Rs.123for 1 strip(s) (10 tablets each)
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Composition FOR Tryptobal

Amitriptyline(10mg),Methylcobalamin(1500mcg)

food interaction for Tryptobal

alcohol interaction for Tryptobal

pregnancy interaction for Tryptobal

lactation interaction for Tryptobal

food
alcohol
pregnancy
lactation
Tryptobal Tablet may be taken with or without food, but it is better to take it at a fixed time.
None
CAUTION
It is unsafe to consume alcohol with Tryptobal Tablet.
UNSAFE
Tryptobal Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Tryptobal Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Tryptobal

Amitriptyline(10mg)

Uses

Amitriptyline is used in the treatment of depression, neuropathic pain and migraine.

How it works

Amitriptyline contains Amitriptyline, a tricyclic antidepressant. It has anticholinergic and sedative properties. It prevents the reuptake, and hence the inactivation of neurotransmitters called noradrenaline and serotonin, that are present at the nerve terminals in our brain. Reuptake prevention of these monoamine neurotransmitters potentiate their action in the brain. This appears to be associated with the antidepressant activity and helps in regulating the mood. It also stops the transmission of pain signals from nerves to the brain thereby relieving neuropathic pain (pain from damaged nerves).

Common side effects

Constipation, Dryness in mouth, Orthostatic hypotension (sudden lowering of blood pressure on standing), Weight gain, Aggressive behavior, Nasal congestion (stuffy nose), Sleepiness, Dizziness, Headache, Decreased libido, Nausea, Fatigue, Confusion, Tremors, Speech disorder, Palpitations, Taste change, Paresthesia (tingling or pricking sensation), Abnormality of voluntary movements, Loss of accommodation, Atrioventricular block, Micturition disorders, Erectile dysfunction, Abnormal ECG, Decreased sodium level in blood, Facial swelling, Hypomania, Mania, Anxiety, Insomnia (difficulty in sleeping), Convulsion, Ringing in ear, Rash, Liver impairment, Akathisia (inability to stay still), Suicidal thoughts, Arrhythmia (irregular heartbeats), Hair loss
Methylcobalamin(1500mcg)

Uses

Methylcobalamin is used in vitamin B12 deficiency.

How it works

Methylcobalamin is a form of vitamin B12 that restores its level in the body thereby helping in treating certain anemias and nerve problems.

Common side effects

Decreased appetite, Diarrhea, Nausea, Rash

SUBSTITUTES FOR Tryptobal

10 Substitutes
10 Substitutes
Sorted By
RelevancePrice
  • Amicobal 10mg/1500mcg Tablet
    (10 tablets in strip)
    Ergos Life Sciences
    Rs. 16/Tablet
    Tablet
    Rs. 165
    pay 30% more per Tablet
  • Joycobal AT 10mg/1500mcg Tablet
    (10 tablets in strip)
    Zenfo Med Remedies Private Limited
    Rs. 14.10/Tablet
    Tablet
    Rs. 145
    pay 15% more per Tablet
  • Amicobal Tablet
    (15 tablets in strip)
    Ergos Life Sciences
    Rs. 17.13/Tablet
    Tablet
    Rs. 259.90
    pay 39% more per Tablet
  • Amitias M 10 Tablet
    (10 tablets in strip)
    Matias Healthcare Pvt Ltd
    Rs. 13.50/Tablet
    Tablet
    Rs. 139
    pay 10% more per Tablet
  • Triptorain-MC 10 Tablet
    (10 tablets in strip)
    Wallnutree Neurosciences India Pvt Ltd
    Rs. 13.60/Tablet
    Tablet
    Rs. 140
    pay 11% more per Tablet

Expert advice FOR Tryptobal

  • It may take 4 to 6 weeks for Amitriptyline to start working. Keep taking it as prescribed.
  • It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Amitriptyline as it may cause excessive sleepiness.
  • Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
  • It may cause sudden drop in your blood pressure. Rise slowly if you have been sitting or lying down.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts, or feelings. This is very important when an antidepressant medicine is started or when the dose is changed.

