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Tri Zyromet G 2mg Tablet

Aagam Life Sciences Pvt Ltd
Tablet
As per Ministry of Health and Family Welfare
BANNED FOR SALE
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Composition FOR Tri Zyromet G

Glimepiride(2mg),Metformin(500mg),Pioglitazone(7.5mg)

food interaction for Tri Zyromet G

alcohol interaction for Tri Zyromet G

pregnancy interaction for Tri Zyromet G

lactation interaction for Tri Zyromet G

food
alcohol
pregnancy
lactation
Tri Zyromet G 2mg Tablet is to be taken with food.
Tri Zyromet G 2mg Tablet may cause stomach upset if taken empty stomach.
None
CAUTION
It is unsafe to consume alcohol with Tri Zyromet G 2mg Tablet.
UNSAFE
Tri Zyromet G 2mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Tri Zyromet G 2mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Tri Zyromet G

Glimepiride(2mg)

Uses

Glimepiride is used in the treatment of type 2 diabetes mellitus. It is used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

How it works

Glimepiride is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.

Common side effects

Hypoglycemia (low blood glucose level), Headache, Nausea, Dizziness, Diarrhea, Vasculitis, Hypersensitivity, Vomiting, Abdominal pain, Abnormal liver function tests, Blood cell abnormalities, Hemolytic anemia, Decreased blood cells (red cells, white cells, and platelets)
Metformin(500mg)

Uses

 
Metformin is an antidiabetic medicine that helps to control blood sugar in people with type 2 diabetes mellitus.
.

How it works

Metformin is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from the intestines, and increasing the body's sensitivity to insulin.

Common side effects

Nausea, Vomiting, Diarrhea, Headache, Flatulence, Indigestion, Hypoglycemia (low blood glucose level), Vitamin B12 deficiency, Abdominal discomfort, Lactic acidosis, Hepatitis (viral infection of liver), Drug eruptions
Pioglitazone(7.5mg)

Uses

It is used in combination with diet and exercise to lower blood glucose in adults with type 2 diabetes mellitus.
. It is used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

How it works

Pioglitazone is an anti-diabetic medication. It works by increasing the body's sensitivity to insulin, a natural substance that helps control blood sugar levels.

Common side effects

Bone fracture, Headache, Sinus inflammation, Bladder cancer, Muscle pain, Upper respiratory tract infection, Bronchitis (inflammation of the airways), Anemia (low number of red blood cells), Hypoglycemia (low blood glucose level), Edema (swelling), Heart failure, Visual disturbance, Increased alanine aminotransferase, Rhabdomyolysis

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Expert advice FOR Tri Zyromet G

  • Exercise regularly, eat a healthy diet and take your other diabetes medicines (if prescribed) alongside.
  • Be careful while driving or operating machinery until you know how Glimepiride affects you.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
  • Monitor your blood sugar level regularly while you are taking Glimepiride.

