Terbilan-Plus Cream

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Rs.124for 1 tube(s) (15 gm Cream each)
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Composition FOR Terbilan-Plus

Itraconazole(1% w/w),Terbinafine(1% w/w)

food interaction for Terbilan-Plus

alcohol interaction for Terbilan-Plus

pregnancy interaction for Terbilan-Plus

lactation interaction for Terbilan-Plus

medicine interaction for Terbilan-Plus

food
alcohol
pregnancy
lactation
medicine
No interaction found/established
No interaction found/established
Information regarding the use of Terbilan-Plus Cream during pregnancy is not available. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Terbilan-Plus Cream during breastfeeding is not available. Please consult your doctor.
CONSULT YOUR DOCTOR
No interaction found/established

SALT INFORMATION FOR Terbilan-Plus

Itraconazole(1% w/w)

Uses

Itraconazole is used in the treatment of fungal infections. It is used to treat fungal infections of the mouth or vagina (thrush), skin and other parts of the body such as finger and toenails.

How it works

Itraconazole is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane, thereby treating your skin infection.

Common side effects

Nausea, Menstrual disorder, Increased triglyceride level in blood, Diarrhea, Abdominal pain, Constipation, Flatulence, Headache, Taste change, Vomiting, Sinus inflammation, Upper respiratory tract infection, Inflammation of the nose, Hypersensitivity, Dyspepsia, Abnormal liver function, Urticaria, Decreased white blood cell count (lymphocytes), Serum sickness, Angioneurotic edema, Paresthesia (tingling or pricking sensation), Visual disturbance, Hearing loss, Heart failure, Pancreatic inflammation, Liver toxicity, Toxic epidermal necrolysis, Stevens-Johnson syndrome, Acute generalized exanthematous pustulosis, Erythema multiforme, Frequent urge to urinate, Erectile dysfunction, Edema (swelling), Increased creatine phosphokinase (CPK) level in blood
Terbinafine(1% w/w)

Uses

Terbinafine is used in the treatment of fungal infections.

How it works

Terbinafine is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane, thereby treating your skin infection.

Common side effects

Headache, Diarrhea, Rash, Itching, Taste change, Nausea, Abdominal pain, Decreased appetite, Decreased white blood cell count (neutrophils), Erythema (skin redness), Increased liver enzymes, Joint pain, Muscle pain, Urticaria, Dyspepsia, Skin exfoliation, Weight loss, Skin lesion, Scab, Skin disorder, Pigmentation disorders, Burning sensation, Application site pain, Liver failure, Agranulocytosis (deficiency of granulocytes in the blood), Low blood platelets, Severe skin reactions, Eye irritation, Dry skin, Contact dermatitis

SUBSTITUTES FOR Terbilan-Plus

13 Substitutes
13 Substitutes
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  • Itromed TF Cream
    (15 gm Cream in tube)
    Leeford Healthcare Ltd
    Rs. 5.27/gm of Cream
    generic_icon
    Rs. 110
    save 36% more per gm of Cream
  • Fungizee-T Cream
    (15 gm Cream in tube)
    Zeelab Pharmacy Pvt Ltd
    Rs. 2.40/gm of Cream
    generic_icon
    Rs. 40
    save 71% more per gm of Cream
  • Itzo TF Cream
    (15 gm Cream in tube)
    R.T. Pharma
    Rs. 9.27/gm of Cream
    generic_icon
    Rs. 143
    pay 12% more per gm of Cream
  • Itroflex Cream
    (15 gm Cream in tube)
    Carlton Dermatology
    Rs. 10.80/gm of Cream
    generic_icon
    Rs. 167
    pay 31% more per gm of Cream
  • Itralon T Cream
    (15 gm Cream in tube)
    Rs. 7.73/gm of Cream
    generic_icon
    Rs. 120
    save 6% more per gm of Cream

Expert advice FOR Terbilan-Plus

  • Itraconazole helps treat fungal infections of mouth, skin, vagina or any other parts of the body.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • Take it with food, preferably at the same time everyday.
  • Use a reliable method of contraception to prevent pregnancy while taking this medicine.
  • Do not take indigestion remedies (antacids) within two hours of taking Itraconazole.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Inform your doctor if you develop allergic reactions, nerve pain, or hearing loss.

