in treating an infection becomes ineffective. This mainly happens due to the ability acquired by the virus or bacteria to get modified inside the body which affects the overall working of the medicine. Hence, the medicine is no longer able to fight against the virus or bacteria. Generally, drug resistance with Lamivudine is more likely to happen if you take less dose than what is recommended.
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Q. How long should I take Lamivudine?
Do not stop taking entecavir without consulting your doctor. Stopping entecavir before treatment may worsen your hepatitis. This can happen during the first several months after you stop taking entecavir. Take the medicine strictly as advised and do not miss any dose.
Q. What if I forget to take a dose of Lamivudine?
If you forget a dose of Lamivudine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Q. What if HIV infection co-exists with HBV infection? Will this affect treatment with Lamivudine?
In HBV patients who are diagnosed with HIV, Lamivudine is not recommended until and unless these patients start taking medicines for HIV management. Starting Lamivudine in such patients may cause resistance to the prescribed HIV medicines. Therefore, doctors recommend tests for HIV in patients diagnosed with HBV infection before starting treatment with Lamivudine.
Q. Can Lamivudine cure hepatitis B?
No, Lamivudine does not cure hepatitis B but may improve the condition of the liver. It may decrease the amount of hepatitis B virus (HBV) present in the body. This is done by limiting the ability of HBV to multiply and further infect new liver cells.
Q. Is Lamivudine safe?
Lamivudine is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Content on this page was last updated on 17 June, 2020, by Dr. Varun Gupta (MD Pharmacology)