Ampine RL 5 mg/2.5 mg Tablet

Tablet
Rs.37.70for 1 strip(s) (10 tablets each)
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Composition FOR Ampine RL

Amlodipine(5mg),Ramipril(2.5mg)

food interaction for Ampine RL

alcohol interaction for Ampine RL

pregnancy interaction for Ampine RL

lactation interaction for Ampine RL

food
alcohol
pregnancy
lactation
Ampine RL 5 mg/2.5 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
None
CAUTION
It is unsafe to consume alcohol with Ampine RL 5 mg/2.5 mg Tablet.
UNSAFE
Ampine RL 5 mg/2.5 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
Ampine RL 5 mg/2.5 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Ampine RL

Amlodipine(5mg)

Uses

Amlodipine is used in the treatment of Hypertension (high blood pressure) and Angina (heart-related chest pain).

How it works

Amlodipine is a calcium channel blocker. In high blood pressure, it normalizes the blood pressure by relaxing the blood vessels to reduce the pressure on them, thereby improving the blood flow in the body. The enhanced blood flow in the body, further relaxes the heart muscles by reducing the workload on the heart. It also improves the oxygen flow in the body, thereby, preventing any heart-related chest pain.

Common side effects

Headache, Nausea, Abdominal pain, Flushing (sense of warmth in the face, ears, neck and trunk), Dizziness, Palpitations, Edema (swelling), Hypotension (low blood pressure), Chest pain, Fainting, Muscle cramp, Visual disturbance, Shortness of breath, Change in bowel habits, Weakness, Insomnia (difficulty in sleeping), Mood changes, Depression, Tremors, Taste change, Hypoesthesia (decreased sensitivity to stimuli), Paresthesia (tingling or pricking sensation), Arrhythmia (irregular heartbeats), Vomiting, Dryness in mouth, Rash, Muscle pain, Back pain, Frequent urge to urinate, Impotence, Breast enlargement in male, Decreased white blood cell count (lymphocytes), Low blood platelets, Allergic reaction, Increased glucose level in blood, Confusion, Hypertonia (increased muscle tone), Pancreatic inflammation, Gingival hyperplasia, Hepatitis (viral infection of liver), Angioedema (swelling of deeper layers of skin), Stevens-Johnson syndrome
Ramipril(2.5mg)

Uses

Ramipril is used in the treatment of Hypertension (high blood pressure), prevention of heart attack and stroke and Heart failure.

How it works

Ramipril is an angiotensin converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessel so that blood flows more smoothly and the heart can pump blood more efficiently.

Common side effects

Dizziness, Drowsiness, Dry cough, Headache, Fatigue, Nausea, Vomiting, Decreased blood pressure

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Expert advice FOR Ampine RL

  • You have been prescribed Amlodipine to improve your blood pressure and/or to reduce the number and severity of angina attacks.
  • Lowering blood pressure reduces the chance of future heart attack and stroke.
  • Take it at the same time every day to help you remember to take it.
  • A sudden drop in your blood pressure may occur, especially when you first start taking Amlodipine. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • It can cause ankle or foot swelling. To reduce the swelling, raise your legs while you are sitting down. Talk to your doctor if it does not go away.
  • It may cause dizziness. Do not drive or perform any activity that requires mental focus until you know how Amlodipine affects you. 
  • Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding. 

Frequently asked questions FOR Ampine RL

Amlodipine

Q. How long does it take for Amlodipine to work?
Amlodipine starts working on the day it is taken. However, it may take weeks to see the full effect. You should continue taking the medicine even if you feel better or if you do not notice any considerable difference. Consult your doctor if you have any concerns or you feel worse after taking the medicine.
Q. Does Amlodipine cause itching?
Amlodipine may cause itching in some patients, though it is an uncommon side effect. However, if you experience severe itching contact your doctor.
Q. Is Amlodipine bad for the kidneys?
No, there is no evidence that Amlodipine causes deterioration of kidney problems. Amlodipine can be used in normal doses in patients with kidney problems. In fact, its blood pressure-lowering effect, it helps to prevent injury to the kidneys due to hypertension.
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Q. Should I take Amlodipine in the morning or at night?
Amlodipine can be taken anytime of the day. Usually, it is advised to be taken in the morning, but your doctor may advise to take it in the evening as well. You should take it at the same time each day so that you remember to take it and consistent levels of medicine are maintained in the body.
Q. For how long do I need to take Amlodipine?
You should keep on taking Amlodipine for as long as your doctor has recommended you to take it. You may need to take it lifelong. Do not stop taking it, even if you feel well or your blood pressure is well controlled. If you stop taking Amlodipine, your blood pressure may increase again and your condition may worsen.
Q. Is Amlodipine a beta-blocker?
No, Amlodipine is not a beta-blocker. It belongs to a class of medicines known as calcium channel blockers. It lowers blood pressure by relaxing the blood vessels so that blood can easily flow through the blood vessels.
Q. What are the serious side effects of Amlodipine?
Amlodipine may cause some serious side effects such as liver problems (yellowing of skin, nausea, vomiting, and loss of appetite), pancreatitis (severe stomach pain, nausea, and vomiting), and recurrent chest pain which may be indicative of a heart attack. However, these side effects are rarely seen. Remember that your doctor has prescribed this medicine to you because the benefit to you is greater than the risk of any potential side effects. Follow your doctor's advice.
Q. What should I avoid while taking Amlodipine?
Consult your doctor first before starting any new prescription or non-prescription medicines or supplements. Take low sodium and low-fat diet, and adhere to the lifestyle changes as advised by your doctor. Avoid eating grapefruit (chakotra) or drinking grapefruit juice while taking Amlodipine. Stop smoking and taking alcohol as this helps to lower your blood pressure and prevents heart problems.
Q. I have developed ankle edema and swelling over my feet after using a Amlodipine. What should I do?
Amlodipine can cause ankle or foot swelling. To reduce swelling raise your legs while you are sitting down. Talk to your doctor if it does not go away.

