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Simvas EZ 10mg/10mg Tablet

Tablet
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Composition FOR Simvas EZ

Simvastatin(10mg),Ezetimibe(10mg)

food interaction for Simvas EZ

alcohol interaction for Simvas EZ

pregnancy interaction for Simvas EZ

lactation interaction for Simvas EZ

food
alcohol
pregnancy
lactation
Simvas EZ 10mg/10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
None
CAUTION
It is unsafe to consume alcohol with Simvas EZ 10mg/10mg Tablet.
UNSAFE
Simvas EZ 10mg/10mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
UNSAFE
Simvas EZ 10mg/10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Simvas EZ

Simvastatin(10mg)

Uses

Simvastatin is used in the treatment of high cholesterol, prevention of heart attack and stroke and high triglycerides.

How it works

Simvastatin is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required in the body to make cholesterol. It thus lowers "bad" cholesterol (LDL) and triglycerides, raising the level of "good" cholesterol (HDL).

Common side effects

Constipation, Headache, Upper respiratory tract infection, Abdominal pain, Muscle pain, Joint pain, Nausea, Increased transaminase level in blood, Muscle damage, Rhabdomyolysis, Immune-mediated necrotizing myopathy
Ezetimibe(10mg)

Uses

Ezetimibe is used in the treatment of high cholesterol.

How it works

Ezetimibe is a cholesterol absorption inhibitors. It reduces the cholesterol absorption from the intestine and lowers the levels of total cholesterol and "bad" cholesterol (LDL) in the blood.

Common side effects

Diarrhea, Joint pain, Sinus inflammation, Dizziness, Upper respiratory tract infection, Pain in extremity, Increased gamma-glutamyltransferase, Muscle damage, Rhabdomyolysis, Gallstones, Cholecystitis

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Cholesterol - TotalTriglyceridesCholesterol - LDLCholesterol - HDL
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Expert advice FOR Simvas EZ

  • It should be taken in the evening after dinner and before sleeping.
  • It should be taken in addition to regular exercise and low-fat diet to lower levels of fat in the blood.
  • Inform your doctor if you experience fatigue, muscle weakness or muscle pain. 
  • Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of liver problems such as stomach pains, unusually dark urine or yellowing of skin or eyes.
  • Inform your doctor if you have kidney disease, liver disease or diabetes before starting treatment with this medicine. If you are diabetic, monitor your blood sugar level regularly as Simvastatin may cause an increase in your blood sugar level.
  • Do not take Simvastatin if you are pregnant, planning a pregnancy or breastfeeding.
  • Simvastatin treats high cholesterol by lowering "bad" cholesterol (LDL) and triglycerides (fats). It should be taken in addition to regular exercise and low-fat diet.
  • It also reduces the risk of heart attack and stroke.
  • In general, Simvastatin is safe. It may cause diarrhea, gas or an upset stomach. If any of these happen to you, take it with food.
  • Inform your doctor if you experience fatigue, muscle weakness or muscle pain. 
  • Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of liver problems such as stomach pains, unusually dark urine or yellowing of skin or eyes.
  • Inform your doctor if you have kidney disease, liver disease or diabetes before starting treatment with this medicine. If you are diabetic, monitor your blood sugar level regularly as Simvastatin may cause an increase in your blood sugar level.
  • Do not take Simvastatin if you are pregnant, planning a pregnancy or breastfeeding.

