Q. What is the difference between Dolonip 20mg Injection and ketoprofen?
Both Dolonip 20mg Injection and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Dolonip 20mg Injection. Ketoprofen gel also showed excellent tolerability.
Q. What is the difference between Dolonip 20mg Injection and tramadol?
Dolonip 20mg Injection is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
Q. What is the difference between Dolonip 20mg Injection and nimesulide?
Both Dolonip 20mg Injection and nimesulide are pain killers. However, Dolonip 20mg Injection is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
Q. Can Dolonip 20mg Injection be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Dolonip 20mg Injection or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Dolonip 20mg Injection.
Q. Are Dolonip 20mg Injection and aspirin same?
No. Dolonip 20mg Injection and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
Q. Can Dolonip 20mg Injection be used along with dexamethasone?
No. Dolonip 20mg Injection should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
Q. Can Dolonip 20mg Injection be used with methocarbamol?
Yes. Methocarbamol can be used with Dolonip 20mg Injection as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Can Dolonip 20mg Injection be used along with paracetamol?
Yes. Paracetamol can be used with Dolonip 20mg Injection as no serious side effects are known. Inform your doctor before starting any of the medication.
Q. Is Dolonip 20mg Injection a NSAID?
Yes. Dolonip 20mg Injection is a non-steroidal anti-inflammatory drug (NSAID).
Q. Is Dolonip 20mg Injection a sulfa drug?
Dolonip 20mg Injection is a sulphur containing compound. Dolonip 20mg Injection can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
Q. Is Dolonip 20mg Injection a blood thinner?
No. Dolonip 20mg Injection is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
Q. Is Dolonip 20mg Injection a muscle relaxant?
No. Dolonip 20mg Injection is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
Q. Is Dolonip 20mg Injection a narcotic?
No. Dolonip 20mg Injection is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
Q. Can Dolonip 20mg Injection be used in hypertension?
No. Dolonip 20mg Injection is not a medication to control hypertension. It is important to note that Dolonip 20mg Injection decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Dolonip 20mg Injection.
Q. Can Dolonip 20mg Injection be used along with Losartan?
No. Dolonip 20mg Injection should not be combined with Losartan. It is important to note that Dolonip 20mg Injection decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Dolonip 20mg Injection.
Q. Can Dolonip 20mg Injection be used with Lisinopril?
No. Dolonip 20mg Injection should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Dolonip 20mg Injection.
Q. Can Dolonip 20mg Injection be used with calcium channel blocker?
Yes. Dolonip 20mg Injection can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
Q. Can Dolonip 20mg Injection be used with Tizanidine?
Yes, Dolonip 20mg Injection can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
Q. Why is beta cyclodextrin added to Dolonip 20mg Injection?
Yes. Dolonip 20mg Injection can be combined with beta-cyclodextrin. Research has shown that combining Dolonip 20mg Injection with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
Q. Are there any alternatives of Dolonip 20mg Injection?
Yes. There are alternatives to Dolonip 20mg Injection. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
Q. What are the contraindications for Dolonip 20mg Injection?
Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
Q. Can Dolonip 20mg Injection be used in the treatment of allergy?
No. Dolonip 20mg Injection is not a drug to treat allergy. It is a pain killer.
Q. How long does Dolonip 20mg Injection work?
Dolonip 20mg Injection is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
Q. Can you get high by using Dolonip 20mg Injection?
No. Dolonip 20mg Injection is not known to cause high. It is a non-narcotic painkiller.
Q. Can Dolonip 20mg Injection be used to treat menstrual cramp?
Dolonip 20mg Injection is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
Q. Can I use Dolonip 20mg Injection for a migraine?
Dolonip 20mg Injection is not approved for the treatment of migraine. Research studies have shown that Dolonip 20mg Injection is effective in significantly decreasing the pain associated with migraine without aura.
Q. Is Dolonip 20mg Injection effective in back pain management?
Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Dolonip 20mg Injection as the cause of back pain can be different for different person.
Q. Is Dolonip 20mg Injection affective in gout management?
Yes. Dolonip 20mg Injection can be given for the treatment of acute gout. Research studies have shown Dolonip 20mg Injection to be highly effective in the treatment of acute gout.
Q. Can you donate blood when on the medication with Dolonip 20mg Injection?
Yes. You can donate blood when on Dolonip 20mg Injection. Do inform your doctor before donating blood.
Q. Can I use Dolonip 20mg Injection if I am a diabetic?
Dolonip 20mg Injection in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Dolonip 20mg Injection so taking piroxicam can lead to increased risk of renal failure by many folds.
Q. Can I use Dolonip 20mg Injection if I have a deranged renal function?
No. Dolonip 20mg Injection should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
Q. Can Dolonip 20mg Injection lead to skin reactions?
Yes. Dolonip 20mg Injection is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
Q. Can I use Dolonip 20mg Injection if I am pregnant?
No. Dolonip 20mg Injection should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
Q. Can I use Dolonip 20mg Injection if I have peptic ulcer disease?
No. Dolonip 20mg Injection is contraindicated in cases of active peptic ulcer disease. Dolonip 20mg Injection is known to cause gastric ulceration and bleeding.
Q. Can I use Dolonip 20mg Injection if I have asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. Can Dolonip 20mg Injection lead to difficulty in conception?
Yes. Dolonip 20mg Injection can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Can Dolonip 20mg Injection be used with diuretics?
No. Dolonip 20mg Injection should not be used with diuretics. Dolonip 20mg Injection reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Can Dolonip 20mg Injection be used with lithium?
No. Dolonip 20mg Injection should not be used with lithium. Dolonip 20mg Injection leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
Q. Can Dolonip 20mg Injection be used with warfarin?
No. Dolonip 20mg Injection should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
Q. What increases the chances of getting a gastric ulcer when I am already taking Dolonip 20mg Injection?
The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Dolonip 20mg Injection?
Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
Q. What are the serious side effects of Dolonip 20mg Injection?
GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.
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