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Mizral DZ 2.5mg/20mg Tablet

Tablet
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Composition FOR Mizral DZ

Diazepam(2.5mg),Propranolol(20mg)

food interaction for Mizral DZ

alcohol interaction for Mizral DZ

pregnancy interaction for Mizral DZ

lactation interaction for Mizral DZ

food
alcohol
pregnancy
lactation
Mizral DZ 2.5mg/20mg Tablet is to be taken empty stomach.
Take this medicine before food.
None
CAUTION
It is unsafe to consume alcohol with Mizral DZ 2.5mg/20mg Tablet.
UNSAFE
Mizral DZ 2.5mg/20mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
Mizral DZ 2.5mg/20mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Mizral DZ 2.5mg/20mg Tablet should be used for short periods and sleepiness of the baby should be watched. The withdrawal of Mizral DZ 2.5mg/20mg Tablet should be gradual.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Mizral DZ

Diazepam(2.5mg)

Uses

Diazepam is used in the treatment of short term anxiety, alcohol withdrawal, muscle spasm and epilepsy.

How it works

Diazepam is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Common side effects

Drowsiness, Fatigue, Confusion, Depression, Dizziness, Dryness in mouth, Headache, Impaired concentration, Slurred speech, Urinary retention, Abnormality of voluntary movements, Sensory motor disorders, Tremors, Withdrawal symptoms, Anterograde amnesia, Balance disorder (loss of balance), Respiratory depression, Allergic skin condition, Gastrointestinal disorder, Salivary hypersecretion, Myasthenia (weakness and rapid fatigue of muscle), Blood dyscrasias, Insomnia (difficulty in sleeping), Loss of consciousness, Psychiatric disturbances, Paradoxical reactions, Emotional lability, Change in alertness, Heart failure, Hypotension (low blood pressure), Increased appetite, Abnormal liver function tests, Vision disorder, Apnea (absence of breathing), Anaphylactic reaction
Propranolol(20mg)

Uses

Propranolol is used in the treatment of Angina (heart-related chest pain), Hypertension (high blood pressure), Arrhythmia, heart attack, Anxiety, Tremors, glaucoma, Heart failure, Prevention of migraine, migraine and Pheochromocytoma.

How it works

Propranolol contains Propranolol, a beta blocker. It works by affecting the body’s response to nerve impulses, especially in the heart. It slows down your heart rate and makes it easier for the heart to pump blood around the body. This prevents arrhythmia, stabilizes blood pressure and prevents a heart attack. It also widens the blood vessels in the body for better blood flow, thereby preventing angina as well as migraine. The exact mechanism by which it prevents tremors is not known, but experts believe that Propranolol helps block the nerve impulses to the muscles responsible for tremors. Propranolol helps block the effects of the chemical messengers namely, adrenaline and noradrenaline, that are produced by the brain and are responsible for increasing your heart rate which makes you feel anxious. This way it helps with anxiety. While treating pheochromocytoma, Propranolol may be given to block the action of high-adrenaline hormones, to lower the risk of developing dangerously high blood pressure during surgery for removing the tumor.

Common side effects

Sleep disturbance, Fatigue, Low blood platelets, Psychosis, Mood changes, Hallucination, Myasthenia gravis, Slow heart rate, Nightmares, Cold extremities, Paresthesia (tingling or pricking sensation), Hair loss, Purpura

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Expert advice FOR Mizral DZ

  • Diazepam helps treat short term anxiety.
  • Safety of this medicine is not established for long-term use. Do not use it for more than 4 weeks. 
  • The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Avoid consuming alcohol as it may increase dizziness and drowsiness.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.

