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Manogrel RT 20mg/75mg Tablet

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Composition FOR Manogrel RT

Rosuvastatin(20mg),Clopidogrel(75mg)

food interaction for Manogrel RT

alcohol interaction for Manogrel RT

pregnancy interaction for Manogrel RT

lactation interaction for Manogrel RT

food
alcohol
pregnancy
lactation
Manogrel RT 20mg/75mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
None
CAUTION
It is unsafe to consume alcohol with Manogrel RT 20mg/75mg Tablet.
UNSAFE
Manogrel RT 20mg/75mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
UNSAFE
Manogrel RT 20mg/75mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Manogrel RT

Rosuvastatin(20mg)

Uses

Rosuvastatin is used in the treatment of high cholesterol, high triglycerides and prevention of heart attack and stroke.

How it works

Rosuvastatin is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required by the body to make cholesterol, thereby lowering "bad" cholesterol (LDL) and triglycerides and raising "good" cholesterol (HDL).

Common side effects

Muscle pain, Weakness, Headache, Abdominal pain, Dizziness, Joint pain, Nausea, Rash, Itching, Protein in urine, Anaphylactic reaction, Low blood platelets, Muscle damage, Rhabdomyolysis, Increased transaminase level in blood, Blood in urine, Jaundice, Systemic lupus erythematosus
Clopidogrel(75mg)

Uses

Clopidogrel is used for heart attack, peripheral vascular disease, unstable angina and prevention of heart attack and stroke. It decreases the chances of having another heart attack or stroke in people at high risk of heart disease.

How it works

Clopidogrel is an antiplatelet medication. It works by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clots. This lowers the chance of heart attack or stroke.

Common side effects

Abdominal pain, Stomach inflammation, Constipation, Skin rash, Blood in urine, Thrombotic thrombocytopenic purpura, Decreased blood cells (red cells, white cells, and platelets), Agranulocytosis (deficiency of granulocytes in the blood), Acquired hemophilia A, Vasculitis, Hypotension (low blood pressure), Aplastic anemia, Hypoglycemia (low blood glucose level), Hemorrhage, Vomiting, Nausea, Headache, Bruise, Dizziness, Diarrhea, Hematoma, Nosebleeds, Gastrointestinal bleeding, Dyspepsia, Low blood platelets, Intracranial bleeding, Stomach ulcer, Duodenal ulcer, Anaphylactic reaction

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Cholesterol - HDLCholesterol - TotalCholesterol - LDLTriglycerides
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Expert advice FOR Manogrel RT

  • Rosuvastatin treats high cholesterol by lowering "bad" cholesterol (LDL) and triglycerides (fats). It should be taken in addition to regular exercise and low-fat diet.
  • In general, Rosuvastatin is safe. It may cause diarrhea, gas or an upset stomach. If any of these happen to you, take it with food.
  • Inform your doctor if you experience fatigue, muscle weakness or muscle pain. 
  • Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of liver problems such as stomach pains, unusually dark urine or yellowing of skin or eyes.
  • Inform your doctor if you have kidney disease, liver disease or diabetes before starting treatment with this medicine. If you are diabetic, monitor your blood sugar level regularly as Rosuvastatin may cause an increase in your blood sugar level.
  • Do not take Rosuvastatin if you are pregnant, planning a pregnancy or breastfeeding.
  • Rosuvastatin treats high cholesterol by lowering "bad" cholesterol (LDL) and triglycerides (fats). It should be taken in addition to regular exercise and low-fat diet.
  • It also reduces the risk of heart attack and stroke.
  • In general, Rosuvastatin is safe. It may cause diarrhea, gas or an upset stomach. If any of these happen to you, take it with food.
  • Inform your doctor if you experience fatigue, muscle weakness or muscle pain. 
  • Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of liver problems such as stomach pains, unusually dark urine or yellowing of skin or eyes.
  • Inform your doctor if you have kidney disease, liver disease or diabetes before starting treatment with this medicine. If you are diabetic, monitor your blood sugar level regularly as Rosuvastatin may cause an increase in your blood sugar level.
  • Do not take Rosuvastatin if you are pregnant, planning a pregnancy or breastfeeding.

