Glynase-MF Tablet

Tablet
Rs.19for 1 strip(s) (10 tablets each)
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Composition FOR Glynase-MF

Glipizide(5mg),Metformin(500mg)

food interaction for Glynase-MF

alcohol interaction for Glynase-MF

pregnancy interaction for Glynase-MF

lactation interaction for Glynase-MF

food
alcohol
pregnancy
lactation
Glynase-MF Tablet is to be taken with food.
Glynase-MF Tablet may cause stomach upset if taken on empty stomach
None
CAUTION
It is unsafe to consume alcohol with Glynase-MF Tablet.
UNSAFE
Glynase-MF Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Glynase-MF Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Glynase-MF

Glipizide(5mg)

Uses

Glipizide is used in the treatment of type 2 diabetes mellitus. It is used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

How it works

Glipizide is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.

Common side effects

Dizziness, Diarrhea, Nervousness, Tremors, Hypoglycemia (low blood glucose level), Flatulence, Headache, Nausea, Vomiting, Weight gain, Abdominal discomfort, Abnormal sensation, Vasculitis, Hypersensitivity, Abnormal liver function, Increased creatinine level in blood, Increased blood urea, Rash, Itching, Bullous dermatoses (skin disease characterized by presence of blisters), Liver failure
Metformin(500mg)

Uses

Metformin is used in the treatment of type 2 diabetes mellitus and polycystic ovarian syndrome (PCOS).

How it works

Metformin is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from the intestines, and increasing the body's sensitivity to insulin.

Common side effects

Diarrhea, Headache, Vomiting, Nausea, Flatulence, Indigestion, Vitamin B12 deficiency, Abdominal discomfort, Hepatitis (viral infection of liver), Drug eruptions, Lactic acidosis, Hypoglycemia (low blood glucose level)

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Expert advice FOR Glynase-MF

  • Take it shortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals.
  • Be careful while driving or operating machinery until you know how Glipizide affects you.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
  • Glipizide helps decrease high blood sugar level and avoid long-term complications of diabetes.
  • Take it shortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals.
  • Exercise regularly, eat a healthy diet and take your other diabetes medicines (if prescribed) alongside.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.
  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • Be careful while driving or operating machinery until you know how Glipizide affects you.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Frequently asked questions FOR Glynase-MF

Glipizide

Q. What is the best time to take Glipizide?
Take Glipizide before meals or exactly as instructed by your doctor. There is evidence stating that Glipizide works best at controlling post meal high blood sugar levels when taken 30 minutes before breakfast. So, if you are supposed to take it once daily, take it in the morning before breakfast with a glass of water.
Q. Is Glipizide the same as metformin?
No, Glipizide is not the same as metformin. Although both these oral medicines are used in the treatment of type 2 diabetes, the way they work to reduce the sugar levels are different. While Glipizide acts by increasing the secretion of insulin by the pancreas, metformin acts by improving the functioning and effectiveness of the insulin already available in the body.
Q. Is Glipizide bad for kidneys?
No, Glipizide is not harmful if your kidney function is normal. Any previous case of kidney problem should be informed to the doctor, so that the use of Glipizide can be assessed. This is done in order to analyze whether Glipizide can be given or not because it is principally excreted by the kidney. If you have kidney problems you will be started at a lower dose.
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Q. Does Glipizide make you sleepy?
Glipizide itself does not cause sleepiness. However, it may cause hypoglycemia (low blood sugar) when used with other anti-diabetes medicine. Because of this you may feel sleepy or have problems in sleeping.
Q. Can I take Glipizide with insulin?
Glipizide, when used with insulin, can help to control high blood sugar levels. Taking them together can help to lower the dose of insulin but there could also be an increased risk of hypoglycemia. Dose of these medicines may need to be adjusted along with regular blood sugar level monitoring.
Q. Does Glipizide cause weight gain?
Yes, Glipizide can cause weight gain. It is advisable to closely monitor your diet and do regular exercise while taking this medicine. Avoid skipping your meal as it can cause very low blood sugar levels and you may end up snacking or taking a lot of sugars.
Q. Is Glipizide a Thiazolidinedione?
No, Glipizide is not a Thiazolidinedione, it is a sulfonylurea. However, both are antidiabetic medicines but belong to a different group of medicines.
Q. Who should not take Glipizide?
Glipizide should be avoided by patients who are allergic to it, have severe kidney or liver disease, have G6PD-deficiency (an inherited condition affecting red blood cells), or are due to have surgery. Along with that, patients who are trying to get pregnant, are pregnant, or breastfeeding, or have insulin-dependent diabetes (type 1 diabetes mellitus) should also avoid taking Glipizide.
Q. What can happen if I take more than the recommended dose of Glipizide?
Overdose of Glipizide may significantly decrease your blood sugar levels (hypoglycemia). If you have taken an excess dose then you should instantly consume enough sugar (e.g., a small bar of sugar cubes, sweet juice or sweetened tea) and inform a doctor immediately. Severe cases of hypoglycemia accompanied by loss of consciousness and coma are cases of medical emergency requiring immediate medical attention.
Q. Can I skip Glipizide for a few days?
No, Glipizide should not be skipped, as it can make your diabetes worse. If, you miss the dose by mistake, take it as soon as you remember.

Metformin

Q. What does Metformin do exactly?
People with type 2 diabetes are not able to make enough insulin or respond normally to the insulin made by their bodies. When this happens, the concentration of sugar/glucose increases in the blood. Metformin acts in several ways to reduce the increased levels of sugar in blood. Metformin decreases glucose production from the liver and decreases absorption of glucose from the intestine after taking food while improving the sensitivity of the body organs and muscles towards insulin. This helps improve the uptake of glucose from the blood. It also helps your body to respond better to the insulin it makes naturally.
Q. Does Metformin cause weight loss?
Yes, Metformin has been shown to cause weight loss in people who are overweight or obese. It may also cause a modest loss in weight in those overweight and obese individuals who are at risk for diabetes. In addition, patients who are sensitive or resistant to insulin may also show weight loss. But, do not start taking this medicine for weight loss on your own. Consult your doctor for the same.
Q. What are the benefits of taking Metformin?
Metformin is one of the first medicines that is given to patients with high blood sugar levels. It helps control blood sugar levels. It promotes the body’s response to the insulin made by the pancreas, decreases the amount of sugar made by the liver and decreases the amount of sugar absorbed by the intestines. Unlike other oral antidiabetic medicines, Metformin when taken alone, rarely causes low blood sugar as it prevents the pancreas from secreting more insulin. In addition to being a great medicine to lower blood sugar levels, it also helps in controlling weight gain.
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Q. Can Metformin make you sleepy?
Metformin usually does not cause sleepiness and is well tolerated. However, the use of Metformin may rarely cause sleep disorders and insomnia. Sleepiness may be due to a very serious side effect called lactic acidosis, which particularly occurs if your kidneys are not working properly. Contact your doctor if you feel sleepy or tired while taking Metformin.
Q. How to take Metformin?
Take Metformin with or after a meal. Do not crush or chew the tablets and swallow it with a glass of water. If your doctor has prescribed one tablet a day, prefer taking it in the morning with breakfast. If you have been prescribed two tablets a day, then take one in the morning and other in the evening with dinner. In case of three doses a day, apart from morning and evening, you can take it with lunch. Taking Metformin with meals will reduce its digestive problems like indigestion, nausea, vomiting, diarrhea, stomach ache and loss of appetite.

Content on this page was last updated on 11 November, 2024, by Dr. Varun Gupta (MD Pharmacology)