Frequently asked questions FOR Tri Zyromet G

Glimepiride

Q. What is the dosage of Glimepiride?
The recommended starting dose of Glimepiride is 1 mg or 2 mg once daily, administered with breakfast. If you are at a higher risk of low blood sugar (e.g., the elderly or patients with renal impairment), you will be given a starting dose of 1 mg once daily. The usual maintenance dose is 1–4 mg once daily. The maximum recommended dose is 8 mg once daily. After reaching a daily dose of 2 mg, the dosage will be increased not more than 2 mg at 1- to 2-week intervals, based on your blood glucose level.
Q. Can you take Glimepiride on an empty stomach?
No. Taking Glimepiride on an empty stomach can cause your blood sugar levels to become too low. Low blood sugar can cause dizziness, shaking, anxiety, irritability, a fast heartbeat, and confusion. Therefore, you should always take the medicine with breakfast or the first meal of the day. If you are skipping your meal, then you should also avoid taking Glimepiride.
Q. Can Glimepiride cause dizziness?
Yes, Glimepiride can cause dizziness as a side effect. If this happens to you, sit or lie down until the symptoms pass. Always carry some sugary food or fruit juice with you in case you experience dizziness while travelling.
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Q. Does Glimepiride make you sleepy?
Glimepiride itself does not cause sleepiness. However, it may cause hypoglycemia (low blood sugar) when used with other anti-diabetes medicine. Because of this you may feel sleepy or have problems in sleeping.
Q. Can Glimepiride cause weight gain?
Yes, Glimepiride can cause weight gain. Glimepiride is a sulfonylurea drug and causes the pancreas to release insulin. It may stimulate hunger and cause mild weight gain in some people. Patients are advised to eat a healthy balanced diet and exercise regularly to keep their weight stable.
Q. What should you not eat while taking Glimepiride?
It is advisable to avoid foods that are high in saturated and trans fats, instead consume fats from fish and nuts. Control your carbohydrate intake as this directly affects your blood sugar.
Q. Who should not take Glimepiride?
Glimepiride should be avoided by patients who are allergic to it, have severe kidney or liver disease, have G6PD-deficiency (an inherited condition affecting red blood cells) or are due to have surgery. Additionally, patients who are trying to get pregnant, are pregnant or breastfeeding, or have insulin-dependent diabetes (type 1 diabetes mellitus) should avoid taking Glimepiride.
Q. Is Glimepiride safe for kidneys?
Glimepiride does not affect kidneys in patients with normal kidney function. However, its use should be avoided in patients with severe kidney disease since Glimepiride is principally eliminated by the kidneys.
Q. Does Glimepiride cause memory loss?
No, it is not known that Glimepiride causes memory loss. However, the use of Glimepiride may cause low blood sugar which may cause problems with concentration and reduced alertness.
Q. How long does it take for Glimepiride to start working?
Glimepiride takes about 2 to 3 hours to reduce blood sugar levels. You may not feel any difference, but this does not mean the medicine is not working. Continue taking the medication as directed by your doctor and if you have any concerns, discuss it with your doctor.
Q. How long do I need to take Glimepiride? Can I stop the medication?
Usually, the treatment for diabetes is suggested for a long term. You may have to continue the treatment life long. Glimepiride only controls the sugar levels but does not cure it. Do not stop taking Glimepiride without talking to your doctor. If you stop taking Glimepiride suddenly your diabetes may get worse.
Q. What can happen if I take more than the recommended dose of Glimepiride?
Glimepiride should be taken strictly as advised by the doctor. Overdose of Glimepiride may significantly decrease your blood sugar levels (hypoglycemia). If you think you have taken an excess dose and experience a dip in your sugar level, consume enough sugar (e.g., a small bar of sugar cubes, sweet juice or sweetened tea) and inform a doctor immediately. Severe cases of hypoglycemia accompanied by loss of consciousness and coma require immediate medical treatment and admission into hospital.
Q. Is Glimepiride safe to use?
Yes, Glimepiride tablet is safe when used as directed by the doctor. However, it may show some side effects. For best results, it should be used in the correct dose and at the same time each day.
Q. Can people with diabetes have proteins?
Yes, people with diabetes must include proteins along with other essential nutrients in their daily diet. Proteins are one of the major energy providers among all essential nutrients. Besides, being the building blocks of the human body, proteins break down into glucose to release energy. Unlike carbohydrates, the metabolism of proteins into glucose is much slower. Therefore, the release of energy usually takes a few hours after consumption. Thus, the spike in blood sugar levels might occur after a few hours when you are on a high-protein diet.
Q. Are artificial sweeteners good for people with diabetes?
No, artificial sweeteners are not good for people with diabetes. They are composed of chemicals that can cause mild to severe side effects. Thus, it is better to limit or avoid their use as much as you can.
Q. Can diabetes cause kidney failure?
Yes, uncontrolled diabetes can cause kidney failure. In the long run, diabetes can affect the kidneys leading to a condition called diabetic nephropathy. Diabetic nephropathy is a condition that is a major cause of kidney failure in patients with diabetes. The best way to prevent damage to kidneys is by keeping diabetes in check, making dietary changes, monitoring sugar levels regularly, getting routine blood tests done, and taking prescribed medications on time.
Q. Can diabetes be cured?
Diabetes is a condition that causes changes in your blood glucose levels, which if left uncontrolled, can lead to serious health complications affecting the heart, brain, kidneys, and eyes. However, with simple lifestyle changes, diet, and medications, one can manage their condition and lead a healthy life.

