Q. What is the difference between Pisi 20mg Tablet and ketoprofen?
Both Pisi 20mg Tablet and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Pisi 20mg Tablet. Ketoprofen gel also showed excellent tolerability.
Q. What is the difference between Pisi 20mg Tablet and tramadol?
Pisi 20mg Tablet is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Q. What is the difference between Pisi 20mg Tablet and nimesulide?
Both Pisi 20mg Tablet and nimesulide are pain killers. However, Pisi 20mg Tablet is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Q. Can Pisi 20mg Tablet be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Pisi 20mg Tablet or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Pisi 20mg Tablet.
Q. Are Pisi 20mg Tablet and aspirin same?
No. Pisi 20mg Tablet and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Q. Can Pisi 20mg Tablet be used along with dexamethasone?
No. Pisi 20mg Tablet should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Q. Can Pisi 20mg Tablet be used with methocarbamol?
Yes. Methocarbamol can be used with Pisi 20mg Tablet as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Can Pisi 20mg Tablet be used along with paracetamol?
Yes. Paracetamol can be used with Pisi 20mg Tablet as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Is Pisi 20mg Tablet a NSAID?
Yes. Pisi 20mg Tablet is a non-steroidal anti-inflammatory drug (NSAID).
Q. Is Pisi 20mg Tablet a sulfa drug?
Pisi 20mg Tablet is a sulphur containing compound. Pisi 20mg Tablet can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Q. Is Pisi 20mg Tablet a blood thinner?
No. Pisi 20mg Tablet is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Q. Is Pisi 20mg Tablet a muscle relaxant?
No. Pisi 20mg Tablet is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Q. Is Pisi 20mg Tablet a narcotic?
No. Pisi 20mg Tablet is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Q. Can Pisi 20mg Tablet be used in hypertension?
No. Pisi 20mg Tablet is not a medication to control hypertension. It is important to note that Pisi 20mg Tablet decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Pisi 20mg Tablet.
Q. Can Pisi 20mg Tablet be used along with Losartan?
No. Pisi 20mg Tablet should not be combined with Losartan. It is important to note that Pisi 20mg Tablet decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Pisi 20mg Tablet.
Q. Can Pisi 20mg Tablet be used with Lisinopril?
No. Pisi 20mg Tablet should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Pisi 20mg Tablet.
Q. Can Pisi 20mg Tablet be used with calcium channel blocker?
Yes. Pisi 20mg Tablet can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Q. Can Pisi 20mg Tablet be used with Tizanidine?
Yes, Pisi 20mg Tablet can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Q. Why is beta cyclodextrin added to Pisi 20mg Tablet?
Yes. Pisi 20mg Tablet can be combined with beta-cyclodextrin. Research has shown that combining Pisi 20mg Tablet with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Q. Are there any alternatives of Pisi 20mg Tablet?
Yes. There are alternatives to Pisi 20mg Tablet. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Q. What are the contraindications for Pisi 20mg Tablet?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Q. Can Pisi 20mg Tablet be used in the treatment of allergy?
No. Pisi 20mg Tablet is not a drug to treat allergy. It is a pain killer.
Q. How long does Pisi 20mg Tablet work?
Pisi 20mg Tablet is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Q. Can you get high by using Pisi 20mg Tablet?
No. Pisi 20mg Tablet is not known to cause high. It is a non-narcotic painkiller.
Q. Can Pisi 20mg Tablet be used to treat menstrual cramp?
Pisi 20mg Tablet is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Q. Can I use Pisi 20mg Tablet for a migraine?
Pisi 20mg Tablet is not approved for the treatment of migraine. Research studies have shown that Pisi 20mg Tablet is effective in significantly decreasing the pain associated with migraine without aura.
Q. Is Pisi 20mg Tablet effective in back pain management?
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Pisi 20mg Tablet as the cause of back pain can be different for different person.
Q. Is Pisi 20mg Tablet affective in gout management?
Yes. Pisi 20mg Tablet can be given for the treatment of acute gout. Research studies have shown Pisi 20mg Tablet to be highly effective in the treatment of acute gout.
Q. Can you donate blood when on the medication with Pisi 20mg Tablet?
Yes. You can donate blood when on Pisi 20mg Tablet. Do inform your doctor before donating blood.
Q. Can I use Pisi 20mg Tablet if I am a diabetic?
Pisi 20mg Tablet in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Pisi 20mg Tablet so taking piroxicam can lead to increased risk of renal failure by many folds.
Q. Can I use Pisi 20mg Tablet if I have a deranged renal function?
No. Pisi 20mg Tablet should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Q. Can Pisi 20mg Tablet lead to skin reactions?
Yes. Pisi 20mg Tablet is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Q. Can I use Pisi 20mg Tablet if I am pregnant?
No. Pisi 20mg Tablet should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Q. Can I use Pisi 20mg Tablet if I have peptic ulcer disease?
No. Pisi 20mg Tablet is contraindicated in cases of active peptic ulcer disease. Pisi 20mg Tablet is known to cause gastric ulceration and bleeding.
Q. Can I use Pisi 20mg Tablet if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. Can Pisi 20mg Tablet lead to difficulty in conception?
Yes. Pisi 20mg Tablet can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Can Pisi 20mg Tablet be used with diuretics?
No. Pisi 20mg Tablet should not be used with diuretics. Pisi 20mg Tablet reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can Pisi 20mg Tablet be used with lithium?
No. Pisi 20mg Tablet should not be used with lithium. Pisi 20mg Tablet leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Q. Can Pisi 20mg Tablet be used with warfarin?
No. Pisi 20mg Tablet should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Q. What increases the chances of getting a gastric ulcer when I am already taking Pisi 20mg Tablet?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Pisi 20mg Tablet?
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Q. What are the serious side effects of Pisi 20mg Tablet?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
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