Frequently asked questions FOR Tryptobal

Amitriptyline

Q. What other lifestyle changes should I make to get maximum benefit of Amitriptyline?
Antidepressants, including Amitriptyline, are just one of several approaches to treat depression. Certain lifestyle changes can help you get maximum benefit of Amitriptyline and help you recover fast. Keeping active and eating a healthy diet can make a significant difference to how quickly you recover from depression. Think positively and try to discuss your thoughts with others to reduce stress. Practice yoga or take up a hobby. Ensure that you have a sound sleep to calm your mind. Stay away from smoking or alcohol consumption as these will only worsen your depression. Take your medicines as prescribed even if you start feeling better.
Q. I have been prescribed Amitriptyline for pain. When will I start feeling better?
You may start feeling better after 2 weeks of starting Amitriptyline. However, it may take 4-6 weeks to see the full benefits of the medicine.
Q. Can I stop taking Amitriptyline when my pain is relieved?
No, do not stop taking Amitriptyline even if the pain is relieved. You should use Amitriptyline as advised by the doctor. Stopping the medicine suddenly may cause unpleasant symptoms like headache, feeling unwell, sleeplessness and irritability. Consult your doctor for the duration of the treatment since the dose of Amitriptyline needs to be reduced gradually.
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Q. Is there anything I need to be careful about while on therapy with Amitriptyline?
Amitriptyline may cause drowsiness and dizziness, especially in the beginning of the treatment. So, avoid driving or using machinery until you know how the medicine affects you. Also, it is not advisable to drink alcohol during treatment with this medicine as it might increase sleepiness.
Q. Can the use of Amitriptyline affect my sex life?
Yes, Amitriptyline can affect sex life in both men and women. It may cause decreased sexual desire or you may experience discomfort during intercourse. Men may experience inability to develop or maintain an erection during sexual activity and may be unable to have an orgasm. If you notice these symptoms, do not stop taking the medicine but consult your doctor.
Q. I have been taking Amitriptyline for depression since a week and recently I have been wanting to harm myself. What should I do? Is it because of the medicine?
You should immediately consult your doctor or go to the hospital. Your suicidal tendencies may have increased because of your disease or the medicine. Generally, Amitriptyline takes about 2 weeks to show its effect but may take longer. Therefore, when you start taking Amitriptyline, you may have thoughts about killing or harming yourself. This is more common in people who previously had suicidal tendencies or are young adults (less than 25 years old). However, the effect of medicine is different for every individual.
Q. Can Amitriptyline cause urinary problems?
Yes, Amitriptyline can cause urinary problems. It is more commonly seen in elderly patients who are more than 65 years old. The patient may face difficulty in passing urine which can further lead to a urinary tract infection. Consult your doctor immediately if you develop these symptoms.
Q. If my pain is not relieved, can I take more than the recommended dose?
No, you should use Amitriptyline strictly as prescribed by the doctor. If the dose exceeds, you may develop drowsiness, confusion, difficulty in speech, dry mouth, tiredness, difficulty in walking, fever, difficulty in breathing, blue discoloration of the skin and decreased heartbeat. Your pain may not be relieved because Amitriptyline takes about 2 weeks to show its effect, but it may take longer in some cases. The duration of treatment can differ from individual to individual. Consult your doctor if your symptoms are not relieved.
Q. Does Amitriptyline cause any effect on pregnancy or the newborn?
Do not take Amitriptyline during pregnancy unless recommended by the doctor. If you take this medicine during the last trimester of the pregnancy, the newborn may develop symptoms such as irritability, rigidity, irregular body movements, irregular breathing, poor drinking, loud crying, difficulty in urinating and constipation.
Q. How long does Amitriptyline take to work?
You may see an improvement in your symptoms after a couple of weeks, although it usually takes between 4 and 6 weeks before you feel the benefits. Do not stop taking Amitriptyline after 1 or 2 weeks just because you feel it is not helping your symptoms. Give the medicine at least 6 weeks to work.
Q. How will Amitriptyline make me feel?
Antidepressants like Amitriptyline help to gradually lift your mood. You may notice that you sleep better and are less anxious. You may worry less about little things that used to bother you. Amitriptyline will not make you feel excessively or unusually happy. It will help you feel like yourself again.

Methylcobalamin

Q. What is Methylcobalamin?
Methylcobalamin contains vitamin B12. Vitamin B12 is an essential nutrient which is required by the body to make red blood cells and maintain a healthy nervous system. It is also important for releasing energy from food and using vitamin B11 (folic acid).
Q. Why can’t I get sufficient vitamin B12 from my diet?
You can get vitamin B12 from sources like meat, fish, eggs and dairy products. While people who are vegetarian or vegan may not get Vitamin B12 as it is not found naturally in foods such as fruits, vegetables and grains. Therefore, deficiency of Vitamin B12 is usually noticed in vegetarians or vegans.
Q. What happens if I have vitamin B12 deficiency?
Deficiency of vitamin B12 may cause tiredness, weakness, constipation, loss of appetite, weight loss and megaloblastic anemia (a condition when red blood cells become larger in size than normal). It may also lead to nerve problems such as numbness and tingling in the hands and feet. Other symptoms of vitamin B12 deficiency may include problems with balance, depression, confusion, dementia, poor memory and soreness of the mouth or tongue.
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Q. How should Methylcobalamin be taken?
Methylcobalamin should be taken in the dose and duration advised by your doctor. It can be taken with or without food. However, it would be best to take it at the same time each day to avoid the chances of missing a dose.
Q. What if I forget to take a dose of Methylcobalamin?
If you forget a dose of Methylcobalamin, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Q. Is Methylcobalamin safe?
Methylcobalamin is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Content on this page was last updated on 29 November, 2023, by Dr. Varun Gupta (MD Pharmacology)