Metformin

Q. What does Metformin do exactly?
People with type 2 diabetes are not able to make enough insulin or respond normally to the insulin made by their bodies. When this happens, the concentration of sugar/glucose increases in the blood. Metformin acts in several ways to reduce the increased levels of sugar in blood. Metformin decreases glucose production from the liver and decreases absorption of glucose from the intestine after taking food while improving the sensitivity of the body organs and muscles towards insulin. This helps improve the uptake of glucose from the blood. It also helps your body to respond better to the insulin it makes naturally.
Q. Does Metformin cause weight loss?
Yes, Metformin has been shown to cause weight loss in people who are overweight or obese. It may also cause a modest loss in weight in those overweight and obese individuals who are at risk for diabetes. In addition, patients who are sensitive or resistant to insulin may also show weight loss. But, do not start taking this medicine for weight loss on your own. Consult your doctor for the same.
Q. What are the benefits of taking Metformin?
Metformin is one of the first medicines that is given to patients with high blood sugar levels. It helps control blood sugar levels. It promotes the body’s response to the insulin made by the pancreas, decreases the amount of sugar made by the liver and decreases the amount of sugar absorbed by the intestines. Unlike other oral antidiabetic medicines, Metformin when taken alone, rarely causes low blood sugar as it prevents the pancreas from secreting more insulin. In addition to being a great medicine to lower blood sugar levels, it also helps in controlling weight gain.
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Q. Can Metformin make you sleepy?
Metformin usually does not cause sleepiness and is well tolerated. However, the use of Metformin may rarely cause sleep disorders and insomnia. Sleepiness may be due to a very serious side effect called lactic acidosis, which particularly occurs if your kidneys are not working properly. Contact your doctor if you feel sleepy or tired while taking Metformin.
Q. How to take Metformin?
Take Metformin with or after a meal. Do not crush or chew the tablets and swallow it with a glass of water. If your doctor has prescribed one tablet a day, prefer taking it in the morning with breakfast. If you have been prescribed two tablets a day, then take one in the morning and other in the evening with dinner. In case of three doses a day, apart from morning and evening, you can take it with lunch. Taking Metformin with meals will reduce its digestive problems like indigestion, nausea, vomiting, diarrhea, stomach ache and loss of appetite.

Pioglitazone

Q. Can Pioglitazone cause weight gain?
Pioglitazone commonly causes weight gain which may be dose-related. The reason for this weight gain could be fat accumulation. However, in heart failure patients it could be due to water retention in the body. Therefore, it is important to monitor weight in heart failure cases.
Q. Can Pioglitazone cause heart failure?
Pioglitazone can cause fluid retention which may aggravate or speed up heart failure. The doctor usually starts with the lowest available dose and increases the dose gradually while treating patients who have at least one risk factor for heart failure (previous heart attack, coronary artery disease, elderly). Heart failure is more common when Pioglitazone is used with insulin.
Q. Can you take Pioglitazone and metformin together?
Yes, Pioglitazone can be used with metformin where sufficient blood sugar management was not possible with metformin alone. This combination of medicines can be used in adult patients with type 2 diabetes mellitus and overweight patients with poor blood sugar control.
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Q. What time of day should you take Pioglitazone?
It is usually prescribed once daily and can be taken at any time of the day but preferably at the same time each day. It can be taken with or without food. You should take Pioglitazone exactly as prescribed by your doctor.
Q. How long do I need to take Pioglitazone? Can I stop the medicine for some time?
Continue taking Pioglitazone as long as your doctor recommends taking it. Treatment for diabetes mellitus is long-term so you may have to take it lifelong. However, if you have to stop it then consult with your doctor who will suggest an alternative. Do not stop taking it without consulting your doctor as it may cause blood sugar levels to rise, which could be harmful to you.
Q. Can Pioglitazone cause bladder cancer?
Pioglitazone may increase the risk of bladder cancer, though it is very rare. Immediately consult your doctor if you experience blood in your urine, pain when urinating or a sudden need to urinate, during treatment with this medicine. Pioglitazone should not be used in patients with a prior history of bladder cancer or having bladder cancer.
Q. Does Pioglitazone affect liver?
Yes, Pioglitazone may cause an increase in liver enzymes, and treatment with Pioglitazone should be stopped if liver enzymes increase. Hence, levels of liver enzymes should be periodically checked while on treatment with this medicine. Pioglitazone should not be prescribed to patients with liver disease.
Q. What kind of medicine is Pioglitazone? Is it like metformin?
Pioglitazone belongs to the thiazolidinediones class of anti-diabetic medicines. It helps control blood sugar levels by improving how your body uses a hormone called insulin. This is done by helping your cells become more sensitive to the insulin your body makes.

Content on this page was last updated on 09 April, 2024, by Dr. Varun Gupta (MD Pharmacology)