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Alzocept-5 M Tablet

Lifecare Neuro Products Ltd
Tablet
Rs.180for 1 strip(s) (10 tablets each)
1
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Composition FOR Alzocept M

Donepezil(5mg),Memantine(10mg)

food interaction for Alzocept M

alcohol interaction for Alzocept M

pregnancy interaction for Alzocept M

lactation interaction for Alzocept M

food
alcohol
pregnancy
lactation
Alzocept-5 M Tablet may be taken with or without food, but it is better to take it at a fixed time.
None
CAUTION
It is unsafe to consume alcohol with Alzocept-5 M Tablet.
UNSAFE
Alzocept-5 M Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
CONSULT YOUR DOCTOR
Information regarding the use of Alzocept-5 M Tablet during breastfeeding is not available. Please consult your doctor.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Alzocept M

Donepezil(5mg)

Uses

Donepezil is used in the treatment of Alzheimer's disease. It should be used in patients with moderate to severe Alzheimer's disease.

How it works

Memory loss in Alzheimer’s disease occurs due to disturbances of signal transmission in the brain. Donepezil is a cholinesterase inhibitor. It works by increasing the levels of a chemical messenger (acetylcholine) involved in transmmission of nerve signals. This improves memory and thinking.

Common side effects

Nausea, Vomiting, Diarrhea, Fatigue, Insomnia (difficulty in sleeping), Headache, Hallucination, Weight loss, Accidental injury, High blood pressure, Ecchymosis (discoloration of the skin resulting from bleeding underneath), Vivid dreams, Joint inflammation, Peptic ulcer, Heart block, Decreased sodium level in blood, Rhabdomyolysis
Memantine(10mg)

Uses

Memantine is used in the treatment of Alzheimer's disease. It should be used in patients with moderate to severe Alzheimer's disease.

How it works

Memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist. Memory loss in Alzheimer’s disease is due to excessive production of glutamate (chemical messenger) in the brain which is mediated by NMDA receptors. Memantine works by preventing the action of NMDA receptors and regulates the production of glutamate.  involved in the transmission of nerve signals. This is how it prevents memory loss in Alzheimer’s disease.

Common side effects

Dizziness, Headache, Confusion, Balance disorder (loss of balance), Weight gain, Vomiting, Drug allergy, High blood pressure, Shortness of breath, Gastrointestinal intolerance, Slow heart rate, Pancreatic inflammation, Blood cell abnormalities, Hallucination, Heart failure, Cholestatic liver disease, Fatigue, Seizure

SUBSTITUTES FOR Alzocept M

38 Substitutes
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38 Substitutes
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Expert advice FOR Alzocept M

  • You have been prescribed Donepezil to slow down the progression of Alzheimer's disease.
  • It does not cure Alzheimer's disease but may help improve brain function and ability to do daily activities.
  • Take it with or without food, preferably at night before going to bed.
  • It may cause diarrhea, nausea, and vomiting. Drink plenty of fluids to keep yourself hydrated while taking Donepezil.
  • Monitor your body weight regularly as both Donepezil and  Alzheimer's disease can cause weight loss.
  • Do not drive or do anything that requires mental focus until you know how Donepezil affects you.
  • Be cautious while taking this medicine if you suffer from peptic ulcer as it may cause vomiting, stomach bleeding, stomach pain, or discomfort.
  • Inform your doctor if you develop muscle tremors, especially if you have Parkinson’s disease.
  • Inform your doctor if you experience seizures or convulsions while taking this medicine.

