Glyboral 5mg Tablet

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Composition FOR Glyboral 5mg Tablet

Glibenclamide(5mg)

food interaction for Glyboral Tablet

alcohol interaction for Glyboral Tablet

pregnancy interaction for Glyboral Tablet

lactation interaction for Glyboral Tablet

food
alcohol
pregnancy
lactation
Glyboral 5mg Tablet is to be taken with food.
None
CAUTION
It is unsafe to consume alcohol with Glyboral 5mg Tablet.
UNSAFE
Glyboral 5mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Glyboral 5mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Monitor the breastfed baby’s blood sugar during treatment with Glyboral 5mg Tablet
SAFE IF PRESCRIBED

SALT INFORMATION FOR Glyboral 5mg Tablet

Glibenclamide(5mg)

Glyboral tablet uses

{med_name} is used in the treatment of type 2 diabetes mellitus. It is used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

How glyboral tablet works

Glyboral 5mg Tablet is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.

Common side effects of glyboral tablet

Hypoglycemia (low blood glucose level), Nausea, Headache, Dizziness

SUBSTITUTES FOR Glyboral Tablet

45 Substitutes
45 Substitutes
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  • Euglucon Tablet
    (10 tablets in strip)
    Rs. 1.10/Tablet
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    pay 108% more per Tablet
  • Glinil Tablet
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    Rs. 0.89/Tablet
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    Rs. 10.31
    pay 68% more per Tablet

Expert advice FOR Glyboral Tablet

  • Take it shortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals.
  • Be careful while driving or operating machinery until you know how Glibenclamide affects you.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
  • Glibenclamide helps decrease high blood sugar level and avoid long-term complications of diabetes.
  • Take it shortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals.
  • Exercise regularly, eat a healthy diet and take your other diabetes medicines (if prescribed) alongside.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.
  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • Be careful while driving or operating machinery until you know how Glibenclamide affects you.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Frequently asked questions FOR Glyboral 5mg Tablet

Glibenclamide

Q. Is Glyboral 5mg Tablet the same as Glipizide?
No, Glyboral 5mg Tablet and Glipizide are different medicines. However, they belong to the same class of medicines called sulfonylureas and are used to treat type 2 diabetes mellitus in adults.
Q. Does Glyboral 5mg Tablet play any role in the treatment of polycystic ovarian syndrome (PCOS)?
No, Glyboral 5mg Tablet is not known to have any role in the treatment of polycystic ovarian syndrome (PCOS). Also, there is no clinical evidence available regarding the same.
Q. Why should Glyboral 5mg Tablet be used cautiously in elderly patients?
Glyboral 5mg Tablet should be used with extra caution in elderly patients because they are at high risk of getting low blood sugar (hypoglycemic event).
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Q. Is Glyboral 5mg Tablet useful in the management of prediabetes?
Glyboral 5mg Tablet is not used for the management of prediabetes, a condition with blood glucose levels higher than normal but not high enough to label you as diabetic. There are clinical studies available, but the evidence is not strong enough for its use in prediabetes.
Q. How is Glyboral 5mg Tablet different from Teneligliptin?
Both Glyboral 5mg Tablet and Teneligliptin are antidiabetic medicines and control blood sugar levels effectively. However, they work in different ways and may show different kinds of side effects. Glyboral 5mg Tablet commonly causes hypoglycemia and weight gain while Teneligliptin causes headache and nasopharyngitis. Teneligliptin causes hypoglycemia when used along with insulins or sulfonylureas and does not cause weight gain.
Q. Can I skip Glyboral 5mg Tablet for a few days?
No, Glyboral 5mg Tablet should not be skipped as it can make your diabetes worse. If you miss the dose by mistake, take it as soon as you remember.
Q. Can I take Glyboral 5mg Tablet if I have a sulfa allergy?
Use of Glyboral 5mg Tablet should be avoided if you are allergic (hypersensitive) to sulfonylureas or sulfonamides or any of the other ingredients of this medicine.
Q. Does Glyboral 5mg Tablet cause weight gain?
Yes, Glyboral 5mg Tablet can cause weight gain. It is advisable to closely monitor your diet and exercise regularly while taking this medicine. Avoid skipping your meals as it can cause very low blood sugar levels and you may end up snacking or taking a lot of sugars.
Q. Is there any benefit of taking Glyboral 5mg Tablet with insulin?
Glyboral 5mg Tablet, when used with insulin, can help to control high blood sugar levels. Taking them together can help to lower the dose of insulin but there could also be an increased risk of hypoglycemia (low blood sugar levels). The dose of these medicines may need to be adjusted along with regular blood sugar level monitoring. Please consult your doctor if you have any doubts and follow your doctor's instructions carefully to get maximum benefit of Glyboral 5mg Tablet.
Q. Is it safe to take Glyboral 5mg Tablet with Liraglutide?
Yes, Glyboral 5mg Tablet and Liraglutide can be taken together, as they can help in better control of blood sugar levels. However, the risk of low blood sugar levels (hypoglycemia) can increase. Consult your doctor as a dose adjustment of the two may be needed.
Q. Is Glyboral 5mg Tablet a Thiazolidinedione?
No, Glyboral 5mg Tablet is not a Thiazolidinedione, it is a sulfonylurea. However, both are antidiabetic medicines but belong to a different group of medicines.
Q. Is Glyboral 5mg Tablet useful in the management of gestational diabetes?
The use of insulin is advised during pregnancy to control the blood glucose levels. Insulin injections are the standard medication for gestational diabetes. Glyboral 5mg Tablet may be advised as an alternative or in addition to insulin for the management of gestational diabetes. However, do not start taking Glyboral 5mg Tablet until prescribed by the doctor.
Q. Does Glyboral 5mg Tablet cause hair loss?
No, hair loss is not seen with the use of Glyboral 5mg Tablet. However, diabetes can lead to hair loss. Talk to your doctor if you have excessive hair loss as it could be due to some other underlying condition or it could be a sign of your diabetes getting worsened.
Q. Is it safe to take Glyboral 5mg Tablet with pioglitazone?
Yes, it is safe to take Glyboral 5mg Tablet with Pioglitazone in patients with diabetes mellitus. Together these two medicines can control your blood sugar levels, lower plasma lipid levels and improve blood pressure. However, the risk of very low blood sugar levels can increase and the dose of these medicines may need to be adjusted.

Content on this page was last updated on 23 September, 2025, by Dr. Sachin Gupta (MD Pharmacology, MBBS)