Letfirst Tablet

Tablet
Rs.92for 1 strip(s) (5 tablets each)
1
Unfortunately, we don't have any more items in stock
Report Error

Composition FOR Letfirst 2.5mg Tablet

Letrozole(2.5mg)

food interaction for Letfirst Tablet

alcohol interaction for Letfirst Tablet

pregnancy interaction for Letfirst Tablet

lactation interaction for Letfirst Tablet

food
alcohol
pregnancy
lactation
Letfirst Tablet may be taken with or without food, but it is better to take it at a fixed time.
None
CAUTION
Consuming alcohol with Letfirst Tablet does not cause any harmful side effects.
SAFE
Letfirst Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
UNSAFE
Letfirst Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
UNSAFE

SALT INFORMATION FOR Letfirst 2.5mg Tablet

Letrozole(2.5mg)

Letfirst tablet uses

{med_name} is used in the treatment of breast cancer.

How letfirst tablet works

Letfirst Tablet is an aromatase inhibitor. It works by decreasing the amount of estrogen (natural female hormone) produced in the body. This decrease in estrogen can slow down or stop the growth of some breast cancers that need estrogen to grow.

Common side effects of letfirst tablet

Vaginal irritation, Lymphedema, Second primary malignant neoplasm, Transient ischemic attacks, Weakness, Breast pain, Vaginal bleeding, Joint inflammation, Vomiting, Muscle pain, Insomnia (difficulty in sleeping), Peripheral edema, Dizziness, Fatigue, Bone pain, Constipation, Back pain, Night sweats, Joint pain, Nausea, Osteoporosis, Pain, Hair loss, Cerebrovascular accident, Cough, Shortness of breath, Heart attack, Infection, Influenza, Hemiparesis (weakness on one side of the body), Lethargy, General discomfort, Reduction in bone density, Renal dysfunction, Ischemic heart disease, Ovarian cysts, Endometrial hyperplasia, Endometrial carcinoma (cancer of uterus), Low blood platelets, Weight gain, Hot flushes, Edema (swelling), Flushing (sense of warmth in the face, ears, neck and trunk), Diaphoresis, Weight loss, Brain hemorrhage, Thromboembolism, Thrombotic stroke, Bone fracture, Urinary tract infection, Chest pain, Decreased appetite, Hypercholesterolemia (high cholesterol), Headache, Diarrhea, Depression, High blood pressure, Angina pectoris, Heart failure

SUBSTITUTES FOR Letfirst Tablet

199 Substitutes
199 Substitutes
Sorted By
RelevancePrice
  • Letroz Tablet
    (5 tablets in strip)
    Rs. 30/Tablet
    Tablet
    Rs. 156.54
    pay 63% more per Tablet
  • Stimufol 2.5mg Tablet
    (5 tablets in strip)
    Rs. 30.80/Tablet
    Tablet
    Rs. 156.61
    pay 67% more per Tablet
  • Fempro Tablet
    (10 tablets in strip)
    Rs. 5.38/Tablet
    Tablet
    Rs. 85.35
    save 71% more per Tablet
  • Mamazol Tablet
    (10 tablets in strip)
    Rs. 16.70/Tablet
    Tablet
    Rs. 170.60
    save 9% more per Tablet
  • LETero Tablet
    (10 tablets in strip)
    Rs. 8.29/Tablet
    Tablet
    Rs. 82.90
    save 55% more per Tablet

Expert advice FOR Letfirst Tablet

  • You have been prescribed Letrozole for the treatment of breast cancer.
  • It can be taken with or without food.
  • Do not drive or do anything requiring concentration until you know how Letrozole affects you.
  • It may cause increased sweating and hot flushes. Try to keep cool by wearing light and airy clothes.
  • Your doctor may monitor your cholesterol level and bone mineral density (BMD) regularly as Letrozole can alter their levels.
  • Do not take Letrozole if you are pregnant or breastfeeding 

