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Barbitoin 30 mg/100 mg Tablet

Medopharm
Tablet
As per Ministry of Health and Family Welfare
BANNED FOR SALE
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Composition FOR Barbitoin

Phenobarbitone(30mg),Phenytoin(100mg)

food interaction for Barbitoin

alcohol interaction for Barbitoin

pregnancy interaction for Barbitoin

lactation interaction for Barbitoin

food
alcohol
pregnancy
lactation
Barbitoin 30 mg/100 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
None
CAUTION
It is unsafe to consume alcohol with Barbitoin 30 mg/100 mg Tablet.
UNSAFE
Barbitoin 30 mg/100 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
Barbitoin 30 mg/100 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Baby should be monitored for excessive sleepiness and weight gain.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Barbitoin

Phenobarbitone(30mg)

Uses

Phenobarbitone is used in epilepsy/seizures.

How it works

Phenobarbitone controls seizures or fits by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Common side effects

Nausea, Headache, Excitement, Hangover, Vomiting, Vertigo, Softening of bones, Sleepiness, Muscle pain, Neuralgia, Joint inflammation, Lethargy, Restlessness, Respiratory depression, Hypersensitivity
Phenytoin(100mg)

Uses

Phenytoin is used in the treatment of epilepsy/seizures.

How it works

Phenytoin is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Common side effects

Dizziness, Insomnia (difficulty in sleeping), Vertigo, Nystagmus (involuntary eye movement), Peripheral neuropathy (tingling and numbness of feet and hand), Skin rash, Softening of bones, Increased glucose level in blood, Megaloblastic anemia, Gingival hyperplasia, Excessive hair growth on face, Hypotension (low blood pressure), Abnormality of voluntary movements, Arrhythmia (irregular heartbeats), Encephalopathy, Psychosis, Hyperkinesia, Hypersensitivity, Stevens-Johnson syndrome, Cardiovascular collapse, Liver failure, Blood circulation disorder, Lymphatic system abnormalities

SUBSTITUTES FOR Barbitoin

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Expert advice FOR Barbitoin

  • Phenobarbitone helps in treatment and prevention of seizures.
  • It may be habit-forming with long-term use.
  • Talk with your doctor if it stops working well. Do not take more than prescribed.
  • It may make you very sleepy. Don't drive or do anything that requires mental focus until you know how it affects you.
  • Inform your doctor if you notice pain in your joints or if you have a history of bone disease.
  • Get regular blood tests done to monitor the amount of medication in your body.
  • Talk to your doctor immediately if you notice skin rash accompanied with fever.
  • Do not stop taking the medication suddenly without talking to your doctor.

Frequently asked questions FOR Barbitoin

Phenobarbitone

Q. What is Phenobarbitone used for?
Phenobarbitone is prescribed to control seizures or fits. Phenobarbitone belongs to barbiturate group of medicines. In exceptional circumstances, it is also used to treat seizures that sometimes accompany a high fever in children.
Q. What if I forget to take Phenobarbitone?
If you forget to take a dose, take it as soon as you remember. However, if it is time for the next dose, skip the forgotten dose and take the next dose. Do not double the dose to make up for the forgotten dose.
Q. Can Phenobarbitone cause addiction?
Yes, Phenobarbitone may cause addiction in patients with a history of alcoholism and drug abuse if they take it for a prolonged time. Therefore, Phenobarbitone should be avoided in such patients.
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Q. What are the long-term side effects of Phenobarbitone?
Long-term use of phenobarbital can lead to changes in the soft tissues of the body. Symptoms include pain in the joints or thickening in areas such as the palm or the bottom of the foot. If you notice any changes of this kind, tell the doctor.
Q. Can I stop taking Phenobarbitone once my seizures get controlled?
No, you should not stop taking Phenobarbitone without consulting your doctor. Sudden withdrawal can cause sleeplessness, anxiety, tremor, dizziness, feeling sick, fits and delirium. The dose of Phenobarbitone should be reduced gradually.
Q. What will happen if I accidentally take more than the recommended dose of Phenobarbitone?
Swallowing more than the recommended doses may cause drowsiness, speech problems, jerky movements, jerky eye movements, loss of inhibition, reduced reflex response, low body temperature, low blood pressure and breathing problems. Contact your nearest hospital emergency services or your doctor immediately.
Q. What are the effects of Phenobarbitone in children?
Phenobarbitone is useful in treating many kinds of seizures in children. It is often considered as the first choice to treat certain kinds of seizures in newborns. The child taking Phenobarbitone treatment may develop problems with behavior and learning. Side effects are much more likely to be troublesome if high doses are given or if too high a dose is given at the beginning of the treatment. It may be necessary to increase the dose very slowly over several months.
Q. Can I take folic acid with Phenobarbitone?
Phenobarbitone causes folic acid deficiency which is responsible for certain types of anemia (megaloblastic anemia) in some patients. But if you take folic acid, then it may decrease the levels of Phenobarbitone in your body. This may lead to seizures. Therefore, folic acid should be avoided.
Q. Can Phenobarbitone cause withdrawal symptoms?
Yes, suddenly stopping Phenobarbitone can cause withdrawal symptoms which include sleeplessness, anxiety, tremor, dizziness, nausea, fits, and delirium.
Q. Are there any tests available which check the levels of Phenobarbitone in the blood?
Yes, laboratory tests are available. If you feel excessively sleepy and experience tremor or balance issues or double vision, inform your doctor and get the levels checked.
Q. For how long do I need to take Phenobarbitone?
You should take Phenobarbitone for the duration advised by your doctor. This drug has a habit-forming effect, therefore, its long-term use is not recommended.

