Afanat 40 Tablet

Tablet
Rs.5624for 1 strip(s) (28 tablets each)
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Composition FOR Afanat 40mg Tablet

Afatinib dimaleate(40mg)

food interaction for Afanat Tablet

alcohol interaction for Afanat Tablet

pregnancy interaction for Afanat Tablet

lactation interaction for Afanat Tablet

food
alcohol
pregnancy
lactation
Afanat 40 Tablet is to be taken empty stomach.
None
CAUTION
Consuming alcohol with Afanat 40 Tablet does not cause any harmful side effects.
SAFE
Afanat 40 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
CONSULT YOUR DOCTOR
Afanat 40 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
CONSULT YOUR DOCTOR

SALT INFORMATION FOR Afanat 40mg Tablet

Afatinib dimaleate(40mg)

Afanat tablet uses

{med_name} is used in the treatment of non-small cell lung cancer. It is used in patients in whom the cancer has spread to other parts of the body (metastatic), who have abnormal epidermal growth factor receptor (EGFR) genes, and have not been previously treated for metastatic lung cancer.

How afanat tablet works

Afanat 40 Tablet is an anti-cancer medication. It works by binding and inhibiting the enzyme receptors (EGFR, HER2, and HER4) that are responsible for the growth of cancer cells. Hence, resulting in the downregulation of signaling pathways. This is how it to stop or slow the spread of cancer.

Common side effects of afanat tablet

Diarrhea, Rash, Dry skin, Nausea, Vomiting, Loss of appetite, Itching, Stomatitis (Inflammation of the mouth), Nail disorder

SUBSTITUTES FOR Afanat Tablet

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Expert advice FOR Afanat Tablet

  • You have been prescribed Afatinib dimaleate for the treatment of certain type of lung cancer (non-small cell lung cancer). 
  • Take Afatinib dimaleate on an empty stomach at least 1 hour before a meal or 2 hours after a meal. 
  • Diarrhea is common with Afatinib dimaleate and may sometimes be severe. Your doctor may prescribe medicines to treat diarrhea. Stay hydrated and take this medicine exactly as directed. 
  • Afatinib dimaleate can make your skin sensitive to the sun. Limit your time in the sun. Use sunscreen and wear protective clothing if you have to be in sunlight.
  • Afatinib dimaleate can cause redness, rash, and acne. Get treatment for skin reactions as soon as you notice them.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
  • Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
  • Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Frequently asked questions FOR Afanat 40mg Tablet

Afatinib dimaleate

Q. Is Afanat 40 Tablet an immunotherapy or chemotherapy?
Afanat 40 Tablet is neither an immunotherapy nor a conventional chemotherapy. It belongs to kinase inhibitors class of anti-cancer medicines. It works by blocking a group of proteins. These proteins are known to be involved in the growth and spread of cancer cells. By blocking the activity of these proteins, Afanat 40 Tablet stops the cancer cells from growing and multiplying.
Q. How long does it take for Afanat 40 Tablet to work?
The peak levels of Afanat 40 Tablet are reached 2-5 hours after taking it. However, it may take weeks or months to see a noticeable change in the progression of cancer. The symptoms may improve visibly, but the effectiveness of Afanat 40 Tablet can be confirmed only after determining certain parameters.
Q. How should I take Afanat 40 Tablet?
Afanat 40 Tablet is taken by mouth without food, at least 1 hour before or 3 hours after meals. Swallow the complete tablet with water without crushing or breaking it. Take this medicine once daily at about the same time each day. This will make it easier to remember to take this medicine. If you have difficulty in swallowing the tablet, dissolve it in a glass of water. Do not use any other liquid instead of water. Drop the tablet into the water without crushing it and stir occasionally for up to 15 minutes until the tablet is broken up into very small particles. Drink the liquid straight away. Then refill the glass with water and drink it to make sure all medicine is taken.
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Q. Does Afanat 40 Tablet have any effect on fertility?
Afanat 40 Tablet may decrease fertility in both men and women Therefore, if you have any concerns regarding fertility, talk to your doctor who might suggest sperm or egg preservation before starting treatment.
Q. Can Afanat 40 Tablet be given along with chemotherapy?
There are no supporting studies to suggest that Afanat 40 Tablet can be used along with other chemotherapy medicines. Afanat 40 Tablet is used to treat specific type of lung cancer when the prior chemotherapy has been insufficient.
Q. Can Afanat 40 Tablet cure lung cancer?
No, Afanat 40 Tablet cannot cure lung cancer, but it prolongs the survival of the patient. It may also reduce the size of the tumor.
Q. What should I avoid while taking Afanat 40 Tablet?
You should avoid sun exposure as Afanat 40 Tablet can make your skin sensitive to the sun. You may get a severe sunburn or may develop rash or acne or it may get worsened. Therefore, use sunscreen and wear a hat before moving out in the sun. Wear clothes that cover your skin if you have to go out in the sun.
Q. Can I do something if I get diarrhea due to Afanat 40 Tablet?
Diarrhea is a very common side effect of Afanat 40 Tablet. Severe diarrhea can cause excessive loss of body fluids (dehydration) and kidney problems that can sometimes lead to death. Start drinking plenty of fluids at the first signs of diarrhea and contact your doctor immediately. The doctor will start the appropriate antidiarrheal treatment (e.g. loperamide) as soon as possible. The doctor may also reduce your dose or discontinue the therapy if you develop severe diarrhea.

Content on this page was last updated on 28 October, 2024, by Dr. Varun Gupta (MD Pharmacology)