Amphotericin B
Information about Amphotericin B
Amphotericin b uses
Amphotericin B is used in the treatment of severe fungal infections and kala-azar.
How amphotericin b works
Amphotericin B is an antifungal medication. It kills fungi by destroying the fungal cell membrane.
Common side effects of amphotericin b
Nausea, Vomiting, Chills, Headache, Anemia (low number of red blood cells), Decreased potassium level in blood, Abdominal pain, Blurred vision, Low blood platelets, Arrhythmia (irregular heartbeats), Abnormal liver function tests, Decreased magnesium level in blood, Itching, Diarrhea, Decreased appetite, Hypotension (low blood pressure), Skin rash, Nephrocalcinosis, Increased creatinine level in blood, Abnormal renal function tests, Agranulocytosis (deficiency of granulocytes in the blood), Decreased white blood cell count (lymphocytes), Peripheral neuropathy (tingling and numbness of feet and hand), Bronchospasm, Muscle pain, Acute renal failure, Maculopapular rash, Skin exfoliation, Toxic epidermal necrolysis, Stevens-Johnson syndrome, Weight loss, Joint pain, Cardiac arrest, Deafness, Renal tubular acidosis, Jaundice, Coagulation disorder, Increased white blood cell count (eosinophils), High white blood cell count, Vertigo, Anuria
Available Medicine for Amphotericin B
Expert advice for Amphotericin B
- It is usually given as an injection over 1-2 hours under the supervision of a medical professional.
- Amphotericin B can cause rash, chills, headache, and tiredness during initial days of the treatment, but these may fade away with time.
- Your doctor may ask you for regular blood tests to monitor your blood sugar, potassium, magnesium and kidney function.
- Inform your doctor immediately if you notice pain or blood upon urination, swelling of the face and trouble breathing.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Frequently asked questions for Amphotericin B
Amphotericin B
Q. Is Amphotericin B fungistatic or fungicidal?
Amphotericin B is fungicidal in nature, it acts by killing the fungus
Q. Is Amphotericin B light sensitive?
Amphotericin B is not light sensitive
Q. What is Amphotericin B liposomal?
Liposomal Amphotericin B is a lipid-associated formulation. Liposomal encapsulation or incorporation into a lipid complex of Amphotericin B can substantially improves drug safety especially nephrotoxicity associated with the drug