Frequently asked questions FOR Manogrel RT

Rosuvastatin

Q. For how long should I take Rosuvastatin?
You may need to take Rosuvastatin for life or for as long as directed by your doctor. The cholesterol levels will be maintained only till you are taking Rosuvastatin. Stopping Rosuvastatin without starting a different treatment may increase your cholesterol levels again. This medicine has only a few side effects and is usually considered safe if taken as directed by the doctor.
Q. Does Rosuvastatin cause weight gain?
No, there is no evidence of Rosuvastatin causing weight gain. If you are taking Rosuvastatin and gaining weight, consult your doctor. The doctor may get some investigations done to know the reason for the weight gain.
Q. Does Rosuvastatin make you tired?
Yes, Rosuvastatin can make you feel tired. This is because it reduces the energy supply to the muscles in the body. However, the exact reason behind the phenomenon is unknown and needs more research. Tiredness usually occurs after exertion. Generalized fatigue is more often in people with heart disease or those suffering from liver illness. Rosuvastatin also causes muscle damage which further worsens the tiredness. Therefore, you must consult your doctor if you feel tired while taking Rosuvastatin.
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Q. Should Rosuvastatin be taken at night?
Rosuvastatin should be taken once a day. It can be taken in the morning or at night or any time of the day, with or without food. Try taking this medicine at the same time every day. Doing this will help you remember to take it daily.
Q. What foods should be avoided when taking Rosuvastatin?
Rosuvastatin is used to decrease your blood cholesterol levels. Therefore, to seek the best results of this medicine, you should avoid foods that are high in calories like fried food and junk food. It is recommended to eat a low-fat and low-cholesterol diet. Be sure to follow all the exercise and dietary recommendations made by your doctor or dietician.
Q. How do I know whether Rosuvastatin is beneficial for me or not?
All medicines have side effects, but the benefits of Rosuvastatin in reducing cholesterol levels and the risk of heart attack and stroke are proven by a large number of studies. However, if you do have any concerns, then discuss it with your doctor. Your doctor will consider and explain to you the benefits of taking Rosuvastatin versus the risks of not taking it at all.
Q. Can Rosuvastatin cause memory loss?
Rosuvastatin may cause memory loss in very rare cases. This is generally non-serious and may occur within 1 day of taking this medicine or may take years to appear. These symptoms may disappear within about 3 weeks of discontinuing Rosuvastatin. However, you should consult your doctor if you experience this side effect as it could be due to some other reason.
Q. Is it true that Rosuvastatin can cause diabetes?
If you are at high risk of developing type 2 diabetes, taking Rosuvastatin may slightly increase this risk. This is because Rosuvastatin has the potential to cause a slight increase in your blood sugar levels. If you already have type 2 diabetes, your doctor may advise you to keep monitoring your blood sugar levels closely for the first few months. Tell your doctor if you find it harder to control your blood sugar.
Q. Can I take alcohol with Rosuvastatin?
No. It is not advised to take alcohol with Rosuvastatin. This is because the risk of developing liver problems increases if you drink alcohol while taking this medicine. Moreover, there is a significant increase in the triglyceride levels if Rosuvastatin is taken along with alcohol. This can further lead to liver damage and also worsen some of the side effects such as muscle pain, muscle weakness and tenderness. People with liver problems are therefore advised, not to take Rosuvastatin without consulting their doctor. They must also refrain from consuming alcohol while taking this medicine to get maximum benefit.
Q. Can Rosuvastatin cause muscle problems or muscle injury?
Yes, taking Rosuvastatin can cause muscle problems or muscle injury. This is because of the reduced oxygen supply to the muscle cells which leads to fatigue, muscle pain, tenderness or muscle weakness. The soreness may be significant enough to interfere with your daily activities. Do not take it lightly and consult your doctor to know about ways to prevent this and to avoid making it worse.

Clopidogrel

Q. What is Clopidogrel used for?
Clopidogrel is used to prevent formation of blood clots, thus reducing the risk of heart attacks or stroke. It facilitates smooth circulation of blood in the body by reducing the ability of the platelets to stick together, that could otherwise lead to formation of harmful clots in hardened blood vessels.
Q. Is Clopidogrel a blood thinner?
Yes, Clopidogrel is an antiplatelet medicine which is also known as a blood thinner. It makes your blood flow more easily through your blood vessels and prevents formation of harmful blood clots. This lowers your chances of heart attack or stroke.
Q. When should you take Clopidogrel?
You should take Clopidogrel exactly as prescribed by the doctor. You can take it with or without food, at any time of the day. However, it is important to take it regularly at the same time each day for best results. This will also help you to remember to take it daily.
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Q. Does Clopidogrel affect blood pressure?
Yes, Clopidogrel may rarely cause a decrease in blood pressure as a side effect. However, this is very rare and does not affect everyone. Consult your doctor if you feel dizzy, lightheaded, weak or have a blurred vision. These are signs and symptoms of low blood pressure and therefore, you should contact your doctor immediately.
Q. Who should not take Clopidogrel?
Clopidogrel is not recommended for people who are allergic to it, have severe liver disease, have stomach ulcers, bleeding in the brain, or have a bleeding disorder known as hemophilia (disease in which blood does not clot normally).
Q. Can Omeprazole be taken along with Clopidogrel?
Omeprazole ( a proton pump inhibitor or PPI used to treat and prevent indigestion) may interfere with the working of Clopidogrel and reduce the effect of Clopidogrel. Your doctor may prescribe an alternate PPI like lansoprazole, if you suffer from indigestion or if they judge that it would be beneficial to you. You should let your doctor know about all the medicines that have been prescribed to you before starting Clopidogrel. Always consult your doctor before taking any medicine.
Q. What will happen if I stop taking Clopidogrel?
If you stop taking Clopidogrel suddenly, your chances of heart attack or stroke may increase. These conditions can be fatal. Do not stop taking it without talking to your doctor, otherwise your condition may worsen. Continue taking Clopidogrel for as long as prescribed by your doctor to get maximum benefit.
Q. How long does it take Clopidogrel to start working? How long do I need to take it?
Clopidogrel starts working within 2 hours of taking it. Continue taking it as long as your doctor has advised you. You may have to take it for a few weeks or months, or you may have to take it for the rest of your life.
Q. What are the side effects of taking Clopidogrel?
The most common side effect of Clopidogrel is bleeding. This may lead to bruising on the skin, nosebleeds, blood in the urine or stools (black tarry stools), or heavier periods than usual in females. Rarely, bleeding may also occur in the head, eyes, lungs, or joints and may even be severe. In case you have a minor injury, such as a small cut while shaving, bleeding may take longer than usual to stop. Get emergency medical help if the bleeding is profuse, does not stop on it’s own, or bothers you. Other side effects of Clopidogrel that may be seen occasionally in some people include diarrhea, abdominal pain, indigestion or heartburn. Please consult your doctor if any of these side effects persist or worry you.
Q. Can I take alcohol with Clopidogrel?
Yes, you can take alcohol with Clopidogrel. However, excessive intake of alcohol should be avoided as it can irritate the inner lining of the stomach and this increases the risk of developing a stomach ulcer later.

Content on this page was last updated on 18 November, 2024, by Dr. Varun Gupta (MD Pharmacology)