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Golbi 300 Tablet

Tablet
Rs.719for 1 strip(s) (15 tablets each)
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Composition FOR Golbi 300mg Tablet

Ursodeoxycholic Acid(300mg)

food interaction for Golbi Tablet

alcohol interaction for Golbi Tablet

pregnancy interaction for Golbi Tablet

lactation interaction for Golbi Tablet

food
alcohol
pregnancy
lactation
Golbi 300 Tablet should be taken with or after food.
None
CAUTION
It is not known whether it is safe to consume alcohol with Golbi 300 Tablet. Please consult your doctor.
CONSULT YOUR DOCTOR
The safety of Golbi 300 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
CONSULT YOUR DOCTOR
Information regarding the use of Golbi 300 Tablet during breastfeeding is not available. Please consult your doctor.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Golbi 300mg Tablet

Ursodeoxycholic Acid(300mg)

Golbi tablet uses

{med_name} is used in the treatment of gallbladder stones and primary biliary cirrhosis.

How golbi tablet works

Golbi 300 Tablet is a hepatoprotective medication. It works by reducing the amount of cholesterol in the blood and helps dissolve gallbladder stones that are composed mainly of cholesterol. It also improves liver enzymes, protects liver cells from injury caused due to toxic bile acids, and improves liver function.

Common side effects of golbi tablet

Abdominal pain, Diarrhea, Nausea, Rash, Hair loss, Cough, Sinus inflammation, Upper respiratory tract infection, Urinary tract infection, Allergy, Chest pain, Dyspepsia, Abdominal discomfort, Headache, Itching, Back pain, Fatigue, Flatulence, Vomiting, Joint pain, Joint inflammation, Muscle pain, Insomnia (difficulty in sleeping), Bronchitis (inflammation of the airways)

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Expert advice FOR Golbi Tablet

  • Take Ursodeoxycholic Acid after a meal with a glass of milk or water to help improve its absorption and reduce stomach upset.
  • Take Ursodeoxycholic Acid regularly at the same time each day, as it works gradually and may take time to show beneficial results.
  • Follow a healthy diet and exercise regularly, and avoid alcohol while taking Ursodeoxycholic Acid.
  • Avoid heavy or oily meals, as high-fat foods may worsen gallbladder or liver-related symptoms.
  • Diarrhea may occur as a side effect. Drink plenty of fluids, including oral rehydration solution (ORS), and inform your doctor if it persists or if you notice blood in your stools.
  • Your doctor may monitor liver function tests and bilirubin levels regularly, especially during the first few months of the treatment.
  • Seek medical advice promptly if you develop worsening jaundice, severe itching, dark urine, pale stools, persistent abdominal pain, or fever.
  • Do not stop taking Ursodeoxycholic Acid without consulting your doctor, as liver conditions often require monitored and continuous therapy.
  • Inform your doctor about all other medicines, herbal products, or supplements you are taking to avoid potential interactions.

Frequently asked questions FOR Golbi 300mg Tablet

Ursodeoxycholic Acid

Q. How should Golbi 300 Tablet be taken to ensure maximum absorption?
Golbi 300 Tablet should usually be taken with food or milk to help your body absorb it better and to reduce the chance of stomach upset. Taking it at the same time every day helps maintain a steady level of the medicine in your body. If you consume antacids that contain aluminum, they may interfere with how well Golbi 300 Tablet is absorbed. Taking it with a moderately high-fat meal (e.g., meals containing milk, curd, nuts, or oils) may further help in the absorption of ursodeoxycholic acid by promoting bile secretion.
Q. What are the side effects of Golbi 300 Tablet?
Golbi 300 Tablet is generally well tolerated. Common side effects include diarrhea (most frequent), nausea, and abdominal discomfort. These are usually mild and temporary. Rarely, it may alter liver enzyme levels, especially with long-term use, so your doctor may recommend periodic monitoring.
Q. What is Golbi 300 Tablet and what is it used for?
Golbi 300 Tablet contains ursodeoxycholic acid and is mainly used to dissolve certain cholesterol gallstones and to treat liver diseases such as primary biliary cholangitis. It works by lowering cholesterol levels in bile, improving bile flow, and protecting liver cells from damage. This can help reduce elevated liver enzyme levels and support overall liver function. It should only be used after proper evaluation and diagnosis by your doctor.
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Q. Does Golbi 300 Tablet cause weight gain?
Although uncommon, Golbi 300 Tablet may lead to weight gain, which has been reported in some patients with specific liver conditions, where bile flow was reduced. The likelihood varies depending on the underlying diseases and individual response. If you notice unexpected weight gain while taking Golbi 300 Tablet, please consult your doctor.
Q. What should be avoided while taking Golbi 300 Tablet?
While taking Golbi 300 Tablet, avoid certain medications, such as antacids, cholestyramine, and colestipol, as they may reduce its effectiveness. Hormonal medications that contain estrogen and drugs such as clofibrate may increase the risk of gallstones and interfere with the treatment. Alcohol should be limited or avoided because it can strain the liver and reduce the protective effects of Golbi 300 Tablet. Always inform your doctor about all medications, supplements, and your lifestyle habits.
Q. Can the body become resistant to Golbi 300 Tablet?
The body typically does not develop resistance to Golbi 300 Tablet, unlike with antibiotics. However, if gallstones become hardened with calcium and do not dissolve with Golbi 300 Tablet, or if bile flow does not improve and liver enzyme levels remain elevated, it may indicate progression of the underlying condition.
Q. Are there specific food interactions with Golbi 300 Tablet?
There are no strict food restrictions while taking Golbi 300 Tablet, but it is best to avoid very greasy or spicy foods, as they can trigger gallbladder discomfort and worsen symptoms. A balanced, high-fiber diet may support digestion and overall treatment effectiveness. Always follow any specific dietary recommendations your doctor provides.
Q. How does Golbi 300 Tablet dissolve gallstones?
Golbi 300 Tablet works by altering bile composition in the gallbladder, creating conditions that allow cholesterol gallstones to slowly dissolve back into liquid bile. This process is gradual and only works for stones primarily made of cholesterol. The gallbladder must still be functioning properly for treatment to be effective. Your doctor may recommend periodic ultrasounds to monitor the treatment progress.
Q. How long can I safely take Golbi 300 Tablet?
The duration of treatment with Golbi 300 Tablet depends on your medical condition and response to therapy. For fatty liver disease, it may be prescribed for a few months, while chronic conditions such as primary biliary cholangitis may require long-term use. When taken under medical supervision, Golbi 300 Tablet is generally safe for extended treatment. Regular blood tests and imaging studies may be needed to monitor your liver function and ensure ongoing safety and effectiveness.
Q. Can Golbi 300 Tablet affect your skin or hydration?
In rare cases, Golbi 300 Tablet may cause dry skin or a mild rash. Staying well hydrated supports overall health and liver function. Drinking adequate fluids and using a gentle moisturizer may help if mild dryness occurs. If you experience a severe skin reaction, stop taking Golbi 300 Tablet and contact your doctor immediately.
Q. What warning signs should you watch out for?
You should seek immediate medical attention if you develop severe right-sided abdominal pain, intense yellowing of the skin or eyes (jaundice), or severe and persistent diarrhea. These symptoms may indicate a blocked bile duct or a rare, serious reaction. Any unusual or worsening symptoms should be reported to your doctor promptly.

Content on this page was last updated on 07 April, 2026, by Dr. Sachin Gupta (MD Pharmacology, MBBS)