Frequently asked questions FOR Alzocept M

Donepezil

Q. Why is Donepezil taken at night?
Donepezil is recommended to be taken before going to bed to reduce gastrointestinal side effects or nausea, which is commonly seen in some patients in the first few weeks of treatment.
Q. Do the gastrointestinal side effects due to Donepezil persist for a long time?
Gastrointestinal side effects may appear during the first few weeks of treatment with Donepezil. This can be minimized by taking Donepezil at bedtime and with food. Generally, these side effects are mild and disappear within a few weeks with continued treatment.
Q. How long does it take for Donepezil to start working?
Within the first month of treatment with Donepezil, you may experience improvement in thinking and remembering (cognitive effect). However, it may take about 12 weeks to see the full benefits.
Show More
Q. When should Donepezil be stopped?
Do not stop Donepezil without consulting your doctor. This medicine only helps to control your condition but does not cure it. Therefore, it may take several weeks to show benefits, so do not be discouraged if you do not see an improvement straight away. But, in case your condition starts worsening and you feel that it is no longer helping you, then you should consult a doctor before stopping it.
Q. For how long does Donepezil stay in your system?
Donepezil gets removed from the body very slowly. It takes about two weeks or more for Donepezil to be completely removed from the system.
Q. Does Donepezil cause depression?
No, Donepezil does not cause depression. If you are experiencing symptoms, then it could be due to existing Alzheimer’s disease.
Q. What if I take more than the prescribed dose of Donepezil?
Taking more than the recommended dose of Donepezil may cause vomiting, increased sweating or saliva production, slow heartbeat, dizziness, difficulty in breathing, seizures or fits, weakness, low blood pressure, convulsions, and inability to control your bowel motions or passing of urine (incontinence). You should seek immediate help from a doctor or emergency service of a nearby hospital.
Q. I have been taking indomethacin for arthritis. Can I take Donepezil?
Donepezil does not interfere with the working of indomethacin, but indomethacin individually increases the risk of stomach bleeding when taken for a long time. Therefore, if you experience any symptoms of stomach bleeding, consult your doctor immediately.
Q. Does Donepezil cause hallucinations?
Hallucinations are a common side effect of Donepezil, though not everyone is affected. Other common psychiatric side effects include agitation, aggressive behavior, nightmares, and abnormal dreams.
Q. Who should not take Donepezil?
Donepezil should not be taken by patients who have hypersensitivity to Donepezil hydrochloride, piperidine derivatives, or to any active ingredients used in the medicine. Also, it should not be used during pregnancy unless clearly necessary.
Q. Can it cause insomnia?
Yes, insomnia (sleeplessness) is a common side effect of Donepezil. Dizziness and fainting can also be seen as common side effects. Though these side effects are common, they do not occur in everyone.

Memantine

Q. Does Memantine have abuse potential?
No, Memantine does not have abuse potential. On the contrary, it may prevent excess use of addictive drugs such as morphine or ethanol.
Q. What is dementia?
Dementia is a syndrome in which there is deterioration in memory, thinking, behavior, and the ability to perform everyday activities. Dementia is one of the major causes of disability and dependency among older people worldwide. Alzheimer disease is the most common form of dementia which contributes to around 60 to 70% of cases.
Q. What are the symptoms of overdosage of Memantine?
The symptoms which can be observed due to an overdose of Memantine include tiredness, weakness, drowsiness, confusion, hallucinations, and/or vomiting. Some may also experience diarrhea, vertigo, agitation, aggression, and walking difficulty.
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Q. Can Memantine be combined with donepezil?
Yes, Memantine can be combined with donepezil, as there will be no increased adverse effects. However, this combination will not cure Alzheimer's, but it can only improve thinking ability, short term memory, and other related symptoms.
Q. Does Memantine have any interaction with cardiac medicines?
Yes, Memantine may interfere with the working of hydrochlorothiazide (HCT). It decreases the levels of HCT which will reduce the effectiveness of HCT. Also, procainamide and quinidine may increase levels of Memantine which may cause increased toxicity.
Q. How does Memantine affect a person with dementia?
Memantine belongs to a class of medications called N-methyl-D- aspartate (NMDA) receptor antagonists. It works by decreasing abnormal activity in the brain. Memantine may improve the ability to think and remember. It may also reduce the deterioration of these abilities in people who have Alzheimer's disease. However, with time the effectiveness of this medicine will reduce and it may not be able to cure Alzheimer's disease or prevent the loss of these abilities.
Q. When and how Memantine should be taken?
Memantine should be taken orally once a day. To benefit from your medicine you should take it regularly every day at the same time of the day. The tablets should be swallowed with some water. The tablets can be taken with or without food.
Q. Can I just stop taking Memantine?
No, Memantine should not be stopped even if you feel well. This medicine only helps to control the symptoms of Alzheimer's disease but does not cure it. If you need to stop the medication then doctor should be consulted first.
Q. Can Memantine improve memory?
Memantine belongs to a group of medicines called NMDA receptor antagonists. NMDA receptors are involved in the transmission of nerve signals within the brain such as in learning and memory. This medicine works by protecting NMDA receptors in the brain against high levels of the chemical glutamate, which could be the cause of brain degeneration. By doing so, Memantine may eventually improve your thinking capacity and your ability to remember.
Q. How long does it take for Memantine to start working?
For Memantine to start working and show its full benefits, it may require between 3 and 8 hours. The doctor may require a follow-up clinical assessment to check the progress after 4 weeks and then 6 months after the first assessment.
Q. Does Memantine make you sleepy?
Yes, Memantine may make you sleepy. Memantine has minor to moderate influence on the ability to drive and usage of machines. In such cases, outpatients should be warned to take special care.

Content on this page was last updated on 29 November, 2023, by Dr. Varun Gupta (MD Pharmacology)