Phenytoin

Q. For how long does Phenytoin stay in your system?
On an average, Phenytoin may stay in your system for 5-6 days. This duration varies from person to person. In some cases, it may stay for about 9-10 days.
Q. What happens if I stop taking Phenytoin?
Suddenly stopping Phenytoin may cause non-stop seizures (called status epilepticus), which can endanger life. Do not stop taking the medicine without consulting your doctor. If required, your doctor will slowly reduce the dose before stopping it completely.
Q. What are the symptoms that occur if I take more than the recommended dose of Phenytoin? Can I die from Phenytoin overdose?
Overdose of Phenytoin may cause jerky movements of the eyes (nystagmus), unclear speech, loss of balance, tremor, muscle stiffness or weakness, nausea, vomiting, lightheadedness, fainting, blurred vision, slow and shallow breathing and even coma. Phenytoin overdose can cause very low blood pressure and respiratory problems. As a result of this, the patient can even die.
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Q. Who should avoid taking Phenytoin?
You should not take Phenytoin if you have liver disease, especially if you have a history of developing a liver problem due to Phenytoin. Also, patients taking Delavirdine (a medicine used in the treatment of HIV infection) should not take Phenytoin. Phenytoin may reduce the effectiveness of Delavirdine on HIV and the virus may also become resistant to Delavirdine. It is advised that you inform your doctor if you have any existing heart disorder before you receive Phenytoin.
Q. Can I take Phenytoin with ibuprofen?
Phenytoin can be taken with ibuprofen. No drug-drug interactions have been reported between the two. However, interactions can occur. Please consult your doctor before taking the two medicines together.
Q. What are the effects of Phenytoin on children?
The most common side effects related to Phenytoin in children are jerky movements of the eyes (nystagmus) and overgrowth of the gums. In some children, Phenytoin causes problems with thinking or behavior, mood change, slow or clumsy movements, or a loss of energy. Other side effects from high doses include unsteadiness in the feet and hands, sleepiness, and vomiting. These may be avoidable if the dose is increased slowly. These side effects quickly disappear when the dose is reduced.
Q. Does Phenytoin cause weight gain?
Phenytoin has not been reported to cause weight gain. However, weight loss can occur with longer term use of a higher dose of Phenytoin. Please consult your doctor if you experience weight gain after taking Phenytoin.
Q. Does Phenytoin make you sleepy?
Phenytoin can make you feel sleepy (sedation, somnolence, and drowsiness). Please consult your doctor if you feel very sleepy after taking Phenytoin, especially during the first few weeks of treatment or following a dose increase. Talk to your doctor as you may be advised not to drive or use machines until it is established that your ability to perform such activities is not affected.
Q. Does Phenytoin affect birth control?
Phenytoin does affect birth control. Phenytoin can decrease the effect of oral contraceptives (birth control pills) which can make the contraceptive (birth control) effect unreliable. Please talk to your doctor if you are asked to take the two medicines together as you may need to use extra protection for birth control.

Content on this page was last updated on 21 December, 2023, by Dr. Varun Gupta (MD Pharmacology)