Hydroxyurea
Information about Hydroxyurea
Hydroxyurea uses
Hydroxyurea is used in the treatment of sickle cell anemia and head and neck cancer.
How hydroxyurea works
In cancer, Hydroxyurea works by blocking an enzyme (ribonucleotide reductase) which is required for synthesis of DNA. This prevents the cancer cells from growing and multiplying. In sickle cell disease, it works by increasing fetal haemoglobin (HbF) levels in red blood cells (RBCs). This helps the RBCs assume a normal shape, improves blood flow and protects against complications such as painful sickle cell episodes.
Common side effects of hydroxyurea
Azoospermia (absence of sperms), Decreased appetite, Fever, Oligospermia (low sperm count), Skin cancer, Bone marrow suppression, Hallucination, Convulsion, Peripheral neuropathy (tingling and numbness of feet and hand), Pulmonary fibrosis, Pulmonary edema, Pancreatic inflammation, Liver toxicity, Cutaneous vasculitis, Increased uric acid level in blood
Available Medicine for Hydroxyurea
Expert advice for Hydroxyurea
- Take it at the same time every day, either with or without food.
- It is advisable to stay hydrated and drink plenty of fluids while taking Hydroxyurea.
- Do not skip any dose and complete the course as suggested by your doctor.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- Your doctor may get regular blood tests done to monitor your electrolyte levels, liver function, blood cell count in your blood.
Frequently asked questions for Hydroxyurea
Hydroxyurea
Q. How to get relief from diarrhea while on treatment with Hydroxyurea?
Food items with soluble fiber can help relieve diarrhea as they help absorb excess fluid from the body. These food items include bananas (ripe), oranges, boiled potatoes, white rice, curd, and oatmeal. Diarrhea can cause dehydration in the body, so drink 8-10 glasses of water to avoid dehydration. You can also have soups and juice frequently to hydrate yourself.
Q. Should I avoid any food and drinks while taking Hydroxyurea?
You can continue with your normal diet unless your doctor tells you otherwise. However, it is advisable to sip water regularly to prevent you from becoming dehydrated, eat small, simple but nourishing snacks every few hours rather than large meals, and suck on hard candy or popsicles to prevent nausea and vomiting.
Q. How to cope with tiredness and weakness after starting treatment?
Various things can help you to reduce tiredness and cope with it, for example, gentle exercise. Always consult your doctor before doing any kind of exercise.