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Prothiaden M 75mg/1500mcg Tablet

Tablet
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Composition FOR Prothiaden M

Dosulepin(75mg),Methylcobalamin(1500mcg)

food interaction for Prothiaden M

alcohol interaction for Prothiaden M

pregnancy interaction for Prothiaden M

lactation interaction for Prothiaden M

food
alcohol
pregnancy
lactation
Prothiaden M 75mg/1500mcg Tablet may be taken with or without food, but it is better to take it at a fixed time.
None
CAUTION
Prothiaden M 75mg/1500mcg Tablet may cause excessive drowsiness with alcohol.
UNSAFE
Prothiaden M 75mg/1500mcg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Prothiaden M 75mg/1500mcg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Prothiaden M

Dosulepin(75mg)

Uses

Dosulepin is used in the treatment of anxiety disorder and depression. It is used in patients intolerant of or unresponsive to alternative other treatment options for depression.

How it works

Dosulepin is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Common side effects

Dryness in mouth, Difficulty in urination, Constipation, Sweating, Dizziness, Tremors, Sedation, Loss of accommodation, Postural hypotension (low blood pressure), Tachycardia, Confusion, Hallucination, Bone marrow depression, Hepatitis (viral infection of liver), Convulsion, SIADH (water retention due to excessive ADH)
Methylcobalamin(1500mcg)

Uses

Methylcobalamin is used in vitamin B12 deficiency.

How it works

Methylcobalamin is a form of vitamin B12 that restores its level in the body thereby helping in treating certain anemias and nerve problems.

Common side effects

Decreased appetite, Diarrhea, Nausea, Rash

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Expert advice FOR Prothiaden M

  • It may take 4 to 6 weeks for Dosulepin to start working. Keep taking it as prescribed.
  • It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Dosulepin as it may cause excessive sleepiness.
  • Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.

Frequently asked questions FOR Prothiaden M

Dosulepin

Q. What is Dosulepin used for?
Dosulepin is a medicine used to treat anxiety disorder and depression that is unresponsive to other alternative medicines. It is also used to relieve nerve pain and fibromyalgia. Dosulepin should be taken only if prescribed by a doctor, exactly as directed.
Q. Is Dosulepin a muscle relaxant?
No. Dosulepin is not a muscle relaxant. It is a tricyclic antidepressant (TCA) used in the treatment of depression, nerve pain, and anxiety disorder.
Q. What is the difference between Dosulepin and amitriptyline?
Dosulepin is chemically related to Amitriptyline and both are tricyclic antidepressant (TCA) medicine. There is overlap in pharmacological property of this medicine.
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Q. Is Dosulepin the same as doxepin?
Dosulepin and doxepin are different medicines but belong to the similar chemical class. Doxepin, at low doses, can improve sleep in patients with insomnia. It is also available in the topical form for use in various neuro-dermatitis syndrome, especially itching.
Q. How to stop Dosulepin?
If your doctor asks you to stop Dosulepin, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly. Sudden discontinuation may cause aggression, anxiety, blurred vision, concentration impairment, constipation and crying spell.
Q. Is Dosulepin fatal?
Yes. Dosulepin can be fatal (can cause death) in overdose. This is due to a life-threatening or dangerous side effect in overdose like hyperthermia, seizure, arrhythmia, tachycardia, orthostatic hypotension or sudden death. That's why it is generally not considered a first-line option for depression because of side effect profile.
Q. Can I take Dosulepin with diazepam?
It is better to avoid this combination. Diazepam is a sedative drug and Dosulepin may cause sedation as a side effect too. Taking both of them together can increase the drowsiness or sleepiness. Inform your doctor if you are taking diazepam.
Q. Can Dosulepin be used in the treatment of trigeminal neuralgia?
No. Dosulepin is not approved for the treatment of trigeminal neuralgia. Trigeminal neuralgia is a chronic pain condition that affects the trigeminal or 5th cranial nerve, one of the most widely distributed nerves in the head.
Q. Can Dosulepin be used in the treatment of burning mouth syndrome?
No. Dosulepin is not approved for the treatment of burning mouth syndrome. Burning mouth syndrome is a painful condition of mouth that is burning, scalding, tingling or feeling of numbness that may occur every day for months or longer.
Q. Can I take Dosulepin for depression?
Yes. Dosulepin is indicated for the treatment of depression. It has a potential advantage in the patient with depression if associated with insomnia and anxiety. It is generally not considered a first-line option for depression because of side effect profile but very useful for severe or treatment-resistant depression.
Q. Can Dosulepin used to treat IBS (Irritable Bowel Syndrome)?
No. Dosulepin is not approved for the treatment of Irritable Bowel Syndrome (IBS). Irritable Bowel Syndrome is a functional gastrointestinal disorder characterised by chronic or recurrent abdominal pain or discomfort associated with altered bowel habits.
Q. Can Dosulepin be used to treat insomnia with depression?
Yes. Dosulepin may be used for the treatment of insomnia (too much arousal both at night and during the day) associated with depression. Because it can cause drowsiness or sedation as side effects, it is effective in treating insomnia associated with depression.
Q. Can I use Dosulepin for fibromyalgia?
Yes. Dosulepin is not approved for the treatment of fibromyalgia. Fibromyalgia is a pain syndrome with tenderness but no structural pathology in muscles, ligamanets or joints.
Q. Can I use Dosulepin for nerve pain?
Yes. Dosulepin is indicated for the treatment of nerve pain/neuropathic pain. Chronic pain/Neuropathic pain is described as pain that arises from damage to, or dysfunction of, any part of peripheral or central nervous system. It is associated with the disease which can affect nerves like diabetes mellitus or herpes infections.

Methylcobalamin

Q. What is Methylcobalamin?
Methylcobalamin contains vitamin B12. Vitamin B12 is an essential nutrient which is required by the body to make red blood cells and maintain a healthy nervous system. It is also important for releasing energy from food and using vitamin B11 (folic acid).
Q. Why can’t I get sufficient vitamin B12 from my diet?
You can get vitamin B12 from sources like meat, fish, eggs and dairy products. While people who are vegetarian or vegan may not get Vitamin B12 as it is not found naturally in foods such as fruits, vegetables and grains. Therefore, deficiency of Vitamin B12 is usually noticed in vegetarians or vegans.
Q. What happens if I have vitamin B12 deficiency?
Deficiency of vitamin B12 may cause tiredness, weakness, constipation, loss of appetite, weight loss and megaloblastic anemia (a condition when red blood cells become larger in size than normal). It may also lead to nerve problems such as numbness and tingling in the hands and feet. Other symptoms of vitamin B12 deficiency may include problems with balance, depression, confusion, dementia, poor memory and soreness of the mouth or tongue.
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Q. How should Methylcobalamin be taken?
Methylcobalamin should be taken in the dose and duration advised by your doctor. It can be taken with or without food. However, it would be best to take it at the same time each day to avoid the chances of missing a dose.
Q. What if I forget to take a dose of Methylcobalamin?
If you forget a dose of Methylcobalamin, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Q. Is Methylcobalamin safe?
Methylcobalamin is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Content on this page was last updated on 11 November, 2024, by Dr. Varun Gupta (MD Pharmacology)