D Penem S 1000mg/500mg Injection

Injection
Rs.2666for 1 vial(s) (1 Injection each)
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Composition FOR D Penem S

Meropenem(1000mg),Sulbactam(500mg)

food interaction for D Penem S

alcohol interaction for D Penem S

pregnancy interaction for D Penem S

lactation interaction for D Penem S

food
alcohol
pregnancy
lactation
No interaction found/established
Caution is advised when consuming alcohol with D Penem S 1000mg/500mg Injection. Please consult your doctor.
CAUTION
D Penem S 1000mg/500mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
D Penem S 1000mg/500mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
SAFE IF PRESCRIBED

SALT INFORMATION FOR D Penem S

Meropenem(1000mg)

Uses

Meropenem is used in severe bacterial infections. It is used in infections of various body parts like skin and soft tissues, urinary tract, blood, brain and lungs (pneumonia).

How it works

Meropenem is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

Common side effects

Rash, Headache, Vomiting, Nausea, Itching, Diarrhea, Injection site inflammation, Anemia (low number of red blood cells), Sepsis, Constipation, Apnea (absence of breathing), Shock, Thrombophlebitis, Injection site reactions (pain, swelling, redness), Abdominal pain, Gastrointestinal bleeding, Dark colored stool, Nosebleeds, Intrabdominal bleeding, Chest pain, Heart failure, Fast heart rate, High blood pressure, Hypotension (low blood pressure), Oral fungal infection, Decreased appetite, Cholestatic jaundice, Jaundice, Peripheral edema, Insomnia (difficulty in sleeping), Agitation, Delirium (acute confusional state), Respiratory disorder, Red spots or bumps, Renal failure, Vaginal yeast infection, Urinary incontinence, Inflammation of vein, Hypersensitivity, Cutaneous reactions, Clostridium difficile associated diarrhea, Low blood platelets
Sulbactam(500mg)

Uses

Sulbactam is used in the treatment of severe bacterial infections. It treats severe bacterial infections (most commonly pneumonia, bacteremia and skin and skin structure infections) caused by the pathogen Acinetobacter baumanii.

How it works

Sulbactam is a beta-lactamase inhibitor. It works by blocking an enzyme called beta lactamase produced by bacteria to inactivate antibiotics. Sulbactam is frequently combined with beta-lactam antibiotics, such as ampicillin, cefoperazone, meropenem. As a single medicine, it treats infection caused by a type of bacterium called Acinetobacter baumanii. This activity is mediated by its interaction with certain proteins.

Common side effects

Diarrhea, Injection site pain

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Expert advice FOR D Penem S

  • Meropenem is an antibiotic that's usually only given in the hospital for serious infections.
  • It is given by a drip into a vein (intravenous infusion) over 20 to 60 minutes.
  • Inform your doctor if you are allergic to penicillin or if you are taking any seizure medication before starting treatment with this medication.
  • Diarrhea may occur as a side effect. Inform your doctor if you develop severe stomach pain or if you find blood in your stools.
  • Your doctor may monitor your kidney function and blood count while you are having treatment with this medication.