Ramipril

Q. I have been diagnosed with heart failure and the doctor has prescribed me Ramipril. Why?
Ramipril belongs to the angiotensin-converting enzyme (ACE) inhibitor group of drugs. It relaxes and widens the blood vessels, making it easier for the blood to pass through the vessels. As a result of this, the heart does not have to work more to push the blood. Since the workload on the heart is reduced, it is beneficial in heart failure. Additionally, it is also used to lower blood pressure and prevent stroke.
Q. When can I expect my blood pressure to be normal after starting Ramipril?
Ramipril takes a few hours to reduce high blood pressure but since there are no symptoms, you will not notice any difference. It takes a few weeks for the blood pressure to get fully controlled. Do not stop taking the medicine. Keep taking it even if you feel better or if your blood pressure is normalized.
Q. Can Ramipril increase potassium levels? If yes, what should be done?
Ramipril may increase potassium levels in the blood, especially if you have uncontrolled diabetes mellitus, kidney problems, and dehydration. Potassium levels may also increase in patients using potassium salts or medicines which increase potassium levels or are aged more than 70 years of age. If you have any of these conditions and are using Ramipril, you need to be careful and get regular blood tests done to monitor potassium levels.
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Q. Ever since I started taking Ramipril, I noticed that I have developed a dry cough which is very irritating and is not relieved by any medicine. Why is it?
Ramipril commonly is responsible for dry cough which can be persistent and is not relieved by any medicine. Talk to your doctor if it bothers you or you have trouble sleeping, as another medicine may be better. Even if you stop taking Ramipril, the cough may take a few days to a month to go away.
Q. I accidentally took a 25 mg Ramipril tablet instead of one 5 mg. Will it have any harmful effects?
Yes, you may feel lightheaded, dizzy, your pulse may become slow and you may even faint. You should take the help of a relative or friend for an emergency or seek immediate medical support.
Q. I have diabetes. Does Ramipril have any effect on blood sugar levels?
Yes, Ramipril may have some effect on antidiabetic medicines and insulin and may lower your blood sugar levels. Therefore, you need to check your blood sugar levels regularly.
Q. I have been using Ramipril for blood pressure for some time, but now I have noticed that I often have a sore throat along with fever. I want to stop Ramipril and see if this goes, can I stop Ramipril?
No, you should not stop Ramipril suddenly as this may cause a sudden increase in your blood pressure which may be harmful to you. In addition to this, Ramipril can very rarely decrease your white blood cell count which is important to fight infections in your body. Consult your doctor and get a blood test done. If your white cell count is decreased, it could be due to Ramipril. Ask your doctor for alternative medicine for blood pressure. You can continue taking Ramipril if your investigations are normal.
Q. Is it safe to take Ramipril for a long time?
Yes, Ramipril is safe and works best if taken for a long time. But, taking Ramipril for a long time can sometimes affect the working of your kidneys. To keep track of this, your doctor will get regular blood tests done and check how well your kidneys are working.
Q. Can Ramipril affect my fertility?
There is no evidence that Ramipril has any effect on fertility in both men and women. However, if you are planning to get pregnant, talk to your doctor first because Ramipril is not recommended in pregnancy.
Q. Will there be any problem if I am taking Ramipril and I have surgery scheduled in a week?
Inform your doctor that you are taking Ramipril. Ramipril can reduce your blood pressure when it is used with a general anesthetic. Your doctor may advise you to stop taking it 24 hours before surgery.

Content on this page was last updated on 29 November, 2023, by Dr. Varun Gupta (MD Pharmacology)