Abglibemide M 5mg/500mg Tablet

Tablet
Rs.42.40for 1 strip(s) (10 tablets each)
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Composition FOR Abglibemide M

Glibenclamide(5mg),Metformin(500mg)

food interaction for Abglibemide M

alcohol interaction for Abglibemide M

pregnancy interaction for Abglibemide M

lactation interaction for Abglibemide M

food
alcohol
pregnancy
lactation
Abglibemide M 5mg/500mg Tablet is to be taken with food.
This medicine may cause stomach upset if taken empty stomach.
None
CAUTION
It is unsafe to consume alcohol with Abglibemide M 5mg/500mg Tablet.
UNSAFE
Abglibemide M 5mg/500mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
SAFE IF PRESCRIBED
Abglibemide M 5mg/500mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
CAUTION

SALT INFORMATION FOR Abglibemide M

Glibenclamide(5mg)

Uses

Glibenclamide is used to lower the blood sugar level in patients with type 2 diabetes mellitus that is not controlled by diet and exercise alone.
. It is used along with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

How it works

Glibenclamide is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.

Common side effects

Hypoglycemia (low blood glucose level), Nausea, Diarrhea, Heartburn, Stomach fullness, Vomiting, Abdominal pain, Allergic reaction, Hepatitis (viral infection of liver), Cholestatic jaundice, Hemolytic anemia, Agranulocytosis (deficiency of granulocytes in the blood), Decreased white blood cell count, Hepatic porphyria, Disulfiram-alcohol reaction
Metformin(500mg)

Uses

 
Metformin is an antidiabetic medicine that helps to control blood sugar in people with type 2 diabetes mellitus.
.

How it works

Metformin is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying the absorption of sugar (glucose) from the intestines, and increasing the body's sensitivity to insulin.

Common side effects

Nausea, Vomiting, Diarrhea, Headache, Flatulence, Indigestion, Hypoglycemia (low blood glucose level), Vitamin B12 deficiency, Abdominal discomfort, Lactic acidosis, Hepatitis (viral infection of liver), Drug eruptions

SUBSTITUTES FOR Abglibemide M

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Expert advice FOR Abglibemide M

  • Take it shortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals.
  • Be careful while driving or operating machinery until you know how Glibenclamide affects you.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Frequently asked questions FOR Abglibemide M

Glibenclamide

Q. Is Glibenclamide the same as Glipizide?
No, Glibenclamide and Glipizide are different medicines. However, they belong to the same class of medicines called sulfonylureas and are used to treat type 2 diabetes mellitus in adults.
Q. Does Glibenclamide play any role in the treatment of polycystic ovarian syndrome (PCOS)?
No, Glibenclamide is not known to have any role in the treatment of polycystic ovarian syndrome (PCOS). Also, there is no clinical evidence available regarding the same.
Q. Why should Glibenclamide be used cautiously in elderly patients?
Glibenclamide should be used with extra caution in elderly patients because they are at high risk of getting low blood sugar (hypoglycemic event).
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Q. Is Glibenclamide useful in the management of prediabetes?
Glibenclamide is not used for the management of prediabetes, a condition with blood glucose levels higher than normal but not high enough to label you as diabetic. There are clinical studies available, but the evidence is not strong enough for its use in prediabetes.
Q. How is Glibenclamide different from Teneligliptin?
Both Glibenclamide and Teneligliptin are antidiabetic medicines and control blood sugar levels effectively. However, they work in different ways and may show different kinds of side effects. Glibenclamide commonly causes hypoglycemia and weight gain while Teneligliptin causes headache and nasopharyngitis. Teneligliptin causes hypoglycemia when used along with insulins or sulfonylureas and does not cause weight gain.
Q. Can I skip Glibenclamide for a few days?
No, Glibenclamide should not be skipped as it can make your diabetes worse. If you miss the dose by mistake, take it as soon as you remember.
Q. Can I take Glibenclamide if I have a sulfa allergy?
Use of Glibenclamide should be avoided if you are allergic (hypersensitive) to sulfonylureas or sulfonamides or any of the other ingredients of this medicine.
Q. Does Glibenclamide cause weight gain?
Yes, Glibenclamide can cause weight gain. It is advisable to closely monitor your diet and exercise regularly while taking this medicine. Avoid skipping your meals as it can cause very low blood sugar levels and you may end up snacking or taking a lot of sugars.
Q. Is there any benefit of taking Glibenclamide with insulin?
Glibenclamide, when used with insulin, can help to control high blood sugar levels. Taking them together can help to lower the dose of insulin but there could also be an increased risk of hypoglycemia (low blood sugar levels). The dose of these medicines may need to be adjusted along with regular blood sugar level monitoring. Please consult your doctor if you have any doubts and follow your doctor's instructions carefully to get maximum benefit of Glibenclamide.
Q. Is it safe to take Glibenclamide with Liraglutide?
Yes, Glibenclamide and Liraglutide can be taken together, as they can help in better control of blood sugar levels. However, the risk of low blood sugar levels (hypoglycemia) can increase. Consult your doctor as a dose adjustment of the two may be needed.
Q. Is Glibenclamide a Thiazolidinedione?
No, Glibenclamide is not a Thiazolidinedione, it is a sulfonylurea. However, both are antidiabetic medicines but belong to a different group of medicines.
Q. Is Glibenclamide useful in the management of gestational diabetes?
Glibenclamide is not advised to be used for the management of gestational diabetes. The use of insulin is advised during pregnancy to control the blood glucose levels. However, do not start taking Glibenclamide until prescribed by the doctor.
Q. Does Glibenclamide cause hair loss?
No, hair loss is not seen with the use of Glibenclamide. However, diabetes can lead to hair loss. Talk to your doctor if you have excessive hair loss as it could be due to some other underlying condition or it could be a sign of your diabetes getting worsened.
Q. Is it safe to take Glibenclamide with pioglitazone?
Yes, it is safe to take Glibenclamide with Pioglitazone in patients with diabetes mellitus. Together these two medicines can control your blood sugar levels, lower plasma lipid levels and improve blood pressure. However, the risk of very low blood sugar levels can increase and the dose of these medicines may need to be adjusted.