Frequently asked questions FOR D Penem S

Meropenem

Q. My friend has a history of epilepsy and she was on valproic acid while receiving treatment with Meropenem, still, she had an episode of seizure. Why?
Any previous history with any other medication should be informed to the doctor before starting your treatment with Meropenem. Medicines like Meropenem can interfere with valproic acid which is used for the treatment of epilepsy, making it less effective. So, the reason for the recent episode of seizure could be the result of such drug interaction. Generally, in cases like these, the doctor prescribes a different medicine.
Q. Even though Meropenem is used for skin infections, can it cause any skin-related problems?
Serious skin reactions are rare, but some have been reported with the use of Meropenem. Therefore, before starting the treatment inform your doctor if you are allergic to any medicine or antibiotic. Serious skin reactions are a type of allergic reaction. But, if not properly managed then they can endanger life. So, if you notice any rash along with fever or peeling of the skin, discontinue the medication and inform your doctor.
Q. Is Meropenem a strong antibiotic? Which infections does it treat?
Meropenem is a broad-spectrum antibiotic which means it can treat a variety of bacterial infections. It is used to treat infections affecting the lungs (pneumonia) and complicated infections of the urinary tract, abdomen, and skin and soft tissue infections. Along with that, it is also helpful in treating bacterial infection of the membranes that surround the brain and spinal cord (meningitis) and infections that occur during or after delivery.
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Q. Is Meropenem effective against bacteria only? Can it be used for any type of bacterial infection?
Yes, Meropenem is effective only against bacteria. It is not effective against virus or fungal infections. Meropenem is effective against some bacteria which include Staphylococcus aureus, Streptococcus pneumoniae, S. pyogenes, S. viridans group, etc. Therefore, its use against any other type of bacteria should be avoided.
Q. My cousin was receiving Meropenem for severe skin infection, but the medicine was stopped when she had a fit. Was the fit due to Meropenem?
There are reports which suggest the occurrence of seizures or fits with the use of Meropenem. However, fits are more likely to occur in patients with a history of seizures or a brain lesion (wound, ulcer, abscess or tumor) or patients having bacterial meningitis or compromised kidney function. Consult your doctor to understand the exact reason.
Q. For how long will I need to take Meropenem?
The length of the treatment will be decided by your doctor. The doctor will decide the dose depending on your general health, the type of infection you have, and how well you respond to Meropenem. Consult your doctor if you are not sure.
Q. What if Meropenem does not suit me?
It is common to have minor side effects such as nausea, vomiting, diarrhea, and headache with the use of Meropenem. However, these symptoms generally settle down with continued medication as the body adapts to the medicine. If the side effects bother you, inform your doctor. The doctor will suggest an alternative medicine if required. Serious side effects with Meropenem are very rare. In case you develop serious side effects, seek immediate medical advice.
Q. Does it matter if I miss or stop Meropenem?
You mustn't stop the treatment without consulting your doctor. Stopping the treatment may bring back the infection or you may develop resistance to Meropenem. Similar results may be seen if you skip any dose or are forgetful in taking the suggested doses. Therefore, it is recommended that you do not miss doses. If you do, take the missed dose as soon as you can and take the next dose as planned so that you stick to the same overall daily dose.

Sulbactam

Q. Why is Sulbactam added to other antibiotics?
Sulbactam added to other antibiotics like ampicillin, cefoperazone, etc., because Sulbactam contains Sulbactam, a beta-lactamase inhibitor, which reduces resistance and enhances the activity of other antibiotics like ampicillin, cefoperazone, etc., against the bacteria.
Q. Who should not take Sulbactam?
Sulbactam should not be taken by an individual if he/she had an allergic reaction to ampicillin, sulbactam, or any penicillin antibiotic (such as penicillins or cephalosporins), or if he/she has a history of liver problems caused by ampicillin/sulbactam.
Q. What should I discuss with my doctor before receiving Sulbactam?
Before taking Sulbactam, you should tell your doctor if you have ever had an allergic reaction to Sulbactam or any similar medicine. Inform the doctor if you have any type of allergy, asthma or breathing problems, heart disease or kidney disease. Let your doctor know about all the medicines that you may be taking as they may affect or be affected by Sulbactam. Pregnant or breastfeeding mothers should also seek their doctor’s advice before taking Sulbactam.
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Q. Can I use a discolored solution of Sulbactam?
No. You should not use Sulbactam if the medicine has changed colors or has particles in it. The discolored solution may be contaminated and may not be as effective as it is expected to be. Also, it may cause additional side effects. So, it is better, that you discard the solution and go for another vial.
Q. I feel better now. Can I stop taking Sulbactam?
No. Make sure to receive all doses your doctor has prescribed, even if you feel better. This is because your symptoms may have improved but chances are that the infection is still present in your body. Skipping doses can increase the risk of developing an infection that is resistant to medication. So, continue taking Sulbactam as prescribed. After you have finished all the doses, your doctor may advise you on some tests to make sure your infection has completely cleared up.
Q. Does Sulbactam treat the flu?
No. Sulbactam does not treat a viral infection such as the flu or a common cold.

Content on this page was last updated on 29 November, 2023, by Dr. Varun Gupta (MD Pharmacology)