R2-F 10 Tablet

Tablet
Rs.301for 1 strip(s) (10 tablets each)
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Composition FOR R2-F

Fenofibrate(145mg),Rosuvastatin(10mg)

food interaction for R2-F

alcohol interaction for R2-F

pregnancy interaction for R2-F

lactation interaction for R2-F

food
alcohol
pregnancy
lactation
R2-F 10 Tablet may be taken with or without food, but it is better to take it at a fixed time.
None
CAUTION
It is unsafe to consume alcohol with R2-F 10 Tablet.
UNSAFE
R2-F 10 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
UNSAFE
R2-F 10 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR R2-F

Fenofibrate(145mg)

Uses

Fenofibrate is used in the treatment of high cholesterol and high triglycerides.

How it works

Fenofibrate is a lipid lowering medication. It works by lowering the levels of triglycerides and "bad" cholesterol (LDL), while raising the levels of "good" cholesterol (HDL).

Common side effects

Abdominal pain, Diarrhea, Nausea, Headache, Flatulence, Vomiting, Increased liver enzymes, Increased creatine phosphokinase (CPK) level in blood, Back pain, Muscle pain, Inflammation of the nose, Rash, Urticaria, Muscle spasm, Muscle weakness, Gallstones, Low blood platelets, Pancreatic inflammation, Pulmonary embolism, Deep vein thrombosis (blood clot in the legs), Anemia (low number of red blood cells), Hypersensitivity, Photosensitivity, Muscle damage, Rhabdomyolysis, Hepatitis (viral infection of liver), Acute renal failure
Rosuvastatin(10mg)

Uses

Rosuvastatin is used in the treatment of high cholesterol, high triglycerides and prevention of heart attack and stroke.

How it works

Rosuvastatin is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required by the body to make cholesterol, thereby lowering "bad" cholesterol (LDL) and triglycerides and raising "good" cholesterol (HDL).

Common side effects

Muscle pain, Weakness, Headache, Abdominal pain, Dizziness, Joint pain, Nausea, Rash, Itching, Protein in urine, Anaphylactic reaction, Low blood platelets, Muscle damage, Rhabdomyolysis, Increased transaminase level in blood, Blood in urine, Jaundice, Systemic lupus erythematosus

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Expert advice FOR R2-F

  • It should be taken with food.
  • Avoid alcohol consumption while taking this medication.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Notify your doctor if you are more tired than usual, do not feel hungry, or if you have yellow eyes, skin or dark urine.
  • Inform your doctor if you experience muscle pain, tenderness, cramps, or weakness while taking Fenofibrate, particularly if it is accompanied by a fever.
  • Do not discontinue Fenofibrate without consulting your doctor even if you feel better.
  • Fenofibrate is the medication of choice for lowering triglyceride levels in the blood. It can reduce triglycerides by up to 50%.
  • It decreases the risk of heart disease and helps prevent stroke and heart attack.
  • Take it along with regular exercise and low-fat diet to lower levels of fat in the blood.
  • It should be taken with food.
  • Your doctor may check your liver function before starting treatment and regularly thereafter. Notify your doctor if you are more tired than usual, do not feel hungry, or if you have yellow eyes, skin or dark urine.
  • Avoid alcohol consumption while taking this medication.
  • Do not discontinue Fenofibrate without consulting your doctor even if you feel better.
  • Inform your doctor if you experience muscle pain, tenderness, cramps, or weakness while taking Fenofibrate, particularly if it is accompanied by a fever.

Frequently asked questions FOR R2-F

Fenofibrate

Q. When should Fenofibrate be taken?
Usually, Fenofibrate is taken once daily with a meal. The initial dose of the medicine will depend on the type and age of the patient. Consult your doctor before you start taking the medication and follow the instructions as provided.
Q. Does Fenofibrate raise blood pressure?
There is no or negligible effect on blood pressure in patients with normal blood pressure levels. However, Fenofibrate may lead to a decrease in blood pressure in patients with high blood pressure.
Q. Can Fenofibrate cause kidney problems?
Fenofibrate should be used with caution in patients with kidney disorders. Serum creatinine levels may increase with long-term usage of Fenofibrate but is completely reversible. The evidence of kidney damage with this medicine is rare still the kidney function blood test should be done regularly if there is a possibility of kidney damage. Consult your doctor before taking the medicine. Inform the doctor if you have had any disease and all the medicines that you are taking for a better diagnosis and treatment.
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Q. Can I take grapefruit juice with Fenofibrate?
Yes, you can take Fenofibrate with grapefruit juice. The possibility of interaction of the medicine with grapefruit is unlikely as they are broken down in our body by different enzymes. However, if in doubt then limit the intake of grapefruit juice while taking Fenofibrate.
Q. What drugs should not be taken with Fenofibrate?
There are few drugs like Oral Anticoagulants or blood thinners, ciclosporin, cholesterol-lowering medications like statins and contraceptives are contraindicated while you take Fenofibrate. Along with that, there are certain medicines which should not be taken with Fenofibrate and therefore you must give a proper history to your doctor regarding your ongoing medication. This is done to analyze the condition and provide a proper therapy and prescription which will help minimizing the side effects of the medication.