Metformin

Q. What does Metformin do exactly?
People with type 2 diabetes are not able to make enough insulin or respond normally to the insulin made by their bodies. When this happens, the concentration of sugar/glucose increases in the blood. Metformin acts in several ways to reduce the increased levels of sugar in blood. Metformin decreases glucose production from the liver and decreases absorption of glucose from the intestine after taking food while improving the sensitivity of the body organs and muscles towards insulin. This helps improve the uptake of glucose from the blood. It also helps your body to respond better to the insulin it makes naturally.
Q. Does Metformin cause weight loss?
Yes, Metformin has been shown to cause weight loss in people who are overweight or obese. It may also cause a modest loss in weight in those overweight and obese individuals who are at risk for diabetes. In addition, patients who are sensitive or resistant to insulin may also show weight loss. But, do not start taking this medicine for weight loss on your own. Consult your doctor for the same.
Q. What are the benefits of taking Metformin?
Metformin is one of the first medicines that is given to patients with high blood sugar levels. It helps control blood sugar levels. It promotes the body’s response to the insulin made by the pancreas, decreases the amount of sugar made by the liver and decreases the amount of sugar absorbed by the intestines. Unlike other oral antidiabetic medicines, Metformin when taken alone, rarely causes low blood sugar as it prevents the pancreas from secreting more insulin. In addition to being a great medicine to lower blood sugar levels, it also helps in controlling weight gain.
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Q. Can Metformin make you sleepy?
Metformin usually does not cause sleepiness and is well tolerated. However, the use of Metformin may rarely cause sleep disorders and insomnia. Sleepiness may be due to a very serious side effect called lactic acidosis, which particularly occurs if your kidneys are not working properly. Contact your doctor if you feel sleepy or tired while taking Metformin.
Q. How to take Metformin?
Take Metformin with or after a meal. Do not crush or chew the tablets and swallow it with a glass of water. If your doctor has prescribed one tablet a day, prefer taking it in the morning with breakfast. If you have been prescribed two tablets a day, then take one in the morning and other in the evening with dinner. In case of three doses a day, apart from morning and evening, you can take it with lunch. Taking Metformin with meals will reduce its digestive problems like indigestion, nausea, vomiting, diarrhea, stomach ache and loss of appetite.

Content on this page was last updated on 29 November, 2023, by Dr. Varun Gupta (MD Pharmacology)