Frequently asked questions FOR Simvas EZ

Simvastatin

Q. What should I know about high cholesterol?
Cholesterol is a type of fat present in your blood. Total cholesterol is determined by the total amount of LDL and HDL cholesterol in the body. LDL cholesterol is called “bad” cholesterol. Bad cholesterol can build up in the wall of your blood vessels and slow or obstruct blood flow to your heart, brain, and other organs. This can cause heart disease and stroke. HDL cholesterol is called “good” cholesterol as it prevents the bad cholesterol from building up in the blood vessels. High levels of triglycerides are also harmful for you.
Q. What is Simvastatin used for? How does it work?
Simvastatin belongs to a class of medicines called statins that lower the cholesterol in the blood. It is used along with a healthy diet and exercise to reduce bad cholesterol and increase the amount of good cholesterol in the blood. It works by slowing the production of cholesterol in the liver in order to decrease the amount of cholesterol that accumulates on the walls of arteries. Improving the levels of cholesterol in the blood helps to reduce the risk of heart attack or stroke.
Q. When should I take Simvastatin?
Simvastatin is generally taken once a day preferably in the evening after dinner. Try taking this medicine at the same time every day to help remember when to take it.
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Q. For how long should I take Simvastatin?
You may need to take Simvastatin for life or for as long as directed by your doctor. The cholesterol levels will be maintained only till you are taking Simvastatin. Stopping Simvastatin without starting a different treatment may increase your cholesterol levels again. This medicine has only a few side effects and is usually considered safe if taken as directed by the doctor.
Q. What foods should be avoided when taking Simvastatin?
Simvastatin is used to decrease your blood cholesterol levels. Therefore, to seek the best results of this medicine, you should avoid foods which are high in calories like fried food and junk food. It is recommended to eat a low-fat and low-cholesterol diet. Be sure to follow all the exercise and dietary recommendations made by your doctor or dietician.
Q. Does Simvastatin make you tired?
Yes, Simvastatin can make you feel tired. This is because they reduce the energy supply to the muscles in the body. However, the exact reason behind the phenomenon is unknown and needs more research. Tiredness usually occurs after exertion. Generalized fatigue is more often seen in people with heart disease or those suffering from liver illness. Simvastatin also causes muscle damage which further worsens the tiredness and so you must consult your doctor if you feel tired while taking Simvastatin.
Q. Can I take alcohol with Simvastatin?
No, it is not advised to take alcohol with Simvastatin. This is because the risk of developing liver problems increases if you drink alcohol while taking this medicine. Moreover, there is a significant increase in the triglyceride levels if Simvastatin is taken along with alcohol. This can further lead to liver damage and also worsen some of the side effects such as muscle pain, muscle weakness and tenderness. People with liver problems are therefore advised not to take Simvastatin without consulting their doctor. They must also refrain from consuming alcohol while taking this medicine to get maximum benefit.
Q. Is Simvastatin safe to take?
Yes, Simvastatin is safe to use if used as prescribed by the doctor and if the doctor's instructions are followed. The side effects of this medicine are few and do not occur in everyone.

Ezetimibe

Q. Is Ezetimibe a blood thinner?
No, Ezetimibe is not a blood thinner. It belongs to cholesterol-lowering group of medicines. It is a medicine which is used along with lifestyle changes to reduce cholesterol levels and other fatty substances in the blood.
Q. What foods should be avoided while taking Ezetimibe?
Since Ezetimibe is meant to decrease blood cholesterol levels, for best results avoid foods which are high in calories like chips, burgers, fried food, etc. Eat a low-fat, low-cholesterol diet. Be sure to follow all exercise and dietary recommendations made by your doctor or dietician.
Q. Can Ezetimibe cause liver damage?
Ezetimibe, when used with another cholesterol-lowering medicine (statin), may commonly cause an increase in liver enzymes. However, if it is used alone, then chances of increase in liver enzymes are uncommon. Your doctor will get blood tests done to check your liver function before starting and during treatment with Ezetimibe.
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Q. Should Ezetimibe be taken at night?
You can take Ezetimibe at anytime of the day. Take it exactly as advised by your doctor. You can take it with or without food.
Q. Can I drink alcohol with Ezetimibe?
You should avoid alcohol while taking Ezetimibe since it may increase your risk of getting side effects in the liver. Discuss with your doctor if you have any concerns.
Q. Does Ezetimibe cause muscle pain?
Muscle pain may occur when Ezetimibe is used with a statin. It usually does not occur when Ezetimibe is used alone. Contact your doctor immediately if you experience unexplained muscle pain or weakness. This is because on rare occasions, muscle problems, including muscle breakdown which may result in kidney damage can be serious and may become a potentially fatal condition.
Q. Does Ezetimibe raise blood sugar?
No, Ezetimibe does not raise blood sugar levels. In fact, it may be helpful for patients with diabetes since it helps in improving insulin resistance and also kidney function. Ezetimibe has not been shown to have any direct effect on blood sugar levels.

Content on this page was last updated on 28 September, 2024, by Dr. Varun Gupta (MD Pharmacology)