Rosuvastatin

Q. For how long should I take Rosuvastatin?
You may need to take Rosuvastatin for life or for as long as directed by your doctor. The cholesterol levels will be maintained only till you are taking Rosuvastatin. Stopping Rosuvastatin without starting a different treatment may increase your cholesterol levels again. This medicine has only a few side effects and is usually considered safe if taken as directed by the doctor.
Q. Does Rosuvastatin cause weight gain?
No, there is no evidence of Rosuvastatin causing weight gain. If you are taking Rosuvastatin and gaining weight, consult your doctor. The doctor may get some investigations done to know the reason for the weight gain.
Q. Does Rosuvastatin make you tired?
Yes, Rosuvastatin can make you feel tired. This is because it reduces the energy supply to the muscles in the body. However, the exact reason behind the phenomenon is unknown and needs more research. Tiredness usually occurs after exertion. Generalized fatigue is more often in people with heart disease or those suffering from liver illness. Rosuvastatin also causes muscle damage which further worsens the tiredness. Therefore, you must consult your doctor if you feel tired while taking Rosuvastatin.
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Q. Should Rosuvastatin be taken at night?
Rosuvastatin should be taken once a day. It can be taken in the morning or at night or any time of the day, with or without food. Try taking this medicine at the same time every day. Doing this will help you remember to take it daily.
Q. What foods should be avoided when taking Rosuvastatin?
Rosuvastatin is used to decrease your blood cholesterol levels. Therefore, to seek the best results of this medicine, you should avoid foods that are high in calories like fried food and junk food. It is recommended to eat a low-fat and low-cholesterol diet. Be sure to follow all the exercise and dietary recommendations made by your doctor or dietician.
Q. How do I know whether Rosuvastatin is beneficial for me or not?
All medicines have side effects, but the benefits of Rosuvastatin in reducing cholesterol levels and the risk of heart attack and stroke are proven by a large number of studies. However, if you do have any concerns, then discuss it with your doctor. Your doctor will consider and explain to you the benefits of taking Rosuvastatin versus the risks of not taking it at all.
Q. Can Rosuvastatin cause memory loss?
Rosuvastatin may cause memory loss in very rare cases. This is generally non-serious and may occur within 1 day of taking this medicine or may take years to appear. These symptoms may disappear within about 3 weeks of discontinuing Rosuvastatin. However, you should consult your doctor if you experience this side effect as it could be due to some other reason.
Q. Is it true that Rosuvastatin can cause diabetes?
If you are at high risk of developing type 2 diabetes, taking Rosuvastatin may slightly increase this risk. This is because Rosuvastatin has the potential to cause a slight increase in your blood sugar levels. If you already have type 2 diabetes, your doctor may advise you to keep monitoring your blood sugar levels closely for the first few months. Tell your doctor if you find it harder to control your blood sugar.
Q. Can I take alcohol with Rosuvastatin?
No. It is not advised to take alcohol with Rosuvastatin. This is because the risk of developing liver problems increases if you drink alcohol while taking this medicine. Moreover, there is a significant increase in the triglyceride levels if Rosuvastatin is taken along with alcohol. This can further lead to liver damage and also worsen some of the side effects such as muscle pain, muscle weakness and tenderness. People with liver problems are therefore advised, not to take Rosuvastatin without consulting their doctor. They must also refrain from consuming alcohol while taking this medicine to get maximum benefit.
Q. Can Rosuvastatin cause muscle problems or muscle injury?
Yes, taking Rosuvastatin can cause muscle problems or muscle injury. This is because of the reduced oxygen supply to the muscle cells which leads to fatigue, muscle pain, tenderness or muscle weakness. The soreness may be significant enough to interfere with your daily activities. Do not take it lightly and consult your doctor to know about ways to prevent this and to avoid making it worse.

Content on this page was last updated on 16 December, 2024, by Dr. Varun Gupta (MD Pharmacology)