Amitrol DS 25mg/10mg Tablet

Amitriptyline contains Amitriptyline, a tricyclic antidepressant. It has anticholinergic and sedative properties. It prevents the reuptake, and hence the inactivation of neurotransmitters called noradrenaline and serotonin, that are present at the nerve terminals in our brain. Reuptake prevention of these monoamine neurotransmitters potentiate their action in the brain. This appears to be associated with the antidepressant activity and helps in regulating the mood. It also stops the transmission of pain signals from nerves to the brain thereby relieving neuropathic pain (pain from damaged nerves).

Constipation, Dryness in mouth, Orthostatic hypotension (sudden lowering of blood pressure on standing), Weight gain, Aggressive behavior, Nasal congestion (stuffy nose), Sleepiness, Dizziness, Headache, Decreased libido, Nausea, Fatigue, Confusion, Tremors, Speech disorder, Palpitations, Taste change, Paresthesia (tingling or pricking sensation), Abnormality of voluntary movements, Loss of accommodation, Atrioventricular block, Micturition disorders, Erectile dysfunction, Abnormal ECG, Decreased sodium level in blood, Facial swelling, Hypomania, Mania, Anxiety, Insomnia (difficulty in sleeping), Convulsion, Ringing in ear, Rash, Liver impairment, Akathisia (inability to stay still), Suicidal thoughts, Arrhythmia (irregular heartbeats), Hair loss

Chlordiazepoxide is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Confusion, Dizziness, Fatigue, Headache, Jaundice, Sedation, Sleepiness, Unsteadiness, Urinary retention, Abnormality of voluntary movements, Balance disorder (loss of balance), Bone marrow depression, Anaphylactic reaction, Vertigo, Hypotension (low blood pressure), Visual impairment, Rash, Erectile dysfunction, Respiratory depression, Increased appetite, Increased bilirubin in the blood, Increased transaminase level in blood, Increased alkaline phosphatase level in blood, Anterograde amnesia, Drug dependence, Psychiatric disturbances, Paradoxical reactions