Frequently asked questions FOR Mizral DZ

Diazepam

Q. Is Diazepam an antidepressant? What is it used for?
Diazepam is not an antidepressant and belongs to a group of medicines called benzodiazepine. It is used to treat severe anxiety (an emotional state where you may sweat, tremble, feel anxious and have a fast heartbeat) or agitation. It is also used to treat trembling, muscle spasm due to tetanus or poisoning, seizures or fits, confusional states or anxiety associated with alcohol withdrawal. It also helps in relaxing patients before minor operations or procedures.
Q. How long does it take for Diazepam to start working?
It depends on what you are taking Diazepam for. If you are taking it to treat anxiety, you should start feeling better within a few hours, but it may take a week or two before the full benefits become evident. Similarly, if you are taking it to relieve muscle spasm you may notice a difference after 15 minutes. Your muscles will start relaxing when you keep taking Diazepam regularly for a few days.
Q. Does Diazepam cause sleepiness? If yes, then should I stop driving while taking Diazepam?
Yes, Diazepam causes drowsiness very commonly. It also causes forgetfulness and affects muscular function which may adversely affect your ability to drive. Sometimes, drowsiness persists even on the following day. So, in case Diazepam makes you sleepy and affects your alertness, you should avoid driving.
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Q. Is it safe to take Diazepam and alcohol together?
No, it is not at all recommended to take alcohol with Diazepam since it can cause breathing problems, sleepiness and heart problems. Taking Diazepam with alcohol may make you sleepy and your breathing may become so shallow that you may not wake up. This may even lead to death.
Q. Is Diazepam addictive?
People taking Diazepam in high doses or for a long term may become addicted to it. Also, people with a history of alcoholism and drug abuse are more likely to become addicted to Diazepam. Therefore, Diazepam should be taken for the shortest possible time and in the lowest effective dose.
Q. Can I stop taking Diazepam if I start feeling better?
No, do not stop taking Diazepam suddenly as you may experience withdrawal effects like depression, nervousness, difficulty in sleeping, irritability, sweating, upset stomach or diarrhea. Stopping it suddenly may even bring back the symptoms and make them harder to treat. You may also experience mood changes, anxiety, restlessness and changes in sleep patterns. These effects may occur even after taking low doses for a short period of time.
Q. For how long should I take Diazepam?
The duration of treatment with Diazepam is mainly as short as possible. Your doctor will evaluate you after 4 weeks of treatment in order to assess the need of continuation of treatment, especially if you do not have any symptoms. In general, the treatment does not last any longer than 8-12 weeks which includes the gradual reduction of dose process.
Q. Does Diazepam have any effect on contraception?
Diazepam does not affect the functioning of any type of contraception including the birth control pills and emergency contraception. Birth control pills can keep Diazepam in your body for a long time and increase its effect. You can also experience bleeding in between your periods if you take Diazepam and birth control pills together. But your contraceptive method will still work.
Q. Is it safe to take clozapine and Diazepam together?
No, it is not recommended to take clozapine and Diazepam together because the effects of both medicines may get added together. This can result in severe drop in blood pressure, breathing problems (respiratory depression) and can even stop your heart which can lead to death.
Q. Is Diazepam safe to be used in elderly patients?
The dose in elderly is generally half of the dose recommended to young people. This is because Diazepam causes muscle relaxation which can make the patient fall down, which may further lead to fractures.

Propranolol

Q. My doctor has prescribed Propranolol even though my blood pressure is within normal limits. Is it because of the chest pain that I complained of?
Yes, it is possible that your doctor prescribed Propranolol for chest pain (angina). Propranolol is a beta-blocker that is used to lower high blood pressure, prevent angina, treat or prevent heart attacks or reduce your risk of heart problems following a heart attack. Propranolol is also used to treat irregularities in the heartbeat, including those caused by anxiety, essential tremor (shaking of the head, chin and hands). It also prevents migraine headaches, overactive thyroid (thyrotoxicosis and hyperthyroidism), and bleeding in the food pipe caused by high blood pressure.
Q. When can I expect relief in my symptoms after starting Propranolol for high blood pressure?
Propranolol usually starts working within a few hours of taking it. However, it may take up to a week to see the full benefits of the symptoms of high blood pressure or heart conditions. You may not notice any difference, but that does not mean it is not working. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.
Q. Can Propranolol be used in asthmatics?
No, Propranolol cannot be used in asthmatics. This is because using Propranolol in asthma patients can cause breathing problems, which may trigger an asthma attack. Always inform your doctor if you have or ever had asthma or any episodes of difficulty breathing, before starting treatment with Propranolol.
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Q. What if I forget to take a dose of Propranolol?
If you forget a dose of Propranolol, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose at the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
Q. Can I stop taking Propranolol as my chest pain is under control?
No, you should not stop taking Propranolol suddenly because that may worsen your angina or may cause a heart attack. Tell your doctor and if there is a need to stop Propranolol, your doctor will reduce your dose gradually over a period of a few weeks.
Q. Does Propranolol relieve anxiety?
Yes, Propranolol helps relieve the symptoms of anxiety such as irritability, restlessness, excessive worry, lack of concentration, racing or unwanted thoughts, fatigue, insomnia (lack of sleep), palpitations (irregular heart rate), or trembling. The dose and duration of taking Propranolol will be suggested by your doctor, depending on whether your symptoms are a recurring problem or occur only in stressful conditions. However, Propranolol is usually given for the short-term treatment of anxiety. If you have any doubts, consult your doctor.
Q. What other lifestyle changes should I make while taking Propranolol?
Lifestyle changes play a major role in keeping you healthy if you are taking Propranolol. Avoid taking excess salt in your diet and find ways to reduce or manage stress in your life. Practice yoga or meditation or take up a hobby. Ensure that you have a sound sleep every night as this also helps to reduce stress levels and helps to keep your blood pressure normal. Stop smoking and alcohol consumption as this helps in lowering your blood pressure and preventing heart problems. Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables, and fat-free products. Consult your doctor if you need any further guidance to get the maximum benefit of Propranolol and to keep yourself healthy.
Q. Is Propranolol effective?
Propranolol is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Propranolol too early, the symptoms may return or worsen.
Q. What if I take an overdose of Propranolol?
If you take an overdose of Propranolol you may experience symptoms such as slow heartbeat, trembling, difficulty breathing, or dizziness. However, the response of taking too much of Propranolol varies from person to person. It would be best to consult a doctor if you think you have taken more than what you are prescribed.
Q. Is Propranolol safe?
Propranolol is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Q. I have been on Indomethacin for several months. Will it be a problem if I start taking Propranolol along with it?
Yes, Indomethacin may interfere with the working of Propranolol and make it less effective. As a result, your blood pressure may increase. Speak to your doctor who will prescribe you a different medicine to control blood pressure.

Content on this page was last updated on 06 November, 2024, by Dr. Varun Gupta (MD Pharmacology)