Q. What is the difference between Pirospey 40 Injection and ketoprofen?
Both Pirospey 40 Injection and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Pirospey 40 Injection. Ketoprofen gel also showed excellent tolerability.
Q. What is the difference between Pirospey 40 Injection and tramadol?
Pirospey 40 Injection is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Q. What is the difference between Pirospey 40 Injection and nimesulide?
Both Pirospey 40 Injection and nimesulide are pain killers. However, Pirospey 40 Injection is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Q. Can Pirospey 40 Injection be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Pirospey 40 Injection or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Pirospey 40 Injection.
Q. Are Pirospey 40 Injection and aspirin same?
No. Pirospey 40 Injection and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Q. Can Pirospey 40 Injection be used along with dexamethasone?
No. Pirospey 40 Injection should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Q. Can Pirospey 40 Injection be used with methocarbamol?
Yes. Methocarbamol can be used with Pirospey 40 Injection as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Can Pirospey 40 Injection be used along with paracetamol?
Yes. Paracetamol can be used with Pirospey 40 Injection as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Is Pirospey 40 Injection a NSAID?
Yes. Pirospey 40 Injection is a non-steroidal anti-inflammatory drug (NSAID).
Q. Is Pirospey 40 Injection a sulfa drug?
Pirospey 40 Injection is a sulphur containing compound. Pirospey 40 Injection can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Q. Is Pirospey 40 Injection a blood thinner?
No. Pirospey 40 Injection is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Q. Is Pirospey 40 Injection a muscle relaxant?
No. Pirospey 40 Injection is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Q. Is Pirospey 40 Injection a narcotic?
No. Pirospey 40 Injection is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Q. Can Pirospey 40 Injection be used in hypertension?
No. Pirospey 40 Injection is not a medication to control hypertension. It is important to note that Pirospey 40 Injection decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Pirospey 40 Injection.
Q. Can Pirospey 40 Injection be used along with Losartan?
No. Pirospey 40 Injection should not be combined with Losartan. It is important to note that Pirospey 40 Injection decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Pirospey 40 Injection.
Q. Can Pirospey 40 Injection be used with Lisinopril?
No. Pirospey 40 Injection should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Pirospey 40 Injection.
Q. Can Pirospey 40 Injection be used with calcium channel blocker?
Yes. Pirospey 40 Injection can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Q. Can Pirospey 40 Injection be used with Tizanidine?
Yes, Pirospey 40 Injection can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Q. Why is beta cyclodextrin added to Pirospey 40 Injection?
Yes. Pirospey 40 Injection can be combined with beta-cyclodextrin. Research has shown that combining Pirospey 40 Injection with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Q. Are there any alternatives of Pirospey 40 Injection?
Yes. There are alternatives to Pirospey 40 Injection. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Q. What are the contraindications for Pirospey 40 Injection?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Q. Can Pirospey 40 Injection be used in the treatment of allergy?
No. Pirospey 40 Injection is not a drug to treat allergy. It is a pain killer.
Q. How long does Pirospey 40 Injection work?
Pirospey 40 Injection is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Q. Can you get high by using Pirospey 40 Injection?
No. Pirospey 40 Injection is not known to cause high. It is a non-narcotic painkiller.
Q. Can Pirospey 40 Injection be used to treat menstrual cramp?
Pirospey 40 Injection is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Q. Can I use Pirospey 40 Injection for a migraine?
Pirospey 40 Injection is not approved for the treatment of migraine. Research studies have shown that Pirospey 40 Injection is effective in significantly decreasing the pain associated with migraine without aura.
Q. Is Pirospey 40 Injection effective in back pain management?
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Pirospey 40 Injection as the cause of back pain can be different for different person.
Q. Is Pirospey 40 Injection affective in gout management?
Yes. Pirospey 40 Injection can be given for the treatment of acute gout. Research studies have shown Pirospey 40 Injection to be highly effective in the treatment of acute gout.
Q. Can you donate blood when on the medication with Pirospey 40 Injection?
Yes. You can donate blood when on Pirospey 40 Injection. Do inform your doctor before donating blood.
Q. Can I use Pirospey 40 Injection if I am a diabetic?
Pirospey 40 Injection in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Pirospey 40 Injection so taking piroxicam can lead to increased risk of renal failure by many folds.
Q. Can I use Pirospey 40 Injection if I have a deranged renal function?
No. Pirospey 40 Injection should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Q. Can Pirospey 40 Injection lead to skin reactions?
Yes. Pirospey 40 Injection is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Q. Can I use Pirospey 40 Injection if I am pregnant?
No. Pirospey 40 Injection should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Q. Can I use Pirospey 40 Injection if I have peptic ulcer disease?
No. Pirospey 40 Injection is contraindicated in cases of active peptic ulcer disease. Pirospey 40 Injection is known to cause gastric ulceration and bleeding.
Q. Can I use Pirospey 40 Injection if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. Can Pirospey 40 Injection lead to difficulty in conception?
Yes. Pirospey 40 Injection can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Can Pirospey 40 Injection be used with diuretics?
No. Pirospey 40 Injection should not be used with diuretics. Pirospey 40 Injection reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can Pirospey 40 Injection be used with lithium?
No. Pirospey 40 Injection should not be used with lithium. Pirospey 40 Injection leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Q. Can Pirospey 40 Injection be used with warfarin?
No. Pirospey 40 Injection should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Q. What increases the chances of getting a gastric ulcer when I am already taking Pirospey 40 Injection?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Pirospey 40 Injection?
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Q. What are the serious side effects of Pirospey 40 Injection?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
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