Frequently asked questions FOR Letfirst 2.5mg Tablet

Letrozole

Q. Why have I been prescribed Letfirst Tablet?
Letfirst Tablet is an aromatase inhibitor. It is generally prescribed to treat breast cancer in women who no longer have periods, either due to menopause or after surgery or chemotherapy.
Q. How does Letfirst Tablet work?
Letfirst Tablet is also known as an anti-estrogen drug. It is called so because it acts by reducing the production of estrogen in your body by blocking the enzyme aromatase, which is responsible for the production of estrogen. Estrogen stimulates the production of certain types of breast cancer in your body. These cancers are called "estrogen-dependent cancers". Reducing the production of estrogen may prevent cancer from growing.
Q. For how long should I take Letfirst Tablet?
If the breast tumor is in the advanced stage or has spread to other parts of the body, it is recommended that you continue taking Letfirst Tablet till the tumor shows progression. In cases where Letfirst Tablet is given after tamoxifen (another anti-estrogen used for breast cancer) or surgery, it should be given for 5 years or until the tumor comes back, whichever is first. It can also be given as a sequential treatment; 2 years of Letfirst Tablet followed by 3 years of tamoxifen.
Show More
Q. If I am taking irbesartan to control my blood pressure, can I take Letfirst Tablet?
Yes, you can take irbesartan and Letfirst Tablet together. However, be careful and keep a regular check on your blood pressure since Letfirst Tablet may increase your blood pressure. Consult your doctor in case you have problems controlling your blood pressure.
Q. Does Letfirst Tablet affect vision?
Although it is very uncommon, Letfirst Tablet may cause a cataract. So, if you experience blurred vision or eye irritation, consult your doctor immediately.
Q. My friend who is taking Letfirst Tablet often sweats a lot. Is it because of Letfirst Tablet?
This could be a sign of hot flushes which is a very common side effect of Letfirst Tablet. It happens due to decreased estrogen levels. The frequency of hot flushes reduces once your body adjusts to Letfirst Tablet. However, in some people, the flushes and sweats may continue during the treatment and stop a few months after the treatment finishes. You can consult your doctor who will provide you a remedy if it is very bothersome.
Q. What are the serious side effects of Letfirst Tablet?
The serious side effects do not occur in everyone and very few people experience them. The serious side effects of Letfirst Tablet include stroke, angina, heart attack, blood clotting, cataract, osteoporosis, and severe skin reactions.
Q. Does Letfirst Tablet cause bone loss?
Letfirst Tablet may cause thinning or wasting of your bones (osteoporosis), which is due to the decrease in estrogen levels in your body. Your doctor may decide to measure your bone density (a way of monitoring for osteoporosis) before, during and after treatment.
Q. Can I take Letfirst Tablet for induction of ovulation in anovulatory infertility?
As per the Ministry of Health and Family Welfare, Letfirst Tablet is restricted for use in induction of ovulation in anovulatory infertility.
Q. Why have I been prescribed Letfirst Tablet?
Letfirst Tablet is an aromatase inhibitor. It is generally prescribed to treat breast cancer in women who no longer have periods, either due to menopause or after surgery or chemotherapy.
Q. How does Letfirst Tablet work?
Letfirst Tablet is also known as an anti-estrogen drug. It is called so because it acts by reducing the production of estrogen in your body by blocking the enzyme aromatase, which is responsible for production of estrogen. Estrogen stimulates the production of certain types of breast cancer in your body. These cancers are called "estrogen-dependent cancers". Reducing the production of estrogen may prevent the cancer from growing.
Q. For how long should I take Letfirst Tablet?
If the breast tumor is in advanced stage or has spread to other parts of the body, it is recommended that you continue taking Letfirst Tablet till the tumor shows progression. In cases where Letfirst Tablet is given after tamoxifen (another anti-estrogen used for breast cancer) or surgery, it should be given for 5 years or until tumor comes back, whichever is first. It can also be given as a sequential treatment; 2 years of Letfirst Tablet followed by 3 years of tamoxifen.
Q. If I am taking irbesartan to control my blood pressure, can I take Letfirst Tablet?
Yes, you can take irbesartan and Letfirst Tablet together. However, be careful and keep a regular check on your blood pressure since Letfirst Tablet may increase your blood pressure. Consult your doctor in case you have problems controlling your blood pressure.
Q. Does Letfirst Tablet affect vision?
Although it is very uncommon but Letfirst Tablet may cause cataract. So, if you experience blurred vision or eye irritation, consult your doctor immediately.
Q. My friend who is taking Letfirst Tablet often sweats a lot. Is it because of Letfirst Tablet?
This could be a sign of hot flushes which is a very common side effect of Letfirst Tablet. It happens due to decreased estrogen levels. The frequency of hot flushes reduces once your body adjusts to Letfirst Tablet. However, in some people the flushes and sweats may continue during the treatment and stop a few months after the treatment finishes. You can consult your doctor who will provide you a remedy if it is very bothersome.
Q. What are the serious side effects of Letfirst Tablet?
The serious side effects do not occur in everyone and very few people experience them. The serious side effects of Letfirst Tablet include stroke, angina, heart attack, blood clotting, cataract, osteoporosis and severe skin reactions.
Q. Does Letfirst Tablet cause bone loss?
Letfirst Tablet may cause thinning or wasting of your bones (osteoporosis), which is due to the decrease in estrogen levels in your body. Your doctor may decide to measure your bone density (a way of monitoring for osteoporosis) before, during and after treatment.
Q. Can I take Letfirst Tablet for induction of ovulation in anovulatory infertility?
As per the Ministry of Health and Family Welfare, Letfirst Tablet is restricted for use in induction of ovulation in anovulatory infertility.

Content on this page was last updated on 03 November, 2025, by Dr. Rajeev Sharma (MBA, MBBS)