Frequently asked questions FOR Terbilan-Plus

Itraconazole

Q. What is Itraconazole used for?
Itraconazole is used to treat fungal infections caused by Trichophyton spp., Microsporum spp., and Epidermophyton floccosum. The infections caused could be ringworm infection, infection of feet, or infection in groin and buttocks. This medicine also treats persistent infection of fingernails and toenails, persistent candida (yeast) infections of vagina or candida (yeast) infections of the mouth or throat in patients with lower resistance to disease. It is also used in the treatment of cryptococcal infection and infections caused by histoplasma, aspergillus and blastomyces.
Q. For how long do I need to take Itraconazole?
The dose and length of treatment will depend on the type and site of infection and your response to the treatment. For example, if you are taking Itraconazole for athlete’s foot (fungal infection of the skin on the feet and between the toes), the dose may need to be taken for 30 days. While, on the other hand, if you are taking it for candidal infection of vagina, the dose may take about 1 to 3 3 days depending on the dosage advised by the doctor.
Q. What should I do if I skip a dose of Itraconazole?
If you forget to take your dose, take the missed dose as soon as you remember. However, if it is time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the forgotten dose.
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Q. I am taking Itraconazole for nail infection but there does not seem to be any improvement. Can I stop taking it?
No, you should not stop taking Itraconazole without completing the entire course. This is because if you stop the medication then your fungal infection may not get completely cured. It usually takes about 6-9 months for the nail lesions to get cured and after that the new nail also takes several months to grow. Therefore, do not worry if you do not see any improvement during the treatment.
Q. Why has my doctor asked me to get blood tests done?
Your doctor may have prescribed blood tests to monitor your liver’s functioning. This is because the use of Itraconazole may cause serious liver damage. Therefore, if you develop loss of appetite, nausea, vomiting, dark urine or abdominal pain while taking Itraconazole, immediately inform your doctor.
Q. Can I take an antacid and Itraconazole together?
Itraconazole can be utilized by the body if there is sufficient acid in the stomach. Medicines for stomach ulcers, heartburn or indigestion neutralize the acid produced by the stomach. Therefore, it is advised to avoid taking antacids or any such medicine for a minimum of 2 hours after taking Itraconazole. However, if you are taking antacids (medicines that stop the production of stomach acid), take Itraconazole capsules with a drink of cola.
Q. What is drug resistance? Is it possible to develop resistance to Itraconazole?
Drug resistance is a condition when the fungi get modified in your body and the medicine is not able to work. There are reports which suggest resistance of some candida species (krusei, glabrata and tropicalis) with Itraconazole. Itraconazole should not be used for infection caused due to these species. It is advised to take the complete course of Itraconazole to avoid drug resistance.
Q. I am on alprazolam for quite some time. Is it okay if I start Itraconazole now?
Yes, you can take both Alprazolam and Itraconazole together, but keep a watch on the side effects of Alprazolam such as lightheadedness or drowsiness. If you experience side effects after taking Itraconazole, talk to your doctor who will modify the dose of alprazolam.
Q. My doctor prescribed Itraconazole to me but not to my friend who had a similar fungal infection because she was on dofetilide. Why is it so?
Your doctor did not prescribe Itraconazole to your friend because Itraconazole interferes with the working of dofetilide. This interference can cause disturbed electrical activity of the heart, which can be harmful for the patient.

Terbinafine

Q. Can Terbinafine be safe for use in patients with liver cirrhosis?
Oral intake of Terbinafine is not recommended in patients with chronic or active liver disease. Your doctor may prescribe a liver function test to check whether the liver is functioning effectively or not. This is done because the medicine gets metabolized by liver enzymes and any inefficiency in liver function can lead to increased levels of the medication in the blood, resulting in increased side effects and toxicity. Therefore, it is important to inform your doctor if you have any liver disease or cirrhosis. Also, inform your doctor about the medicines you may be taking as taking Terbinafine with another medicine can lead to liver toxicity and Terbinafine by acting on the liver enzymes can change the levels of other drugs. Your doctor may suggest periodic monitoring (after 4-6 weeks of treatment) of liver function test and make dose adjustments accordingly.
Q. Can I drink tea or coffee while taking Terbinafine?
Caffeinated drinks like tea and coffee should be taken with caution while being on treatment with Terbinafine. Terbinafine decreases the rate of metabolism of caffeine by 19% which is an important constituent of coffee, thereby increasing the levels of caffeine in the blood. This increased levels of caffeine may lead to side effects such as jitteriness, headache, increased heartbeat and restlessness.
Q. How long do I need to take Terbinafine?
The usual duration of treatment for Tinea pedis (fungal infection in the foot), Tinea corporis (ringworms) and Tinea cruris (fungal infection in the groin) is about 2 to 4 weeks. However, the duration may sometimes be extended to 6 weeks. Usually, the duration of treatment for fungal infections of nails varies from 6 to 12 weeks. For fingernail fungal infections, it may take 6 weeks whereas toenail fungal infection may take about 12 weeks to recover. However, the exact duration of the therapy is decided by the doctor depending upon the type of infection, the site of infection, and the patient’s response to the therapy.
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Q. Does Terbinafine cause any skin reactions?
Yes, sensitive individuals may develop skin reactions while using Terbinafine. However, there are rare reports of people developing serious skin/hypersensitivity reactions like Stevens-Johnson syndrome, toxic epidermal necrolysis and other severe skin reactions with Terbinafine. Therefore, do not take this medication without consulting your physician. Immediately stop the medication and inform your doctor if you develop any type of skin reaction or rashes.
Q. Is Terbinafine effective?
Terbinafine is effective as an anti fungal medicine if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop taking this medicine too early, the fungus may continue to grow and the infection may return or worsen.

Content on this page was last updated on 29 November, 2023, by Dr. Varun Gupta (MD Pharmacology)